Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GRINA
  • Mouse genes Grina
  • Rat genes Grina
  • Zfish genes grinaa,grinab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Grina

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	GRINA	IPI	UniProtKB:Q01085-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GRINA	IPI	UniProtKB:Q01740	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GRINA	IPI	UniProtKB:Q3LI66	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GRINA	IPI	UniProtKB:Q3LI72	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GRINA	IPI	UniProtKB:Q6P531	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GRINA	IPI	UniProtKB:Q8TED1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GRINA	IPI	UniProtKB:Q9NWH2	Human	PMID:32296183
Molecular Function	GO:0044325	transmembrane transporter binding	Grina	IDA		Mouse	PMID:22240901
Cellular Component	GO:0005783	endoplasmic reticulum	Grina	IDA		Mouse	PMID:22240901
Cellular Component	GO:0005783	endoplasmic reticulum	grinaa	IDA		Zfish	PMID:31171717
Cellular Component	GO:0005794	Golgi apparatus	Grina	IDA		Mouse	PMID:22240901
Biological Process	GO:0032469	endoplasmic reticulum calcium ion homeostasis	Grina	IDA		Mouse	PMID:22240901
Biological Process	GO:0043066	negative regulation of apoptotic process	grinab	IDA		Zfish	PMID:22240901
Biological Process	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Grina	IGI	MGI:MGI:1341830	Mouse	PMID:22240901
Biological Process	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Grina	IGI	MGI:MGI:99682	Mouse	PMID:22240901
Biological Process	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Grina	IDA		Mouse	PMID:22240901
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	grinab	IMP	ZFIN:ZDB-MRPHLNO-120524-5	Zfish	PMID:22240901
Biological Process	GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	grinaa	IMP	ZFIN:ZDB-GENO-200521-17	Zfish	PMID:31171717

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern