Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Grin2c

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes GRIN2C
- Mouse genes Grin2c
- Rat genes Grin2c
- Zfish genes grin2ca,grin2cb
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Grin2c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0022849	glutamate-gated calcium ion channel activity	GRIN2C	IDA		Human	PMID:26875626
Molecular Function	GO:0004970	ionotropic glutamate receptor activity	Grin2c	IDA		Rat	PMID:8428958\|RGD:728651
Molecular Function	GO:0005261	monoatomic cation channel activity	Grin2c	IMP	MGI:MGI:1928510	Mouse	PMID:9427357
Molecular Function	GO:0005261	monoatomic cation channel activity	Grin2c	IMP	MGI:MGI:1928301	Mouse	PMID:8756432
Molecular Function	GO:0005261	monoatomic cation channel activity	Grin2c	IDA		Rat	PMID:8428958\|RGD:728651
Molecular Function	GO:0004972	NMDA glutamate receptor activity	GRIN2C	IDA		Human	PMID:26919761
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin2c	IMP	MGI:MGI:1928510	Mouse	PMID:9512392
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin2c	IMP	MGI:MGI:1928301	Mouse	PMID:8756432
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin2c	IGI	RGD:2736	Mouse	PMID:7929101
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin2c	IMP	MGI:MGI:1928510	Mouse	PMID:9427357
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin2c	IGI	MGI:MGI:95819	Mouse	PMID:1377365
Molecular Function	GO:0004972	NMDA glutamate receptor activity	Grin2c	IDA		Rat	PMID:8428958\|RGD:728651
Molecular Function	GO:0030165	PDZ domain binding	Grin2c	IPI	RGD:68423	Rat	PMID:16606616\|RGD:1642375
Molecular Function	GO:0030165	PDZ domain binding	Grin2c	IPI	RGD:68424	Rat	PMID:16606616\|RGD:1642375
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:P31016	Human	PMID:11937501
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:P78352	Human	PMID:11937501
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q62936	Human	PMID:11937501
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q12959	Human	PMID:30126976
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:A0A0A0MR05	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:A0AVK6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:B7Z3E8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:D3DX41	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:O00472	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:O15273	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:O15534	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:O43482	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:O43741	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:O43829	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:O60237-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:O60830	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:O60902-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:O95674	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:P02458-1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:P06454-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:P10809	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:P15407	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:P19388	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:P24941	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:P36406	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:P41271-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:P47804-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:P49459	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:P54274-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:P62333	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:P62701	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q06323	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q06547-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q07869	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q13404	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q13573	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q13586	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q14117	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q14847-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q15382	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q1L5Z9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q3KNS6-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q3SXR2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q495U3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q496A3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q49A26-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q53FD0-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q5BJF6-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q5M9N0-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q5PSV4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q5SXH7-1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q5T0J7-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q5T447-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q5W111-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q658K8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q66PJ3-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q68G74	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q6GQQ9-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q6IN84-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q6PF05	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q6PHZ7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q6UY14-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q6ZMI0-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q6ZN54-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q6ZR37	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q7Z7F0-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q7Z7J5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q86WV5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q8IUR5-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q8N0U2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q8N0U6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q8NDH6-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q8NDP9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q8WTV1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q8WUD1-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q8WUX9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q8WVD3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q96CS2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q96FT7-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q96GL9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q96H12	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q96JB6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q96JL9-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q96LL4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q96LR2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q99743	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q9BPU6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q9BT25	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q9BXU0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q9H0X6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q9H2C1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q9H2G9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q9NP64	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q9NPC6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q9NR21-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q9NSI6-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q9NTN9-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q9NX94	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q9NZH6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q9P1Q0-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q9UJU6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q9ULD4-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q9UPQ4-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q9Y3D0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GRIN2C	IPI	UniProtKB:Q9Y6W6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Grin2c	IPI	PR:Q08509	Mouse	PMID:17018287
Molecular Function	GO:0005515	protein binding	Grin2c	IPI	PR:Q3UHD6	Mouse	PMID:21300787
Molecular Function	GO:0005515	protein binding	Grin2c	IPI	PR:P35438	Mouse	PMID:9458051
Molecular Function	GO:0005515	protein binding	Grin2c	IPI	UniProtKB:P35439	Mouse	PMID:7929101
Molecular Function	GO:0005515	protein binding	Grin2c	IPI	PR:P35438	Mouse	PMID:8595214
Molecular Function	GO:0005515	protein binding	Grin2c	IPI	UniProtKB:Q63ZW7	Rat	PMID:9647694\|RGD:8553765
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Grin2c	IDA		Mouse	PMID:8987814
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Grin2c	IMP		Mouse	PMID:8987814
Cellular Component	GO:0098978	glutamatergic synapse	Grin2c	IMP		Mouse	PMID:8987814
Cellular Component	GO:0098978	glutamatergic synapse	Grin2c	IDA		Mouse	PMID:8987814
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	GRIN2C	IDA		Human	PMID:26875626
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	GRIN2C	IDA		Human	PMID:26919761
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	Grin2c	IPI	UniProtKB:P35439	Mouse	PMID:7929101
Cellular Component	GO:0005886	plasma membrane	GRIN2C	IDA		Human	PMID:26875626
Cellular Component	GO:0005886	plasma membrane	GRIN2C	IDA		Human	PMID:26919761
Biological Process	GO:0097553	calcium ion transmembrane import into cytosol	GRIN2C	IDA		Human	PMID:26875626
Biological Process	GO:0033058	directional locomotion	Grin2c	IGI	MGI:MGI:95820	Mouse	PMID:8987814
Biological Process	GO:0060079	excitatory postsynaptic potential	Grin2c	IMP	MGI:MGI:1928510	Mouse	PMID:8987814
Biological Process	GO:0060079	excitatory postsynaptic potential	Grin2c	IMP	MGI:MGI:1928301	Mouse	PMID:8756432
Biological Process	GO:0060079	excitatory postsynaptic potential	Grin2c	IGI	MGI:MGI:95820	Mouse	PMID:8987814
Biological Process	GO:0035235	ionotropic glutamate receptor signaling pathway	Grin2c	IDA		Rat	PMID:19793963\|RGD:150521643
Biological Process	GO:0042177	negative regulation of protein catabolic process	Grin2c	IGI	MGI:MGI:95820	Mouse	PMID:15317856
Biological Process	GO:0050885	neuromuscular process controlling balance	Grin2c	IMP	MGI:MGI:1928514	Mouse	PMID:9458051
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	Grin2c	IDA		Rat	PMID:19793963\|RGD:150521643
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	Grin2c	IDA		Rat	PMID:19793963\|RGD:150521643
Biological Process	GO:1903539	protein localization to postsynaptic membrane	Grin2c	IMP	MGI:MGI:3054830	Mouse	PMID:15317856
Biological Process	GO:1903539	protein localization to postsynaptic membrane	Grin2c	IGI	MGI:MGI:95820	Mouse	PMID:15317856
Biological Process	GO:0042391	regulation of membrane potential	Grin2c	IMP	MGI:MGI:1928301	Mouse	PMID:8756432
Biological Process	GO:1904062	regulation of monoatomic cation transmembrane transport	Grin2c	IDA		Rat	PMID:19793963\|RGD:150521643
Biological Process	GO:0009611	response to wounding	Grin2c	IGI	MGI:MGI:95820	Mouse	PMID:9512392

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.