Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPX3
  • Mouse genes Gpx3
  • Rat genes Gpx3
  • Zfish genes gpx3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gpx3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004602	glutathione peroxidase activity	GPX3	IDA		Human	PMID:1897960
Molecular Function	GO:0004602	glutathione peroxidase activity	GPX3	IDA		Human	PMID:3693360
Molecular Function	GO:0004602	glutathione peroxidase activity	Gpx3	IDA		Mouse	PMID:10617683
Molecular Function	GO:0004602	glutathione peroxidase activity	Gpx3	IDA		Rat	PMID:16140890|RGD:1624364
Molecular Function	GO:0042802	identical protein binding	GPX3	IPI	UniProtKB:P22352	Human	PMID:3693360
Molecular Function	GO:0005515	protein binding	GPX3	IPI	UniProtKB:Q9UMX0-2	Human	PMID:25416956
Molecular Function	GO:0008430	selenium binding	GPX3	IDA		Human	PMID:2491950
Molecular Function	GO:0008430	selenium binding	GPX3	IDA		Human	PMID:3693360
Molecular Function	GO:0008430	selenium binding	Gpx3	IDA		Rat	PMID:10746307|RGD:2312788
Cellular Component	GO:0070062	extracellular exosome	GPX3	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	GPX3	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	GPX3	IDA		Human	PMID:1897960
Cellular Component	GO:0005615	extracellular space	Gpx3	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Gpx3	IDA		Rat	PMID:14673789|RGD:2312628
Biological Process	GO:0098869	cellular oxidant detoxification	Gpx3	IDA		Mouse	MGI:MGI:1352605|PMID:10617683
Biological Process	GO:0006749	glutathione metabolic process	Gpx3	IDA		Rat	PMID:16140890|RGD:1624364
Biological Process	GO:0042744	hydrogen peroxide catabolic process	Gpx3	IDA		Mouse	PMID:10617683
Biological Process	GO:0042744	hydrogen peroxide catabolic process	Gpx3	IDA		Rat	PMID:16140890|RGD:1624364
Biological Process	GO:0051412	response to corticosterone	Gpx3	IEP		Rat	PMID:15755911|RGD:2312627
Biological Process	GO:0002238	response to molecule of fungal origin	Gpx3	IEP		Rat	PMID:18279679|RGD:2312625
Biological Process	GO:0014070	response to organic cyclic compound	Gpx3	IEP		Rat	PMID:14673789|RGD:2312628
Biological Process	GO:0010033	response to organic substance	Gpx3	IEP		Rat	PMID:18306454|RGD:2312624
Biological Process	GO:0010269	response to selenium ion	Gpx3	IEP		Rat	PMID:19398061|RGD:2312622
Biological Process	GO:0009410	response to xenobiotic stimulus	Gpx3	IEP		Rat	PMID:18598687|RGD:2312623

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern