Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPR183
  • Mouse genes Gpr183
  • Rat genes Gpr183
  • Zfish genes gpr183a,gpr183b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gpr183

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004930	G protein-coupled receptor activity	GPR183	IDA		Human	PMID:18628402
Molecular Function	GO:0004930	G protein-coupled receptor activity	GPR183	IDA		Human	PMID:22875855
Molecular Function	GO:0004930	G protein-coupled receptor activity	GPR183	IDA		Human	PMID:22930711
Molecular Function	GO:0008142	oxysterol binding	GPR183	IDA		Human	PMID:21796212
Molecular Function	GO:0008142	oxysterol binding	GPR183	IDA		Human	PMID:22875855
Molecular Function	GO:0008142	oxysterol binding	GPR183	IDA		Human	PMID:22930711
Molecular Function	GO:0008142	oxysterol binding	GPR183	IMP		Human	PMID:24678947
Molecular Function	GO:0008142	oxysterol binding	Gpr183	IDA		Mouse	MGI:MGI:5140626|PMID:21796211
Molecular Function	GO:0005515	protein binding	gpr183a	IPI	ZFIN:ZDB-GENE-060824-1	Zfish	PMID:26358189
Cellular Component	GO:0005886	plasma membrane	GPR183	IDA		Human	PMID:18628402
Cellular Component	GO:0005886	plasma membrane	GPR183	IDA		Human	PMID:21673108
Cellular Component	GO:0005886	plasma membrane	GPR183	IDA		Human	PMID:22930711
Biological Process	GO:0002250	adaptive immune response	Gpr183	IMP		Mouse	MGI:MGI:5488535|PMID:23502855
Biological Process	GO:0002250	adaptive immune response	Gpr183	IMP		Mouse	MGI:MGI:5498633|PMID:23682316
Biological Process	GO:0060326	cell chemotaxis	Gpr183	IMP		Mouse	MGI:MGI:5750254|PMID:26438360
Biological Process	GO:0060216	definitive hemopoiesis	gpr183a	IMP	ZFIN:ZDB-GENO-170428-3	Zfish	PMID:26358189
Biological Process	GO:0002407	dendritic cell chemotaxis	Gpr183	IMP		Mouse	MGI:MGI:5488535|PMID:23502855
Biological Process	GO:0002407	dendritic cell chemotaxis	Gpr183	IMP		Mouse	MGI:MGI:5498633|PMID:23682316
Biological Process	GO:0036145	dendritic cell homeostasis	Gpr183	IMP		Mouse	MGI:MGI:5498633|PMID:23682316
Biological Process	GO:0036145	dendritic cell homeostasis	Gpr183	IMP		Mouse	MGI:MGI:5488535|PMID:23502855
Biological Process	GO:0098508	endothelial to hematopoietic transition	gpr183a	IGI	ZFIN:ZDB-GENE-051005-2	Zfish	PMID:26358189
Biological Process	GO:0098508	endothelial to hematopoietic transition	gpr183a	IMP	ZFIN:ZDB-GENO-170428-3	Zfish	PMID:26358189
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	GPR183	IDA		Human	PMID:18628402
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	GPR183	IDA		Human	PMID:21673108
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	GPR183	IDA		Human	PMID:22875855
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	GPR183	IDA		Human	PMID:22930711
Biological Process	GO:0006959	humoral immune response	Gpr183	IMP		Mouse	MGI:MGI:4352759|PMID:19597478
Biological Process	GO:0006959	humoral immune response	Gpr183	IMP		Mouse	MGI:MGI:5498633|PMID:23682316
Biological Process	GO:0006959	humoral immune response	Gpr183	IMP		Mouse	MGI:MGI:5488535|PMID:23502855
Biological Process	GO:0030595	leukocyte chemotaxis	GPR183	IMP		Human	PMID:24678947
Biological Process	GO:0030595	leukocyte chemotaxis	Gpr183	IDA		Mouse	PMID:25348153
Biological Process	GO:0002313	mature B cell differentiation involved in immune response	Gpr183	IMP		Mouse	MGI:MGI:4352759|PMID:19597478
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	gpr183a	IMP	ZFIN:ZDB-GENO-170428-3	Zfish	PMID:26358189
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	gpr183a	IGI	ZFIN:ZDB-GENE-060824-1	Zfish	PMID:26358189
Biological Process	GO:0030316	osteoclast differentiation	Gpr183	IMP		Mouse	MGI:MGI:5750254|PMID:26438360
Biological Process	GO:0030890	positive regulation of B cell proliferation	GPR183	IDA		Human	PMID:21673108
Biological Process	GO:0030890	positive regulation of B cell proliferation	Gpr183	IDA		Mouse	MGI:MGI:5430842|PMID:21673108
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	GPR183	IDA		Human	PMID:21673108
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	GPR183	IDA		Human	PMID:25297897
Biological Process	GO:2000458	regulation of astrocyte chemotaxis	GPR183	IDA		Human	PMID:25297897
Biological Process	GO:0010818	T cell chemotaxis	Gpr183	IMP		Mouse	MGI:MGI:5787848|PMID:27147029
Biological Process	GO:0061470	T follicular helper cell differentiation	Gpr183	IMP		Mouse	MGI:MGI:5787848|PMID:27147029

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern