Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPR22
  • Mouse genes Gpr22
  • Rat genes Gpr22
  • Zfish genes gpr22a,gpr22b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gpr22

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004930	G protein-coupled receptor activity	GPR22	IMP		Human	PMID:18539757
Cellular Component	GO:0005886	plasma membrane	Gpr22	IDA		Rat	PMID:18539757|RGD:13702384
Biological Process	GO:0071907	determination of digestive tract left/right asymmetry	gpr22a	IMP	ZFIN:ZDB-MRPHLNO-150129-2	Zfish	PMID:25335082
Biological Process	GO:0061371	determination of heart left/right asymmetry	gpr22a	IMP	ZFIN:ZDB-MRPHLNO-150129-2	Zfish	PMID:25335082
Biological Process	GO:0003140	determination of left/right asymmetry in lateral mesoderm	gpr22a	IMP	ZFIN:ZDB-MRPHLNO-150129-2	Zfish	PMID:25335082
Biological Process	GO:0007368	determination of left/right symmetry	gpr22a	IMP	ZFIN:ZDB-MRPHLNO-150129-2	Zfish	PMID:25335082
Biological Process	GO:0071910	determination of liver left/right asymmetry	gpr22a	IMP	ZFIN:ZDB-MRPHLNO-150129-2	Zfish	PMID:25335082
Biological Process	GO:0001947	heart looping	gpr22a	IMP	ZFIN:ZDB-MRPHLNO-150129-2	Zfish	PMID:25335082
Biological Process	GO:0070121	Kupffer's vesicle development	gpr22a	IMP	ZFIN:ZDB-MRPHLNO-150129-2	Zfish	PMID:25335082

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern