Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GRHPR
  • Mouse genes Grhpr
  • Rat genes Grhpr
  • Zfish genes grhpra,grhprb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Grhpr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031406	carboxylic acid binding	Grhpr	IPI	CHEBI:17180	Rat	PMID:2689175|RGD:1599320
Molecular Function	GO:0031406	carboxylic acid binding	Grhpr	IPI	CHEBI:36655	Rat	PMID:2689175|RGD:1599320
Molecular Function	GO:0008465	glycerate dehydrogenase activity	GRHPR	IDA		Human	PMID:10484776
Molecular Function	GO:0008465	glycerate dehydrogenase activity	Grhpr	IDA		Rat	PMID:2689175|RGD:1599320
Molecular Function	GO:0030267	glyoxylate reductase (NADP+) activity	GRHPR	IDA		Human	PMID:10484776
Molecular Function	GO:0030267	glyoxylate reductase (NADP+) activity	GRHPR	IDA		Human	PMID:10524214
Molecular Function	GO:0030267	glyoxylate reductase (NADP+) activity	Grhpr	IDA		Rat	PMID:2689175|RGD:1599320
Molecular Function	GO:0016618	hydroxypyruvate reductase activity	GRHPR	IDA		Human	PMID:10484776
Molecular Function	GO:0016618	hydroxypyruvate reductase activity	GRHPR	IDA		Human	PMID:10524214
Molecular Function	GO:0016618	hydroxypyruvate reductase activity	GRHPR	IDA		Human	PMID:17510093
Molecular Function	GO:0016618	hydroxypyruvate reductase activity	Grhpr	IDA		Rat	PMID:2689175|RGD:1599320
Molecular Function	GO:0051287	NAD binding	Grhpr	IDA		Rat	PMID:2689175|RGD:1599320
Molecular Function	GO:0050661	NADP binding	Grhpr	IDA		Rat	PMID:2689175|RGD:1599320
Molecular Function	GO:0070402	NADPH binding	GRHPR	IDA		Human	PMID:16756993
Molecular Function	GO:0005515	protein binding	GRHPR	IPI	UniProtKB:Q9UHI7	Human	PMID:23599041
Molecular Function	GO:0042803	protein homodimerization activity	GRHPR	IDA		Human	PMID:16756993
Cellular Component	GO:1902494	catalytic complex	GRHPR	IDA		Human	PMID:16756993
Cellular Component	GO:0005737	cytoplasm	GRHPR	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005829	cytosol	Grhpr	IDA		Rat	PMID:2689175|RGD:1599320
Cellular Component	GO:0070062	extracellular exosome	GRHPR	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	GRHPR	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	GRHPR	HDA		Human	PMID:23533145
Biological Process	GO:0043648	dicarboxylic acid metabolic process	Grhpr	IDA		Rat	PMID:2689175|RGD:1599320
Biological Process	GO:0046487	glyoxylate metabolic process	GRHPR	IDA		Human	PMID:10484776
Biological Process	GO:0046487	glyoxylate metabolic process	GRHPR	IDA		Human	PMID:10524214

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern