Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GRIP2
  • Mouse genes Grip2
  • Rat genes Grip2
  • Zfish genes grip2a,grip2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Grip2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035254	glutamate receptor binding	Grip2	IDA		Rat	PMID:10436050|RGD:632957
Molecular Function	GO:0005515	protein binding	Grip2	IPI	PR:Q80T14	Mouse	PMID:14730302
Molecular Function	GO:0005515	protein binding	Grip2	IPI	RGD:621249	Rat	PMID:10896157|RGD:632892
Molecular Function	GO:0005515	protein binding	Grip2	IPI	UniProtKB:Q8VHY0	Rat	PMID:12458226|RGD:8553922
Molecular Function	GO:0005515	protein binding	Grip2	IPI	RGD:61911	Rat	PMID:18160640|RGD:4890437
Molecular Function	GO:0005515	protein binding	Grip2	IPI	UniProtKB:P19491	Rat	PMID:9697854|RGD:8553822
Molecular Function	GO:0005515	protein binding	Grip2	IPI	UniProtKB:P19491	Rat	PMID:9768844|RGD:632960
Molecular Function	GO:0005515	protein binding	Grip2	IPI	UniProtKB:P97879	Rat	PMID:9768844|RGD:632960
Cellular Component	GO:0005737	cytoplasm	Grip2	IDA		Rat	PMID:11978826|RGD:625696
Cellular Component	GO:0030425	dendrite	Grip2	IDA		Rat	PMID:9768844|RGD:632960
Cellular Component	GO:0043198	dendritic shaft	Grip2	IDA		Rat	PMID:10414981|RGD:632958
Cellular Component	GO:0098978	glutamatergic synapse	Grip2	IMP		Mouse	PMID:20956289
Cellular Component	GO:0098978	glutamatergic synapse	Grip2	IDA		Mouse	PMID:20956289
Cellular Component	GO:0098978	glutamatergic synapse	Grip2	IEP		Mouse	PMID:20956289
Cellular Component	GO:0098978	glutamatergic synapse	Grip2	IDA		Rat	PMID:9768844|RGD:632960
Cellular Component	GO:0016020	membrane	Grip2	IDA		Rat	PMID:10436050|RGD:632957
Cellular Component	GO:0044309	neuron spine	Grip2	IDA		Rat	PMID:11978826|RGD:625696
Cellular Component	GO:0044309	neuron spine	Grip2	IDA		Rat	PMID:20083202|RGD:4107359
Cellular Component	GO:0044309	neuron spine	Grip2	IMP		Rat	PMID:20083202|RGD:4107359
Cellular Component	GO:0043025	neuronal cell body	Grip2	IDA		Rat	PMID:11978826|RGD:625696
Cellular Component	GO:0005886	plasma membrane	Grip2	IDA		Rat	PMID:11978826|RGD:625696
Cellular Component	GO:0014069	postsynaptic density	Grip2	IDA		Rat	PMID:10436050|RGD:632957
Cellular Component	GO:0014069	postsynaptic density	Grip2	IDA		Rat	PMID:9768844|RGD:632960
Cellular Component	GO:0099092	postsynaptic density, intracellular component	Grip2	IDA		Rat	PMID:9768844|RGD:632960
Cellular Component	GO:0045211	postsynaptic membrane	Grip2	IDA		Rat	PMID:9768844|RGD:632960
Biological Process	GO:0014824	artery smooth muscle contraction	Grip2	IMP	MGI:MGI:3035933	Mouse	PMID:23117660
Biological Process	GO:0007010	cytoskeleton organization	grip2a	IMP	ZFIN:ZDB-GENO-160310-1	Zfish	PMID:24967891
Biological Process	GO:0007010	cytoskeleton organization	grip2a	IMP	ZFIN:ZDB-GENO-160310-2	Zfish	PMID:24967891
Biological Process	GO:0007010	cytoskeleton organization	grip2a	IMP	ZFIN:ZDB-GENO-100708-2	Zfish	PMID:24967891
Biological Process	GO:0033334	fin morphogenesis	grip2a	IMP	ZFIN:ZDB-MRPHLNO-100528-5	Zfish	PMID:20419147
Biological Process	GO:0008354	germ cell migration	grip2a	IMP	ZFIN:ZDB-GENO-160310-1	Zfish	PMID:24967891
Biological Process	GO:0008354	germ cell migration	grip2a	IMP	ZFIN:ZDB-GENO-100708-2	Zfish	PMID:24967891
Biological Process	GO:0008354	germ cell migration	grip2a	IMP	ZFIN:ZDB-GENO-160310-2	Zfish	PMID:24967891
Biological Process	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane	Grip2	IDA		Mouse	PMID:20956289
Biological Process	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane	Grip2	IEP		Mouse	PMID:20956289
Biological Process	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane	Grip2	IMP		Mouse	PMID:20956289
Biological Process	GO:0007219	Notch signaling pathway	Grip2	IDA		Mouse	PMID:23117660
Biological Process	GO:1904719	positive regulation of AMPA glutamate receptor clustering	Grip2	IMP		Rat	PMID:20083202|RGD:4107359
Biological Process	GO:0045777	positive regulation of blood pressure	Grip2	IMP	MGI:MGI:3035933	Mouse	PMID:23117660
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	Grip2	IMP		Rat	PMID:20083202|RGD:4107359
Biological Process	GO:0014042	positive regulation of neuron maturation	Grip2	IMP		Rat	PMID:20083202|RGD:4107359
Biological Process	GO:0015031	protein transport	Grip2	IMP		Rat	PMID:18160640|RGD:4890437
Biological Process	GO:0099003	vesicle-mediated transport in synapse	Grip2	IEP		Mouse	PMID:20956289
Biological Process	GO:0099003	vesicle-mediated transport in synapse	Grip2	IDA		Mouse	PMID:20956289
Biological Process	GO:0099003	vesicle-mediated transport in synapse	Grip2	IMP		Mouse	PMID:20956289

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern