Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GRIK3
  • Mouse genes Grik3
  • Rat genes Grik3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Grik3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001640	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity	GRIK3	IDA		Human	PMID:9144652
Molecular Function	GO:0008066	glutamate receptor activity	Grik3	IDA		Rat	PMID:9390526|RGD:728668
Molecular Function	GO:0004970	ionotropic glutamate receptor activity	GRIK3	IDA		Human	PMID:11124978
Molecular Function	GO:0004970	ionotropic glutamate receptor activity	Grik3	IDA		Rat	PMID:11124978|RGD:8553521
Molecular Function	GO:0004970	ionotropic glutamate receptor activity	Grik3	IMP		Rat	PMID:21907808|RGD:8553493
Molecular Function	GO:0015277	kainate selective glutamate receptor activity	GRIK3	IDA		Human	PMID:7719709
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	Grik3	IDA		Mouse	PMID:17620617
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	Grik3	IEP		Mouse	PMID:17620617
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	Grik3	IMP		Mouse	PMID:17620617
Molecular Function	GO:0005515	protein binding	Grik3	IPI	PR:P39087-1	Mouse	PMID:15805114
Molecular Function	GO:0005515	protein binding	Grik3	IPI	PR:P39087-2	Mouse	PMID:15805114
Cellular Component	GO:0030424	axon	Grik3	IDA		Rat	PMID:15844209|RGD:1642495
Cellular Component	GO:0030425	dendrite	Grik3	IDA		Rat	PMID:16360275|RGD:1642473
Cellular Component	GO:0030425	dendrite	Grik3	IDA		Rat	PMID:16420445|RGD:8554693
Cellular Component	GO:0032839	dendrite cytoplasm	Grik3	IDA		Rat	PMID:15844209|RGD:1642495
Cellular Component	GO:0098978	glutamatergic synapse	Grik3	IDA		Mouse	PMID:17620617
Cellular Component	GO:0098978	glutamatergic synapse	Grik3	IEP		Mouse	PMID:17620617
Cellular Component	GO:0098978	glutamatergic synapse	Grik3	IMP		Mouse	PMID:17620617
Cellular Component	GO:0043204	perikaryon	Grik3	IDA		Rat	PMID:15844209|RGD:1642495
Cellular Component	GO:0005886	plasma membrane	GRIK3	IDA		Human	PMID:7719709
Cellular Component	GO:0005886	plasma membrane	Grik3	IDA		Mouse	PMID:15805114
Cellular Component	GO:0043195	terminal bouton	Grik3	IDA		Rat	PMID:15844209|RGD:1642495
Biological Process	GO:0007216	G protein-coupled glutamate receptor signaling pathway	GRIK3	IDA		Human	PMID:9144652
Biological Process	GO:0007215	glutamate receptor signaling pathway	GRIK3	IDA		Human	PMID:7719709
Biological Process	GO:0051967	negative regulation of synaptic transmission, glutamatergic	Grik3	IDA		Rat	PMID:16420445|RGD:8554693
Biological Process	GO:0042391	regulation of membrane potential	GRIK3	IDA		Human	PMID:11124978
Biological Process	GO:0042391	regulation of membrane potential	Grik3	IDA		Rat	PMID:11124978|RGD:8553521

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern