Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPM6A
  • Mouse genes Gpm6a
  • Rat genes Gpm6a
  • Zfish genes gpm6aa,gpm6ab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gpm6a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005262	calcium channel activity	Gpm6a	IDA		Rat	PMID:12359212|RGD:708586
Molecular Function	GO:0005515	protein binding	GPM6A	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	GPM6A	IPI	UniProtKB:Q8IUH5	Human	PMID:24705354
Molecular Function	GO:0005515	protein binding	GPM6A	IPI	UniProtKB:Q5T9L3-1	Human	PMID:31286866
Molecular Function	GO:0005515	protein binding	GPM6A	IPI	UniProtKB:O14901	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GPM6A	IPI	UniProtKB:P37173	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GPM6A	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GPM6A	IPI	UniProtKB:Q9UMF0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Gpm6a	IPI	UniProtKB:P33535	Rat	PMID:17548356|RGD:8554757
Cellular Component	GO:0044295	axonal growth cone	Gpm6a	IDA		Mouse	MGI:MGI:5426131|PMID:21714103
Cellular Component	GO:0070062	extracellular exosome	GPM6A	HDA		Human	PMID:19056867
Cellular Component	GO:1903561	extracellular vesicle	GPM6A	HDA		Human	PMID:24769233
Cellular Component	GO:0030175	filopodium	Gpm6a	IDA		Rat	PMID:16286650|RGD:8554337
Cellular Component	GO:0098978	glutamatergic synapse	Gpm6a	IDA		Rat	PMID:10447243|RGD:155230692
Cellular Component	GO:0098978	glutamatergic synapse	Gpm6a	EXP		Rat	PMID:23622064|RGD:13702180
Cellular Component	GO:0098978	glutamatergic synapse	Gpm6a	IDA		Rat	PMID:23622064|RGD:13702180
Cellular Component	GO:0098978	glutamatergic synapse	Gpm6a	IDA		Rat	PMID:27793698|RGD:13702167
Cellular Component	GO:0098978	glutamatergic synapse	Gpm6a	IMP		Rat	PMID:27793698|RGD:13702167
Cellular Component	GO:0043005	neuron projection	Gpm6a	IDA		Rat	PMID:21426347|RGD:8553615
Cellular Component	GO:0043025	neuronal cell body	Gpm6a	IDA		Rat	PMID:21426347|RGD:8553615
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	Gpm6a	IDA		Rat	PMID:10447243|RGD:155230692
Cellular Component	GO:0005886	plasma membrane	Gpm6a	IDA		Rat	PMID:16286650|RGD:8554337
Cellular Component	GO:0005886	plasma membrane	Gpm6a	IDA		Rat	PMID:21426347|RGD:8553615
Cellular Component	GO:0098793	presynapse	Gpm6a	IDA		Rat	PMID:10447243|RGD:155230692
Cellular Component	GO:0048787	presynaptic active zone membrane	Gpm6a	EXP		Rat	PMID:23622064|RGD:13702180
Cellular Component	GO:0048787	presynaptic active zone membrane	Gpm6a	IDA		Rat	PMID:23622064|RGD:13702180
Biological Process	GO:0003407	neural retina development	Gpm6a	IDA		Mouse	MGI:MGI:3811956|PMID:18776950
Biological Process	GO:0001764	neuron migration	GPM6A	IDA		Human	PMID:19298174
Biological Process	GO:0031175	neuron projection development	gpm6ab	IDA		Zfish	PMID:22028883
Biological Process	GO:0048812	neuron projection morphogenesis	Gpm6a	IDA		Mouse	MGI:MGI:3811956|PMID:18776950
Biological Process	GO:0051491	positive regulation of filopodium assembly	Gpm6a	IDA		Rat	PMID:21426347|RGD:8553615
Biological Process	GO:0051489	regulation of filopodium assembly	gpm6ab	IDA		Zfish	PMID:22028883
Biological Process	GO:0050807	regulation of synapse organization	Gpm6a	IDA		Rat	PMID:27793698|RGD:13702167
Biological Process	GO:0050807	regulation of synapse organization	Gpm6a	IMP		Rat	PMID:27793698|RGD:13702167
Biological Process	GO:0009617	response to bacterium	Gpm6a	IEP		Mouse	PMID:23012479
Biological Process	GO:0048863	stem cell differentiation	GPM6A	IDA		Human	PMID:19298174
Biological Process	GO:0007416	synapse assembly	Gpm6a	IDA		Rat	PMID:19737934|RGD:8554345

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern