Source |
Alliance of Genome Resources |
Category | ID | Classification term | Gene | Evidence | Inferred from | Organism | Reference |
---|---|---|---|---|---|---|---|
Molecular Function | GO:0005234 | extracellularly glutamate-gated ion channel activity | GRIK2 | IMP | Human | PMID:28180184 | |
Molecular Function | GO:0008066 | glutamate receptor activity | Grik2 | IDA | Rat | PMID:10627597|RGD:8553571 | |
Molecular Function | GO:0042802 | identical protein binding | Grik2 | IDA | Rat | PMID:1648177|RGD:69852 | |
Molecular Function | GO:0042802 | identical protein binding | Grik2 | IPI | RGD:2733 | Rat | PMID:1648177|RGD:69852 |
Molecular Function | GO:0042802 | identical protein binding | Grik2 | IPI | UniProtKB:P42260 | Rat | PMID:17115050|RGD:13432262 |
Molecular Function | GO:0042802 | identical protein binding | Grik2 | IPI | UniProtKB:P42260 | Rat | PMID:19465914|RGD:13432328 |
Molecular Function | GO:0042802 | identical protein binding | Grik2 | IPI | UniProtKB:P42260 | Rat | PMID:19617541|RGD:13432236 |
Molecular Function | GO:0042802 | identical protein binding | Grik2 | IPI | UniProtKB:P42260 | Rat | PMID:20404149|RGD:13432256 |
Molecular Function | GO:0042802 | identical protein binding | Grik2 | IPI | UniProtKB:P42260 | Rat | PMID:25119039|RGD:13432242 |
Molecular Function | GO:0004970 | ionotropic glutamate receptor activity | Grik2 | IMP | Mouse | MGI:MGI:3690189|PMID:16354929 | |
Molecular Function | GO:0004970 | ionotropic glutamate receptor activity | Grik2 | IDA | Mouse | MGI:MGI:6414684|PMID:31474366 | |
Molecular Function | GO:0015277 | kainate selective glutamate receptor activity | GRIK2 | IDA | Human | PMID:15537878 | |
Molecular Function | GO:0015277 | kainate selective glutamate receptor activity | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:10704492 |
Molecular Function | GO:0015277 | kainate selective glutamate receptor activity | Grik2 | IDA | Mouse | PMID:1310861 | |
Molecular Function | GO:0015277 | kainate selective glutamate receptor activity | Grik2 | IDA | Mouse | PMID:15483117 | |
Molecular Function | GO:0015277 | kainate selective glutamate receptor activity | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:15509753 |
Molecular Function | GO:0015277 | kainate selective glutamate receptor activity | Grik2 | IGI | MGI:MGI:95814 | Mouse | PMID:11985817 |
Molecular Function | GO:0015277 | kainate selective glutamate receptor activity | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:12223554 |
Molecular Function | GO:0015277 | kainate selective glutamate receptor activity | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:11985817 |
Molecular Function | GO:0015277 | kainate selective glutamate receptor activity | Grik2 | IDA | Mouse | PMID:12151522 | |
Molecular Function | GO:0015277 | kainate selective glutamate receptor activity | Grik2 | IMP | Mouse | PMID:12223554 | |
Molecular Function | GO:0015277 | kainate selective glutamate receptor activity | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:9580260 |
Molecular Function | GO:0015277 | kainate selective glutamate receptor activity | Grik2 | IGI | MGI:MGI:95818 | Mouse | PMID:1310861 |
Molecular Function | GO:0015277 | kainate selective glutamate receptor activity | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:9880586 |
Molecular Function | GO:0015277 | kainate selective glutamate receptor activity | Grik2 | IDA | Rat | PMID:1648177|RGD:69852 | |
Molecular Function | GO:0099507 | ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential | Grik2 | IDA | Mouse | PMID:17620617 | |
Molecular Function | GO:0099507 | ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential | Grik2 | IEP | Mouse | PMID:17620617 | |
Molecular Function | GO:0099507 | ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential | Grik2 | IMP | Mouse | PMID:17620617 | |
Molecular Function | GO:0030165 | PDZ domain binding | Grik2 | IPI | UniProtKB:P31016 | Rat | PMID:1127911|RGD:8553546 |
Molecular Function | GO:0030165 | PDZ domain binding | Grik2 | IPI | UniProtKB:Q62696 | Rat | PMID:1127911|RGD:8553546 |
Molecular Function | GO:0030165 | PDZ domain binding | Grik2 | IPI | UniProtKB:P31016 | Rat | PMID:9808460|RGD:8554157 |
Molecular Function | GO:0005515 | protein binding | Grik2 | IPI | UniProtKB:P21279|UniProtKB:P31016 | Mouse | MGI:MGI:3690189|PMID:16354929 |
Molecular Function | GO:0005515 | protein binding | Grik2 | IPI | PR:Q8BNJ6 | Mouse | PMID:21734292 |
Molecular Function | GO:0005515 | protein binding | Grik2 | IPI | PR:Q8R4I7 | Mouse | PMID:21734292 |
Molecular Function | GO:0005515 | protein binding | Grik2 | IPI | PR:Q8BMF5 | Mouse | PMID:12954862 |
Molecular Function | GO:0005515 | protein binding | Grik2 | IPI | RGD:1307709 | Rat | PMID:12597860|RGD:152995391 |
Molecular Function | GO:0005515 | protein binding | Grik2 | IPI | RGD:621667 | Rat | PMID:12597860|RGD:152995391 |
Molecular Function | GO:0005515 | protein binding | Grik2 | IPI | RGD:68424 | Rat | PMID:12597860|RGD:152995391 |
Molecular Function | GO:0005515 | protein binding | Grik2 | IPI | UniProtKB:Q8K430 | Rat | PMID:17062563|RGD:8553595 |
Molecular Function | GO:0005515 | protein binding | Grik2 | IPI | UniProtKB:O70260 | Rat | PMID:17486098|RGD:1642482 |
Molecular Function | GO:0005515 | protein binding | Grik2 | IPI | UniProtKB:P63281 | Rat | PMID:17486098|RGD:1642482 |
Molecular Function | GO:0005515 | protein binding | Grik2 | IPI | UniProtKB:Q5I0H3 | Rat | PMID:17486098|RGD:1642482 |
Molecular Function | GO:0005515 | protein binding | Grik2 | IPI | UniProtKB:Q5I0H3 | Rat | PMID:22089239|RGD:13432300 |
Molecular Function | GO:0005515 | protein binding | Grik2 | IPI | UniProtKB:Q5I0H3 | Rat | PMID:22483987|RGD:8554830 |
Molecular Function | GO:0005515 | protein binding | Grik2 | IPI | UniProtKB:Q66HA1 | Rat | PMID:22483987|RGD:8554830 |
Molecular Function | GO:0005515 | protein binding | Grik2 | IPI | UniProtKB:P31016 | Rat | PMID:9808460|RGD:8554157 |
Molecular Function | GO:0097110 | scaffold protein binding | Grik2 | IDA | Rat | PMID:12597860|RGD:152995391 | |
Molecular Function | GO:0000149 | SNARE binding | Grik2 | IPI | RGD:69437 | Rat | PMID:12597860|RGD:152995391 |
Molecular Function | GO:1904315 | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Grik2 | IDA | Mouse | PMID:22345355 | |
Molecular Function | GO:1904315 | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Grik2 | IMP | Mouse | PMID:22345355 | |
Molecular Function | GO:1904315 | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Grik2 | EXP | Mouse | PMID:22345355 | |
Molecular Function | GO:1904315 | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Grik2 | IDA | Mouse | PMID:9580260 | |
Molecular Function | GO:1904315 | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Grik2 | IMP | Mouse | PMID:9580260 | |
Molecular Function | GO:0031624 | ubiquitin conjugating enzyme binding | Grik2 | IPI | RGD:3926 | Rat | PMID:17486098|RGD:1642482 |
Molecular Function | GO:0031625 | ubiquitin protein ligase binding | Grik2 | IPI | RGD:708413 | Rat | PMID:17486098|RGD:1642482 |
Cellular Component | GO:0030424 | axon | Grik2 | IDA | Rat | PMID:15844209|RGD:1642495 | |
Cellular Component | GO:0030425 | dendrite | Grik2 | IDA | Rat | PMID:16360275|RGD:1642473 | |
Cellular Component | GO:0030425 | dendrite | Grik2 | IDA | Rat | PMID:17486098|RGD:1642482 | |
Cellular Component | GO:0030425 | dendrite | Grik2 | IDA | Rat | PMID:9808460|RGD:8554157 | |
Cellular Component | GO:0032839 | dendrite cytoplasm | Grik2 | IDA | Rat | PMID:15844209|RGD:1642495 | |
Cellular Component | GO:0098978 | glutamatergic synapse | Grik2 | IDA | Mouse | PMID:17620617 | |
Cellular Component | GO:0098978 | glutamatergic synapse | Grik2 | IEP | Mouse | PMID:17620617 | |
Cellular Component | GO:0098978 | glutamatergic synapse | Grik2 | IMP | Mouse | PMID:17620617 | |
Cellular Component | GO:0098978 | glutamatergic synapse | Grik2 | IMP | Mouse | PMID:27346345 | |
Cellular Component | GO:0098978 | glutamatergic synapse | Grik2 | IDA | Mouse | PMID:27346345 | |
Cellular Component | GO:0098686 | hippocampal mossy fiber to CA3 synapse | Grik2 | EXP | Mouse | PMID:22345355 | |
Cellular Component | GO:0098686 | hippocampal mossy fiber to CA3 synapse | Grik2 | IDA | Mouse | PMID:22345355 | |
Cellular Component | GO:0098686 | hippocampal mossy fiber to CA3 synapse | Grik2 | IMP | Mouse | PMID:22345355 | |
Cellular Component | GO:0098686 | hippocampal mossy fiber to CA3 synapse | Grik2 | IDA | Mouse | PMID:9580260 | |
Cellular Component | GO:0098686 | hippocampal mossy fiber to CA3 synapse | Grik2 | IMP | Mouse | PMID:9580260 | |
Cellular Component | GO:0008328 | ionotropic glutamate receptor complex | Grik2 | IDA | Rat | PMID:10627597|RGD:8553571 | |
Cellular Component | GO:0032983 | kainate selective glutamate receptor complex | Grik2 | IPI | PR:Q8BMF5 | Mouse | PMID:12954862 |
Cellular Component | GO:0032983 | kainate selective glutamate receptor complex | Grik2 | IPI | PR:Q61626 | Mouse | PMID:17174564 |
Cellular Component | GO:0032983 | kainate selective glutamate receptor complex | Grik2 | IPI | PR:Q61626 | Mouse | PMID:12954862 |
Cellular Component | GO:0032983 | kainate selective glutamate receptor complex | Grik2 | IPI | PR:Q60934 | Mouse | PMID:17174564 |
Cellular Component | GO:0016020 | membrane | Grik2 | IDA | Mouse | PMID:12954862 | |
Cellular Component | GO:0097471 | mossy fiber rosette | Grik2 | IDA | Mouse | PMID:27346345 | |
Cellular Component | GO:0097471 | mossy fiber rosette | Grik2 | IMP | Mouse | PMID:27346345 | |
Cellular Component | GO:0043025 | neuronal cell body | Grik2 | IDA | Mouse | PMID:9141074 | |
Cellular Component | GO:0043204 | perikaryon | Grik2 | IDA | Rat | PMID:15844209|RGD:1642495 | |
Cellular Component | GO:0005886 | plasma membrane | Grik2 | IDA | Rat | PMID:9808460|RGD:8554157 | |
Cellular Component | GO:0014069 | postsynaptic density | Grik2 | IDA | Mouse | PMID:21734292 | |
Cellular Component | GO:0045211 | postsynaptic membrane | Grik2 | IDA | Mouse | PMID:14724198 | |
Cellular Component | GO:0045211 | postsynaptic membrane | Grik2 | IDA | Mouse | PMID:27346345 | |
Cellular Component | GO:0045211 | postsynaptic membrane | Grik2 | IMP | Mouse | PMID:27346345 | |
Cellular Component | GO:0042734 | presynaptic membrane | Grik2 | IDA | Mouse | PMID:14724198 | |
Cellular Component | GO:0042734 | presynaptic membrane | Grik2 | IDA | Mouse | PMID:11985817 | |
Cellular Component | GO:0045202 | synapse | Grik2 | IDA | Mouse | PMID:21734292 | |
Cellular Component | GO:0045202 | synapse | Grik2 | IDA | Rat | PMID:17486098|RGD:1642482 | |
Cellular Component | GO:0043195 | terminal bouton | Grik2 | IDA | Rat | PMID:15844209|RGD:1642495 | |
Biological Process | GO:0001662 | behavioral fear response | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:15673679 |
Biological Process | GO:0007268 | chemical synaptic transmission | Grik2 | IGI | MGI:MGI:95814 | Mouse | PMID:15928066 |
Biological Process | GO:0007268 | chemical synaptic transmission | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:15928066 |
Biological Process | GO:0007268 | chemical synaptic transmission | Grik2 | IMP | Rat | PMID:1648177|RGD:69852 | |
Biological Process | GO:0120169 | detection of cold stimulus involved in thermoception | Grik2 | IMP | Mouse | MGI:MGI:6414684|PMID:31474366 | |
Biological Process | GO:0120169 | detection of cold stimulus involved in thermoception | grik2 | IMP | ZFIN:ZDB-GENO-230302-7 | Zfish | PMID:36011351 |
Biological Process | GO:0060079 | excitatory postsynaptic potential | Grik2 | IGI | MGI:MGI:95814 | Mouse | PMID:11985817 |
Biological Process | GO:0060079 | excitatory postsynaptic potential | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:11069933 |
Biological Process | GO:0060079 | excitatory postsynaptic potential | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:14724198 |
Biological Process | GO:0060080 | inhibitory postsynaptic potential | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:9880586 |
Biological Process | GO:0060080 | inhibitory postsynaptic potential | Grik2 | IGI | MGI:MGI:99402 | Mouse | PMID:10704492 |
Biological Process | GO:0060080 | inhibitory postsynaptic potential | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:12223554 |
Biological Process | GO:0060080 | inhibitory postsynaptic potential | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:10704492 |
Biological Process | GO:0060080 | inhibitory postsynaptic potential | Grik2 | IGI | MGI:MGI:95814 | Mouse | PMID:11144357 |
Biological Process | GO:0006874 | intracellular calcium ion homeostasis | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:16219388 |
Biological Process | GO:0050804 | modulation of chemical synaptic transmission | GRIK2 | IDA | Human | PMID:15537878 | |
Biological Process | GO:0098815 | modulation of excitatory postsynaptic potential | Grik2 | IMP | Rat | PMID:12597860|RGD:152995391 | |
Biological Process | GO:0043524 | negative regulation of neuron apoptotic process | Grik2 | IGI | MGI:MGI:95819 | Mouse | PMID:10479699 |
Biological Process | GO:0051967 | negative regulation of synaptic transmission, glutamatergic | Grik2 | IGI | MGI:MGI:95814 | Mouse | PMID:11985817 |
Biological Process | GO:0051967 | negative regulation of synaptic transmission, glutamatergic | Grik2 | IDA | Rat | PMID:16420445|RGD:8554693 | |
Biological Process | GO:0051402 | neuron apoptotic process | Grik2 | IGI | MGI:MGI:95819 | Mouse | PMID:10479699 |
Biological Process | GO:0051402 | neuron apoptotic process | Grik2 | IMP | Rat | PMID:11152698|RGD:8554109 | |
Biological Process | GO:0019228 | neuronal action potential | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:15539395 |
Biological Process | GO:0043525 | positive regulation of neuron apoptotic process | Grik2 | IMP | Rat | PMID:17639597|RGD:2316528 | |
Biological Process | GO:0050806 | positive regulation of synaptic transmission | GRIK2 | IMP | Human | PMID:15537878 | |
Biological Process | GO:0099171 | presynaptic modulation of chemical synaptic transmission | Grik2 | IGI | MGI:MGI:95814 | Mouse | PMID:11985817 |
Biological Process | GO:0043113 | receptor clustering | Grik2 | IDA | Rat | PMID:9808460|RGD:8554157 | |
Biological Process | GO:0046328 | regulation of JNK cascade | Grik2 | IMP | Rat | PMID:11152698|RGD:8554109 | |
Biological Process | GO:0048169 | regulation of long-term neuronal synaptic plasticity | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:16219388 |
Biological Process | GO:0048169 | regulation of long-term neuronal synaptic plasticity | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:15673679 |
Biological Process | GO:0048169 | regulation of long-term neuronal synaptic plasticity | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:12947409 |
Biological Process | GO:0048169 | regulation of long-term neuronal synaptic plasticity | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:11182092 |
Biological Process | GO:0042391 | regulation of membrane potential | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:10704492 |
Biological Process | GO:0042391 | regulation of membrane potential | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:9490692 |
Biological Process | GO:0042391 | regulation of membrane potential | Grik2 | IGI | MGI:MGI:95818 | Mouse | PMID:1310861 |
Biological Process | GO:0042391 | regulation of membrane potential | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:15513934 |
Biological Process | GO:0042391 | regulation of membrane potential | Grik2 | IMP | Mouse | PMID:12223554 | |
Biological Process | GO:0042391 | regulation of membrane potential | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:15509753 |
Biological Process | GO:0042391 | regulation of membrane potential | Grik2 | IDA | Mouse | PMID:12151522 | |
Biological Process | GO:0042391 | regulation of membrane potential | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:16219388 |
Biological Process | GO:0042391 | regulation of membrane potential | Grik2 | IDA | Mouse | PMID:1310861 | |
Biological Process | GO:0048172 | regulation of short-term neuronal synaptic plasticity | GRIK2 | IMP | Human | PMID:15537878 | |
Biological Process | GO:0048172 | regulation of short-term neuronal synaptic plasticity | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:11182092 |
Biological Process | GO:0009409 | response to cold | grik2 | IMP | ZFIN:ZDB-GENO-230302-7 | Zfish | PMID:36011351 |
Biological Process | GO:0035249 | synaptic transmission, glutamatergic | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:15509753 |
Biological Process | GO:0035249 | synaptic transmission, glutamatergic | Grik2 | IMP | MGI:MGI:1857979 | Mouse | PMID:9580260 |
EXP Inferred from experiment |
IDA Inferred from direct assay |
IEP Inferred from expression pattern |
IGI Inferred from genetic interaction |
IMP Inferred from mutant phenotype |
IPI Inferred from physical interaction |
HTP Inferred from High Throughput Experiment |
HDA Inferred from High Throughput Direct Assay |
HMP Inferred from High Throughput Mutant Phenotype |
HGI Inferred from High Throughput Genetic Interaction |
HEP Inferred from High Throughput Expression Pattern |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/05/2024 MGI 6.24 |
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