Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPS2
  • Mouse genes Gps2
  • Rat genes Gps2
  • Zfish genes gps2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gps2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030332	cyclin binding	GPS2	IPI	UniProtKB:P78396	Human	PMID:15159402
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:O60907	Human	PMID:11931768
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:O75376	Human	PMID:11931768
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:P18848	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:P57077	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:O15379	Human	PMID:16980585
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:O15379	Human	PMID:17895379
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q13547	Human	PMID:17895379
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q9WMX2:PRO_0000037551	Human	PMID:18985028
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q13133	Human	PMID:19481530
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:A0A024RBS3	Human	PMID:21240272
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:O60907-2	Human	PMID:21240272
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:O15379	Human	PMID:21258344
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:P12504	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q9UPS8	Human	PMID:22666460
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:O15379	Human	PMID:23752268
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:P18848	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q15311	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q15323	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q86VW0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q93062	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q9UBB9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q06986	Human	PMID:26070566
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q6NZB1	Human	PMID:26070566
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q9QXE7	Human	PMID:26070566
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:O60907-2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q15311	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:P18848	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q86VW0	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q15311	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:A1KXE4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:A5D8V6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:O43482	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:O76011	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:O76013-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:O95429	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:P18848	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:P31943	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q05BL1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q15038	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q15311	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q15654	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q16633	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q3LI64	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q3LI66	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q52LG2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q53HV7-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q5BKX5-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q5TA45	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q5TD97	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q7Z3Y8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q86VW0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q8IUC1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q8WUN7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q9BYR6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q9BYR8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q9UBB9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q9UHB4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q9ULX6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPS2	IPI	UniProtKB:Q9Y2D1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Gps2	IPI	UniProtKB:P61089	Mouse	MGI:MGI:6148454|PMID:22424771
Molecular Function	GO:0005515	protein binding	Gps2	IPI	PR:Q7TNK1	Mouse	PMID:18218630
Molecular Function	GO:0003713	transcription coactivator activity	GPS2	IDA		Human	PMID:19481530
Molecular Function	GO:0003713	transcription coactivator activity	Gps2	IDA		Mouse	MGI:MGI:6148396|PMID:29499132
Molecular Function	GO:0003713	transcription coactivator activity	Gps2	IDA		Mouse	MGI:MGI:6148392|PMID:24953653
Molecular Function	GO:0003714	transcription corepressor activity	GPS2	IDA		Human	PMID:11931768
Molecular Function	GO:0003714	transcription corepressor activity	GPS2	IDA		Human	PMID:19858209
Molecular Function	GO:0003714	transcription corepressor activity	Gps2	IDA		Mouse	MGI:MGI:5620549|PMID:25519902
Cellular Component	GO:0005737	cytoplasm	Gps2	IDA		Mouse	MGI:MGI:6148454|PMID:22424771
Cellular Component	GO:0005829	cytosol	GPS2	IDA		Human	PMID:29499132
Cellular Component	GO:0005739	mitochondrion	GPS2	IDA		Human	PMID:29499132
Cellular Component	GO:0005739	mitochondrion	Gps2	IDA		Mouse	MGI:MGI:6148396|PMID:29499132
Cellular Component	GO:0005634	nucleus	GPS2	IDA		Human	PMID:19858209
Cellular Component	GO:0005634	nucleus	GPS2	IDA		Human	PMID:29499132
Cellular Component	GO:0005634	nucleus	Gps2	IDA		Mouse	MGI:MGI:6148396|PMID:29499132
Cellular Component	GO:0005634	nucleus	Gps2	IDA		Mouse	MGI:MGI:5908330|PMID:22666460
Cellular Component	GO:0005634	nucleus	Gps2	IDA		Mouse	MGI:MGI:6148454|PMID:22424771
Cellular Component	GO:0005634	nucleus	Gps2	IDA		Mouse	MGI:MGI:5688415|PMID:26070566
Cellular Component	GO:0005634	nucleus	Gps2	IDA		Mouse	PMID:18218630
Cellular Component	GO:0017053	transcription repressor complex	GPS2	IDA		Human	PMID:12628926
Cellular Component	GO:0017053	transcription repressor complex	GPS2	IDA		Human	PMID:19858209
Cellular Component	GO:0017053	transcription repressor complex	Gps2	IDA		Mouse	MGI:MGI:5620549|PMID:25519902
Biological Process	GO:0030183	B cell differentiation	Gps2	IMP		Mouse	MGI:MGI:5896692|PMID:28039360
Biological Process	GO:0050859	negative regulation of B cell receptor signaling pathway	Gps2	IMP		Mouse	MGI:MGI:5896692|PMID:28039360
Biological Process	GO:0045599	negative regulation of fat cell differentiation	Gps2	IMP		Mouse	MGI:MGI:5908330|PMID:22666460
Biological Process	GO:0050728	negative regulation of inflammatory response	Gps2	IDA		Mouse	MGI:MGI:6148454|PMID:22424771
Biological Process	GO:0046329	negative regulation of JNK cascade	GPS2	IDA		Human	PMID:11931768
Biological Process	GO:0046329	negative regulation of JNK cascade	Gps2	IMP		Mouse	MGI:MGI:6148454|PMID:22424771
Biological Process	GO:1900045	negative regulation of protein K63-linked ubiquitination	Gps2	IDA		Mouse	MGI:MGI:6148396|PMID:29499132
Biological Process	GO:1900045	negative regulation of protein K63-linked ubiquitination	Gps2	IMP		Mouse	MGI:MGI:5896692|PMID:28039360
Biological Process	GO:1900045	negative regulation of protein K63-linked ubiquitination	Gps2	IDA		Mouse	MGI:MGI:6148454|PMID:22424771
Biological Process	GO:1900045	negative regulation of protein K63-linked ubiquitination	Gps2	IDA		Mouse	MGI:MGI:6148392|PMID:24953653
Biological Process	GO:0034122	negative regulation of toll-like receptor signaling pathway	Gps2	IMP		Mouse	MGI:MGI:5896692|PMID:28039360
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	GPS2	IDA		Human	PMID:11931768
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	GPS2	IDA		Human	PMID:19858209
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Gps2	IDA		Mouse	MGI:MGI:5620549|PMID:25519902
Biological Process	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	Gps2	IMP		Mouse	MGI:MGI:6148454|PMID:22424771
Biological Process	GO:0010875	positive regulation of cholesterol efflux	GPS2	IDA		Human	PMID:19481530
Biological Process	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway	Gps2	IDA		Mouse	MGI:MGI:6148392|PMID:24953653
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	GPS2	IDA		Human	PMID:19481530
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Gps2	IDA		Mouse	MGI:MGI:6148392|PMID:24953653
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Gps2	IDA		Mouse	MGI:MGI:6148396|PMID:29499132
Biological Process	GO:0045598	regulation of fat cell differentiation	Gps2	IDA		Mouse	MGI:MGI:6148392|PMID:24953653
Biological Process	GO:0019216	regulation of lipid metabolic process	Gps2	IDA		Mouse	MGI:MGI:6148392|PMID:24953653
Biological Process	GO:0098780	response to mitochondrial depolarisation	Gps2	IDA		Mouse	MGI:MGI:6148396|PMID:29499132

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern