Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPR37
  • Mouse genes Gpr37
  • Rat genes Gpr37
  • Zfish genes gpr37a,gpr37b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gpr37

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008528	G protein-coupled peptide receptor activity	GPR37	IDA		Human	PMID:23690594
Molecular Function	GO:0031072	heat shock protein binding	GPR37	IPI	UniProtKB:P31689	Human	PMID:12150907
Molecular Function	GO:0030544	Hsp70 protein binding	GPR37	IPI	UniProtKB:P11142	Human	PMID:12150907
Molecular Function	GO:0042923	neuropeptide binding	GPR37	IPI	UniProtKB:P69251	Human	PMID:16443751
Molecular Function	GO:0008188	neuropeptide receptor activity	GPR37	IDA		Human	PMID:16443751
Molecular Function	GO:0030165	PDZ domain binding	Gpr37	IPI	UniProtKB:Q8VBX6	Mouse	PMID:25977097
Molecular Function	GO:0042277	peptide binding	GPR37	IPI	UniProtKB:Q61207	Human	PMID:23690594
Molecular Function	GO:0036505	prosaposin receptor activity	GPR37	IDA		Human	PMID:23690594
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:Q96M98	Human	PMID:14532270
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:Q01959	Human	PMID:17519329
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:O95070	Human	PMID:28298427
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:P08195	Human	PMID:28298427
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:P29274	Human	PMID:28298427
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:Q13639	Human	PMID:28298427
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:Q5BJH7	Human	PMID:28298427
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:Q9H313	Human	PMID:28298427
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:Q9NX61	Human	PMID:28298427
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:Q9UBS5	Human	PMID:28298427
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:A0A024R4B0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:D3DTF8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:O15540	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:P25490	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:P34741	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:Q02930-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:Q14671	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:Q14995	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:Q5HYJ3-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:Q5TA79	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:Q71RG4-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:Q7L8T7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:Q7Z7K5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:Q8IXL7-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:Q969E2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GPR37	IPI	UniProtKB:Q9C0A1	Human	PMID:32814053
Molecular Function	GO:0031625	ubiquitin protein ligase binding	GPR37	IPI	UniProtKB:O60260	Human	PMID:11439185
Molecular Function	GO:0031625	ubiquitin protein ligase binding	GPR37	IPI	UniProtKB:O60260	Human	PMID:12150907
Molecular Function	GO:0031625	ubiquitin protein ligase binding	GPR37	IPI	UniProtKB:Q9UNE7	Human	PMID:12150907
Molecular Function	GO:0031625	ubiquitin protein ligase binding	GPR37	IPI	UniProtKB:Q86TM6	Human	PMID:17059562
Cellular Component	GO:0009986	cell surface	GPR37	IDA		Human	PMID:16443751
Cellular Component	GO:0009986	cell surface	Gpr37	IMP		Mouse	PMID:25977097
Cellular Component	GO:0005737	cytoplasm	GPR37	IDA		Human	PMID:16443751
Cellular Component	GO:0005783	endoplasmic reticulum	GPR37	IDA		Human	PMID:17059562
Cellular Component	GO:0005886	plasma membrane	GPR37	IDA		Human	PMID:11439185
Cellular Component	GO:0005886	plasma membrane	GPR37	IDA		Human	PMID:12150907
Cellular Component	GO:0043235	receptor complex	GPR37	IDA		Human	PMID:23382219
Cellular Component	GO:0045202	synapse	Gpr37	IDA		Mouse	PMID:25977097
Cellular Component	GO:0000151	ubiquitin ligase complex	GPR37	IDA		Human	PMID:12150907
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	GPR37	IDA		Human	PMID:23690594
Biological Process	GO:0016358	dendrite development	Gpr37	IMP		Mouse	PMID:25977097
Biological Process	GO:0042416	dopamine biosynthetic process	Gpr37	IMP	MGI:MGI:3027995	Mouse	PMID:15218106
Biological Process	GO:0031987	locomotion involved in locomotory behavior	Gpr37	IMP	MGI:MGI:3027995	Mouse	PMID:15218106
Biological Process	GO:1903206	negative regulation of hydrogen peroxide-induced cell death	Gpr37	IMP		Mouse	MGI:MGI:5586790|PMID:23690594
Biological Process	GO:0007218	neuropeptide signaling pathway	GPR37	IDA		Human	PMID:16443751
Biological Process	GO:0045964	positive regulation of dopamine metabolic process	Gpr37	IMP	MGI:MGI:3027995	Mouse	PMID:15218106
Biological Process	GO:0043410	positive regulation of MAPK cascade	GPR37	IDA		Human	PMID:23690594
Biological Process	GO:0043410	positive regulation of MAPK cascade	Gpr37	IMP		Mouse	MGI:MGI:5586790|PMID:23690594

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern