Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GRM6
  • Mouse genes Grm6
  • Rat genes Grm6
  • Zfish genes grm6a,grm6b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Grm6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001640	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity	Grm6	IDA		Rat	PMID:8389366|RGD:69945
Molecular Function	GO:0008066	glutamate receptor activity	GRM6	IMP		Human	PMID:23452348
Molecular Function	GO:0005515	protein binding	GRM6	IPI	UniProtKB:O15303	Human	PMID:17405131
Molecular Function	GO:0042803	protein homodimerization activity	GRM6	IPI	UniProtKB:O15303	Human	PMID:17405131
Cellular Component	GO:0005789	endoplasmic reticulum membrane	GRM6	IDA		Human	PMID:17405131
Cellular Component	GO:0000139	Golgi membrane	GRM6	IDA		Human	PMID:17405131
Cellular Component	GO:0035841	new growing cell tip	Grm6	IDA		Mouse	PMID:19966281
Cellular Component	GO:0005886	plasma membrane	GRM6	IDA		Human	PMID:17405131
Biological Process	GO:0007196	adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway	Grm6	IDA		Rat	PMID:8389366|RGD:69945
Biological Process	GO:0007268	chemical synaptic transmission	Grm6	IEP		Rat	PMID:8389366|RGD:69945
Biological Process	GO:0050908	detection of light stimulus involved in visual perception	GRM6	IMP		Human	PMID:17405131
Biological Process	GO:0050908	detection of light stimulus involved in visual perception	grm6b	IMP	ZFIN:ZDB-MRPHLNO-120427-3	Zfish	PMID:22523578
Biological Process	GO:0007216	G protein-coupled glutamate receptor signaling pathway	GRM6	IMP		Human	PMID:23452348
Biological Process	GO:0007626	locomotory behavior	Grm6	IMP		Mouse	MGI:MGI:3641037|PMID:10842024
Biological Process	GO:1905665	positive regulation of calcium ion import across plasma membrane	GRM6	IMP		Human	PMID:23452348
Biological Process	GO:0060041	retina development in camera-type eye	Grm6	IMP	MGI:MGI:3605835	Mouse	PMID:21052544
Biological Process	GO:0050953	sensory perception of light stimulus	Grm6	IMP		Mouse	MGI:MGI:3641037|PMID:10842024
Biological Process	GO:0007165	signal transduction	Grm6	IGI	MGI:MGI:1330305	Mouse	PMID:19966281

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern