Source |
Alliance of Genome Resources |
Category | ID | Classification term | Gene | Evidence | Inferred from | Organism | Reference |
---|---|---|---|---|---|---|---|
Molecular Function | GO:0036122 | BMP binding | GREM1 | IDA | Human | PMID:27036124 | |
Molecular Function | GO:0005515 | protein binding | GREM1 | IPI | UniProtKB:Q04917 | Human | PMID:16545136 |
Molecular Function | GO:0005515 | protein binding | GREM1 | IPI | UniProtKB:P35968 | Human | PMID:20660291 |
Molecular Function | GO:0005515 | protein binding | GREM1 | IPI | UniProtKB:O60565 | Human | PMID:27036124 |
Molecular Function | GO:0005515 | protein binding | GREM1 | IPI | UniProtKB:P59991 | Human | PMID:32296183 |
Molecular Function | GO:0005515 | protein binding | GREM1 | IPI | UniProtKB:Q99750 | Human | PMID:32296183 |
Molecular Function | GO:0005515 | protein binding | Grem1 | IPI | RGD:730832 | Rat | PMID:10722723|RGD:2303398 |
Molecular Function | GO:0005515 | protein binding | Grem1 | IPI | RGD:733848|RGD:733021 | Rat | PMID:15528323|RGD:2303400 |
Molecular Function | GO:0005515 | protein binding | Grem1 | IPI | UniProtKB:O88279 | Rat | PMID:15528323|RGD:2303400 |
Molecular Function | GO:0005515 | protein binding | Grem1 | IPI | UniProtKB:Q9WVC1 | Rat | PMID:15528323|RGD:2303400 |
Molecular Function | GO:0042803 | protein homodimerization activity | GREM1 | IPI | UniProtKB:O60565 | Human | PMID:27036124 |
Molecular Function | GO:0048018 | receptor ligand activity | Grem1 | IPI | UniProtKB:P35918 | Mouse | MGI:MGI:4845816|PMID:20660291 |
Molecular Function | GO:0030297 | transmembrane receptor protein tyrosine kinase activator activity | Grem1 | IDA | Mouse | MGI:MGI:4845816|PMID:20660291 | |
Molecular Function | GO:0043184 | vascular endothelial growth factor receptor 2 binding | Grem1 | IPI | UniProtKB:P35968-2 | Mouse | MGI:MGI:4845816|PMID:20660291 |
Cellular Component | GO:0009986 | cell surface | Grem1 | IDA | Mouse | MGI:MGI:3834346|PMID:17077323 | |
Cellular Component | GO:0009986 | cell surface | Grem1 | IDA | Rat | PMID:10722723|RGD:2303398 | |
Cellular Component | GO:0062023 | collagen-containing extracellular matrix | GREM1 | HDA | Human | PMID:28327460 | |
Cellular Component | GO:0062023 | collagen-containing extracellular matrix | GREM1 | HDA | Human | PMID:25037231 | |
Cellular Component | GO:0005615 | extracellular space | Grem1 | IDA | Mouse | MGI:MGI:3834346|PMID:17077323 | |
Cellular Component | GO:0005615 | extracellular space | Grem1 | IDA | Rat | PMID:10722723|RGD:2303398 | |
Biological Process | GO:0001525 | angiogenesis | Grem1 | IDA | Mouse | PMID:18505784 | |
Biological Process | GO:0009887 | animal organ morphogenesis | Grem1 | IMP | MGI:MGI:1856289 | Mouse | PMID:15198975 |
Biological Process | GO:0006915 | apoptotic process | Grem1 | IEP | Rat | PMID:9234736|RGD:69808 | |
Biological Process | GO:0055007 | cardiac muscle cell differentiation | Grem1 | IDA | Mouse | MGI:MGI:5315691|PMID:18545679 | |
Biological Process | GO:0060379 | cardiac muscle cell myoblast differentiation | Grem1 | IDA | Mouse | MGI:MGI:5315691|PMID:18545679 | |
Biological Process | GO:0002042 | cell migration involved in sprouting angiogenesis | Grem1 | IDA | Mouse | MGI:MGI:3834346|PMID:17077323 | |
Biological Process | GO:0002042 | cell migration involved in sprouting angiogenesis | Grem1 | IDA | Mouse | MGI:MGI:4845816|PMID:20660291 | |
Biological Process | GO:0000902 | cell morphogenesis | GREM1 | IDA | Human | PMID:16545136 | |
Biological Process | GO:0007267 | cell-cell signaling | Grem1 | IMP | MGI:MGI:3046937 | Mouse | PMID:15201225 |
Biological Process | GO:0030199 | collagen fibril organization | GREM1 | IMP | Human | PMID:15539560 | |
Biological Process | GO:0048263 | determination of dorsal identity | GREM1 | IMP | Human | PMID:9660951 | |
Biological Process | GO:0030326 | embryonic limb morphogenesis | Grem1 | IMP | MGI:MGI:3054923 | Mouse | PMID:12808456 |
Biological Process | GO:0043542 | endothelial cell migration | Grem1 | IDA | Mouse | MGI:MGI:3834346|PMID:17077323 | |
Biological Process | GO:0060173 | limb development | GREM1 | IMP | Human | PMID:10556075 | |
Biological Process | GO:0003337 | mesenchymal to epithelial transition involved in metanephros morphogenesis | Grem1 | IDA | Mouse | MGI:MGI:3714585|PMID:17522159 | |
Biological Process | GO:0043066 | negative regulation of apoptotic process | GREM1 | IMP | Human | PMID:10556075 | |
Biological Process | GO:0030514 | negative regulation of BMP signaling pathway | GREM1 | IDA | Human | PMID:15539560 | |
Biological Process | GO:0030514 | negative regulation of BMP signaling pathway | GREM1 | IMP | Human | PMID:16816361 | |
Biological Process | GO:0030514 | negative regulation of BMP signaling pathway | GREM1 | IMP | Human | PMID:27036124 | |
Biological Process | GO:0030514 | negative regulation of BMP signaling pathway | Grem1 | IMP | MGI:MGI:3046937 | Mouse | PMID:17522159 |
Biological Process | GO:0030502 | negative regulation of bone mineralization | GREM1 | IMP | Human | PMID:15539560 | |
Biological Process | GO:1900158 | negative regulation of bone mineralization involved in bone maturation | GREM1 | IMP | Human | PMID:15539560 | |
Biological Process | GO:0046851 | negative regulation of bone remodeling | GREM1 | IMP | Human | PMID:15539560 | |
Biological Process | GO:1900155 | negative regulation of bone trabecula formation | GREM1 | IMP | Human | PMID:15539560 | |
Biological Process | GO:0090090 | negative regulation of canonical Wnt signaling pathway | GREM1 | IDA | Human | PMID:15539560 | |
Biological Process | GO:0030308 | negative regulation of cell growth | Grem1 | IMP | Rat | PMID:9234736|RGD:69808 | |
Biological Process | GO:0032331 | negative regulation of chondrocyte differentiation | GREM1 | IMP | Human | PMID:10556075 | |
Biological Process | GO:0045892 | negative regulation of DNA-templated transcription | Grem1 | IMP | Mouse | MGI:MGI:3714585|PMID:17522159 | |
Biological Process | GO:0002689 | negative regulation of leukocyte chemotaxis | Grem1 | IDA | Rat | PMID:15528323|RGD:2303400 | |
Biological Process | GO:0090027 | negative regulation of monocyte chemotaxis | Grem1 | IDA | Rat | PMID:15528323|RGD:2303400 | |
Biological Process | GO:0045668 | negative regulation of osteoblast differentiation | GREM1 | IMP | Human | PMID:27036124 | |
Biological Process | GO:0045668 | negative regulation of osteoblast differentiation | Grem1 | IMP | Rat | PMID:27910957|RGD:38501075 | |
Biological Process | GO:0033689 | negative regulation of osteoblast proliferation | GREM1 | IMP | Human | PMID:15539560 | |
Biological Process | GO:0090291 | negative regulation of osteoclast proliferation | GREM1 | IMP | Human | PMID:15539560 | |
Biological Process | GO:0060394 | negative regulation of pathway-restricted SMAD protein phosphorylation | GREM1 | IDA | Human | PMID:15539560 | |
Biological Process | GO:0045766 | positive regulation of angiogenesis | Grem1 | IMP | Mouse | MGI:MGI:3834346|PMID:17077323 | |
Biological Process | GO:0045766 | positive regulation of angiogenesis | Grem1 | IMP | Rat | PMID:17077323|RGD:8553524 | |
Biological Process | GO:0090190 | positive regulation of branching involved in ureteric bud morphogenesis | Grem1 | IDA | Mouse | MGI:MGI:3714585|PMID:17522159 | |
Biological Process | GO:0090190 | positive regulation of branching involved in ureteric bud morphogenesis | Grem1 | IDA | Mouse | PMID:21281623 | |
Biological Process | GO:0090190 | positive regulation of branching involved in ureteric bud morphogenesis | Grem1 | IGI | MGI:MGI:88180 | Mouse | PMID:17522159 |
Biological Process | GO:0008284 | positive regulation of cell population proliferation | GREM1 | IDA | Human | PMID:16545136 | |
Biological Process | GO:0045893 | positive regulation of DNA-templated transcription | Grem1 | IDA | Mouse | MGI:MGI:3714585|PMID:17522159 | |
Biological Process | GO:0051092 | positive regulation of NF-kappaB transcription factor activity | Grem1 | IDA | Mouse | PMID:18505784 | |
Biological Process | GO:1901224 | positive regulation of NIK/NF-kappaB signaling | Grem1 | IDA | Mouse | PMID:18505784 | |
Biological Process | GO:1900086 | positive regulation of peptidyl-tyrosine autophosphorylation | Grem1 | IDA | Mouse | MGI:MGI:4845816|PMID:20660291 | |
Biological Process | GO:0061098 | positive regulation of protein tyrosine kinase activity | Grem1 | IDA | Mouse | MGI:MGI:3834346|PMID:17077323 | |
Biological Process | GO:0002092 | positive regulation of receptor internalization | Grem1 | IDA | Mouse | MGI:MGI:4845816|PMID:20660291 | |
Biological Process | GO:2000273 | positive regulation of signaling receptor activity | Grem1 | IDA | Mouse | MGI:MGI:4845816|PMID:20660291 | |
Biological Process | GO:0051973 | positive regulation of telomerase activity | GREM1 | IDA | Human | PMID:16545136 | |
Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II | Grem1 | IDA | Mouse | MGI:MGI:5318033|PMID:12135612 | |
Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II | Grem1 | IDA | Mouse | MGI:MGI:5315691|PMID:18545679 | |
Biological Process | GO:0009954 | proximal/distal pattern formation | Grem1 | IMP | MGI:MGI:3054923 | Mouse | PMID:12808456 |
Biological Process | GO:0010717 | regulation of epithelial to mesenchymal transition | GREM1 | IMP | Human | PMID:16816361 | |
Biological Process | GO:0051893 | regulation of focal adhesion assembly | Grem1 | IDA | Mouse | MGI:MGI:3834346|PMID:17077323 | |
Biological Process | GO:0007165 | signal transduction | Grem1 | IDA | Mouse | MGI:MGI:4845816|PMID:20660291 | |
Biological Process | GO:0060676 | ureteric bud formation | Grem1 | IDA | Mouse | MGI:MGI:3714585|PMID:17522159 |
EXP Inferred from experiment |
IDA Inferred from direct assay |
IEP Inferred from expression pattern |
IGI Inferred from genetic interaction |
IMP Inferred from mutant phenotype |
IPI Inferred from physical interaction |
HTP Inferred from High Throughput Experiment |
HDA Inferred from High Throughput Direct Assay |
HMP Inferred from High Throughput Mutant Phenotype |
HGI Inferred from High Throughput Genetic Interaction |
HEP Inferred from High Throughput Expression Pattern |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 12/10/2024 MGI 6.24 |
![]() |
|