Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GSDMA
  • Mouse genes Gsdma3
  • Rat genes Gsdma
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gsdma3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1901612	cardiolipin binding	Gsdma3	IDA		Mouse	MGI:MGI:6467700|PMID:29695864
Molecular Function	GO:0005543	phospholipid binding	Gsdma3	IDA		Mouse	MGI:MGI:6467692|PMID:27281216
Molecular Function	GO:0005515	protein binding	GSDMA	IPI	UniProtKB:P02654	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GSDMA	IPI	UniProtKB:P55056	Human	PMID:32296183
Molecular Function	GO:0022829	wide pore channel activity	GSDMA	IDA		Human	PMID:35110732
Molecular Function	GO:0022829	wide pore channel activity	GSDMA	IDA		Human	PMID:35545676
Molecular Function	GO:0022829	wide pore channel activity	Gsdma3	IDA		Mouse	MGI:MGI:7327243|PMID:35545613
Molecular Function	GO:0022829	wide pore channel activity	Gsdma3	IDA		Mouse	MGI:MGI:6467692|PMID:27281216
Molecular Function	GO:0022829	wide pore channel activity	Gsdma3	IDA		Mouse	MGI:MGI:6867106|PMID:33883744
Molecular Function	GO:0022829	wide pore channel activity	Gsdma3	IDA		Mouse	MGI:MGI:6467700|PMID:29695864
Cellular Component	GO:0005829	cytosol	Gsdma3	IDA		Mouse	MGI:MGI:6467692|PMID:27281216
Cellular Component	GO:0016020	membrane	GSDMA	IDA		Human	PMID:35110732
Cellular Component	GO:0016020	membrane	GSDMA	IDA		Human	PMID:35545676
Cellular Component	GO:0016020	membrane	Gsdma3	IDA		Mouse	MGI:MGI:7327243|PMID:35545613
Cellular Component	GO:0016020	membrane	Gsdma3	IDA		Mouse	MGI:MGI:6467700|PMID:29695864
Cellular Component	GO:0005739	mitochondrion	Gsdma3	IDA		Mouse	MGI:MGI:6467689|PMID:26100518
Cellular Component	GO:0005634	nucleus	Gsdma3	IDA		Mouse	PMID:25860385
Cellular Component	GO:0048471	perinuclear region of cytoplasm	GSDMA	IDA		Human	PMID:17471240
Cellular Component	GO:0005886	plasma membrane	Gsdma3	IDA		Mouse	MGI:MGI:6467692|PMID:27281216
Biological Process	GO:0042640	anagen	Gsdma3	IMP	MGI:MGI:1861663	Mouse	PMID:17572385
Biological Process	GO:0036331	avascular cornea development in camera-type eye	Gsdma3	IMP	MGI:MGI:1856680	Mouse	PMID:9617549
Biological Process	GO:0042637	catagen	Gsdma3	IMP	MGI:MGI:4849547	Mouse	PMID:21805153
Biological Process	GO:0042637	catagen	Gsdma3	IMP	MGI:MGI:3526126	Mouse	PMID:15475261
Biological Process	GO:0042637	catagen	Gsdma3	IMP	MGI:MGI:2385837	Mouse	PMID:15737203
Biological Process	GO:0042742	defense response to bacterium	GSDMA	IDA		Human	PMID:35110732
Biological Process	GO:0042742	defense response to bacterium	GSDMA	IDA		Human	PMID:35545676
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	Gsdma3	IDA		Mouse	PMID:22585037
Biological Process	GO:0042633	hair cycle	Gsdma3	IMP	MGI:MGI:2385837	Mouse	PMID:12164921
Biological Process	GO:0001942	hair follicle development	Gsdma3	IMP		Mouse	MGI:MGI:6467719|PMID:28168650
Biological Process	GO:0001942	hair follicle development	Gsdma3	IMP	MGI:MGI:4849547	Mouse	PMID:20977888
Biological Process	GO:0001942	hair follicle development	Gsdma3	IMP	MGI:MGI:1861663	Mouse	PMID:9434940
Biological Process	GO:0001942	hair follicle development	Gsdma3	IMP	MGI:MGI:2385837	Mouse	PMID:15737203
Biological Process	GO:0031069	hair follicle morphogenesis	Gsdma3	IMP	MGI:MGI:3526126	Mouse	PMID:15475261
Biological Process	GO:0030879	mammary gland development	Gsdma3	IMP		Mouse	MGI:MGI:6467719|PMID:28168650
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	Gsdma3	IDA		Mouse	PMID:25860385
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	Gsdma3	IMP	MGI:MGI:4849547	Mouse	PMID:25860385
Biological Process	GO:0051886	negative regulation of timing of anagen	Gsdma3	IDA		Mouse	PMID:25860385
Biological Process	GO:0043065	positive regulation of apoptotic process	Gsdma3	IMP	MGI:MGI:4849547	Mouse	PMID:21805153
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	Gsdma3	IDA		Mouse	PMID:22585037
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	Gsdma3	IDA		Mouse	MGI:MGI:6867106|PMID:33883744
Biological Process	GO:0012501	programmed cell death	Gsdma3	IMP		Mouse	MGI:MGI:6467689|PMID:26100518
Biological Process	GO:0012501	programmed cell death	Gsdma3	IMP		Mouse	MGI:MGI:6467718|PMID:25825937
Biological Process	GO:0051259	protein complex oligomerization	Gsdma3	IDA		Mouse	MGI:MGI:6467700|PMID:29695864
Biological Process	GO:0051259	protein complex oligomerization	Gsdma3	IDA		Mouse	MGI:MGI:6467692|PMID:27281216
Biological Process	GO:0051259	protein complex oligomerization	Gsdma3	IDA		Mouse	MGI:MGI:7327243|PMID:35545613
Biological Process	GO:0070269	pyroptosis	GSDMA	IDA		Human	PMID:35110732
Biological Process	GO:0070269	pyroptosis	GSDMA	IDA		Human	PMID:35545676
Biological Process	GO:0070269	pyroptosis	Gsdma3	IDA		Mouse	MGI:MGI:7327243|PMID:35545613
Biological Process	GO:0070269	pyroptosis	Gsdma3	IDA		Mouse	MGI:MGI:6467692|PMID:27281216
Biological Process	GO:0070269	pyroptosis	Gsdma3	IDA		Mouse	MGI:MGI:6467700|PMID:29695864
Biological Process	GO:0001949	sebaceous gland cell differentiation	Gsdma3	IMP	MGI:MGI:2385837	Mouse	PMID:15737203
Biological Process	GO:0043588	skin development	Gsdma3	IMP	MGI:MGI:1856680	Mouse	PMID:9617549
Biological Process	GO:0043588	skin development	Gsdma3	IMP	MGI:MGI:1861663	Mouse	PMID:9434940
Biological Process	GO:0035019	somatic stem cell population maintenance	Gsdma3	IMP	MGI:MGI:4849547	Mouse	PMID:22155111

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern