Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Gria4

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes GRIA4
- Mouse genes Gria4
- Rat genes Gria4
- Zfish genes gria4a,gria4b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gria4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004971	AMPA glutamate receptor activity	GRIA4	IDA		Human	PMID:21172611
Molecular Function	GO:0004971	AMPA glutamate receptor activity	Gria4	IMP		Rat	PMID:2166337\|RGD:728438
Molecular Function	GO:0042802	identical protein binding	Gria4	IPI	UniProtKB:P19493-2	Rat	PMID:20457909\|RGD:13432258
Molecular Function	GO:0042802	identical protein binding	Gria4	IPI	UniProtKB:P19493	Rat	PMID:21317873\|RGD:8553419
Molecular Function	GO:0042802	identical protein binding	Gria4	IPI	UniProtKB:P19493	Rat	PMID:22959625\|RGD:13432309
Molecular Function	GO:0004970	ionotropic glutamate receptor activity	Gria4	IDA		Rat	PMID:19102704\|RGD:8554524
Molecular Function	GO:0004970	ionotropic glutamate receptor activity	gria4a	IMP	ZFIN:ZDB-GENO-220909-6	Zfish	PMID:33975920
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GRIA4	IDA		Human	PMID:12670305
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GRIA4	IMP		Human	PMID:12670305
Molecular Function	GO:0005515	protein binding	Gria4	IPI	PR:P23819	Mouse	PMID:15883194
Molecular Function	GO:0005515	protein binding	Gria4	IPI	PR:P23818	Mouse	PMID:15883194
Molecular Function	GO:0005515	protein binding	Gria4	IPI	PR:Q62108	Mouse	PMID:15883194
Molecular Function	GO:0005515	protein binding	Gria4	IPI	UniProtKB:P97879	Rat	PMID:11891216\|RGD:8553442
Molecular Function	GO:0005515	protein binding	Gria4	IPI	UniProtKB:P97879	Rat	PMID:11931740\|RGD:619588
Molecular Function	GO:0005515	protein binding	Gria4	IPI	UniProtKB:P63319	Rat	PMID:12471040\|RGD:8554457
Molecular Function	GO:0005515	protein binding	Gria4	IPI	UniProtKB:P49185	Rat	PMID:18188153\|RGD:8553460
Molecular Function	GO:0005515	protein binding	Gria4	IPI	UniProtKB:Q8VHW8	Rat	PMID:18817736\|RGD:8554789
Molecular Function	GO:0005515	protein binding	Gria4	IPI	UniProtKB:Q8VHW8	Rat	PMID:19234459\|RGD:8554069
Molecular Function	GO:0005515	protein binding	Gria4	IPI	UniProtKB:P19491-2	Rat	PMID:26966189\|RGD:13432296
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Gria4	IMP		Mouse	PMID:21857658
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Gria4	IDA		Mouse	PMID:21857658
Cellular Component	GO:0032281	AMPA glutamate receptor complex	Gria4	IDA		Mouse	PMID:15883194
Cellular Component	GO:0032281	AMPA glutamate receptor complex	Gria4	IDA		Mouse	PMID:22632720
Cellular Component	GO:0032281	AMPA glutamate receptor complex	Gria4	IDA		Rat	PMID:19265014\|RGD:8554136
Cellular Component	GO:0030425	dendrite	Gria4	IMP		Rat	PMID:11036266\|RGD:8554601
Cellular Component	GO:0030425	dendrite	Gria4	IDA		Rat	PMID:15844209\|RGD:1642495
Cellular Component	GO:0030425	dendrite	gria4a	IDA		Zfish	PMID:15885223
Cellular Component	GO:0043197	dendritic spine	Gria4	IDA		Rat	PMID:20032460\|RGD:12907563
Cellular Component	GO:1903561	extracellular vesicle	GRIA4	HDA		Human	PMID:24769233
Cellular Component	GO:0098978	glutamatergic synapse	Gria4	IMP		Mouse	PMID:21857658
Cellular Component	GO:0098978	glutamatergic synapse	Gria4	IDA		Mouse	PMID:21857658
Cellular Component	GO:0098978	glutamatergic synapse	Gria4	IDA		Rat	PMID:11113346\|RGD:155230762
Cellular Component	GO:0098978	glutamatergic synapse	Gria4	IDA		Rat	PMID:15610164\|RGD:13702224
Cellular Component	GO:0032983	kainate selective glutamate receptor complex	Gria4	IDA		Rat	PMID:20107073\|RGD:8554240
Cellular Component	GO:0043025	neuronal cell body	Gria4	IDA		Rat	PMID:11036266\|RGD:8554601
Cellular Component	GO:0043025	neuronal cell body	Gria4	IDA		Rat	PMID:15844209\|RGD:1642495
Cellular Component	GO:0043025	neuronal cell body	Gria4	IDA		Rat	PMID:20032460\|RGD:12907563
Cellular Component	GO:0043025	neuronal cell body	gria4a	IDA		Zfish	PMID:15885223
Cellular Component	GO:0014069	postsynaptic density	Gria4	IDA		Rat	PMID:11036266\|RGD:8554601
Cellular Component	GO:0098839	postsynaptic density membrane	Gria4	IDA		Rat	PMID:11113346\|RGD:155230762
Cellular Component	GO:0048787	presynaptic active zone membrane	Gria4	IDA		Rat	PMID:15610164\|RGD:13702224
Cellular Component	GO:0045202	synapse	Gria4	IDA		Mouse	PMID:22632720
Cellular Component	GO:0045202	synapse	Gria4	IMP		Rat	PMID:11036266\|RGD:8554601
Cellular Component	GO:0043195	terminal bouton	Gria4	IDA		Rat	PMID:15844209\|RGD:1642495
Biological Process	GO:0007268	chemical synaptic transmission	Gria4	IMP		Rat	PMID:2166337\|RGD:728438
Biological Process	GO:0008347	glial cell migration	gria4a	IMP	ZFIN:ZDB-GENO-220909-6	Zfish	PMID:33975920
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Gria4	IMP		Rat	PMID:11036266\|RGD:8554601
Biological Process	GO:0034392	negative regulation of smooth muscle cell apoptotic process	GRIA4	IGI	RNAcentral:URS00003E47B1_9606	Human	PMID:32151690
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	Gria4	IMP		Rat	PMID:11036266\|RGD:8554601
Biological Process	GO:0060992	response to fungicide	Gria4	IEP		Rat	PMID:19591855\|RGD:2325972

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.