Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GRIN3B
  • Mouse genes Grin3b
  • Rat genes Grin3b
  • Zfish genes grin3ba,grin3bb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Grin3b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005262	calcium channel activity	Grin3b	IMP		Mouse	MGI:MGI:3688366|PMID:14602821
Molecular Function	GO:0016594	glycine binding	Grin3b	IDA		Rat	PMID:11823786|RGD:632842
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GRIN3B	IDA		Human	PMID:22564863
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GRIN3B	IMP		Human	PMID:22564863
Molecular Function	GO:0005261	monoatomic cation channel activity	Grin3b	IDA		Rat	PMID:11823786|RGD:632842
Molecular Function	GO:0042165	neurotransmitter binding	Grin3b	IDA		Rat	PMID:11823786|RGD:632842
Molecular Function	GO:0030594	neurotransmitter receptor activity	Grin3b	IDA		Rat	PMID:11823786|RGD:632842
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Grin3b	IDA		Rat	PMID:23159309|RGD:13702288
Cellular Component	GO:0043025	neuronal cell body	Grin3b	IMP		Mouse	MGI:MGI:3688366|PMID:14602821
Cellular Component	GO:0043025	neuronal cell body	Grin3b	IDA		Mouse	MGI:MGI:2157765|PMID:11717388
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	Grin3b	IMP		Mouse	MGI:MGI:3688366|PMID:14602821
Cellular Component	GO:0017146	NMDA selective glutamate receptor complex	Grin3b	IDA		Rat	PMID:11823786|RGD:632842
Cellular Component	GO:0098839	postsynaptic density membrane	Grin3b	IDA		Rat	PMID:23159309|RGD:13702288
Cellular Component	GO:0048787	presynaptic active zone membrane	Grin3b	IDA		Rat	PMID:23159309|RGD:13702288
Biological Process	GO:0035235	ionotropic glutamate receptor signaling pathway	Grin3b	IDA		Rat	PMID:11823786|RGD:632842
Biological Process	GO:0051205	protein insertion into membrane	Grin3b	IMP		Mouse	MGI:MGI:3688366|PMID:14602821
Biological Process	GO:0051924	regulation of calcium ion transport	Grin3b	IMP		Mouse	MGI:MGI:3688366|PMID:14602821

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern