Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPRC5A
  • Mouse genes Gprc5a
  • Rat genes Gprc5a
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gprc5a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	GPRC5A	HDA		Human	PMID:25468996
Molecular Function	GO:0005515	protein binding	GPRC5A	IPI	UniProtKB:P00533	Human	PMID:25311788
Molecular Function	GO:0005515	protein binding	Gprc5a	IPI	UniProtKB:Q01279	Mouse	MGI:MGI:5635952|PMID:25744720
Cellular Component	GO:0070062	extracellular exosome	GPRC5A	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	GPRC5A	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	GPRC5A	HDA		Human	PMID:23533145
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	GPRC5A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	GPRC5A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	GPRC5A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	GPRC5A	IDA		Human	PMID:18000218
Cellular Component	GO:0005886	plasma membrane	Gprc5a	IDA		Mouse	MGI:MGI:3765112|PMID:18000218
Cellular Component	GO:0031982	vesicle	GPRC5A	IDA		Human	PMID:25468996
Biological Process	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	Gprc5a	IMP		Mouse	MGI:MGI:5635952|PMID:25744720

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern