Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPR35
  • Mouse genes Gpr35
  • Rat genes Gpr35
  • Zfish genes gpr35.1,gpr35.2,gpr35b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gpr35

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016494	C-X-C chemokine receptor activity	GPR35	IMP		Human	PMID:25411203
Molecular Function	GO:0004930	G protein-coupled receptor activity	GPR35	IDA		Human	PMID:16754668
Molecular Function	GO:0004930	G protein-coupled receptor activity	GPR35	IDA		Human	PMID:17940199
Molecular Function	GO:0004930	G protein-coupled receptor activity	Gpr35	IDA		Rat	PMID:17996730|RGD:150521655
Cellular Component	GO:0005886	plasma membrane	GPR35	IDA		Human	PMID:16754668
Cellular Component	GO:0005886	plasma membrane	Gpr35	IDA		Mouse	MGI:MGI:3694325|PMID:16754668
Cellular Component	GO:0005886	plasma membrane	Gpr35	IDA		Mouse	MGI:MGI:5805362|PMID:24095869
Cellular Component	GO:0005886	plasma membrane	Gpr35	IDA		Rat	PMID:16754668|RGD:150521624
Cellular Component	GO:0005886	plasma membrane	Gpr35	IDA		Rat	PMID:25542997|RGD:11541110
Biological Process	GO:0070098	chemokine-mediated signaling pathway	GPR35	IDA		Human	PMID:25411203
Biological Process	GO:0070098	chemokine-mediated signaling pathway	GPR35	IMP		Human	PMID:25411203
Biological Process	GO:0007010	cytoskeleton organization	Gpr35	IDA		Mouse	MGI:MGI:5805362|PMID:24095869
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	GPR35	IDA		Human	PMID:16754668
Biological Process	GO:1904456	negative regulation of neuronal action potential	Gpr35	IMP		Rat	PMID:17940199|RGD:11541107
Biological Process	GO:1901386	negative regulation of voltage-gated calcium channel activity	GPR35	IMP		Human	PMID:17940199
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	GPR35	IMP		Human	PMID:25411203

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern