Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GSS
  • Mouse genes Gss
  • Rat genes Gss
  • Zfish genes gss
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gss

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	GSS	IDA		Human	PMID:10369661
Molecular Function	GO:0005524	ATP binding	Gss	IDA		Rat	PMID:10964706|RGD:1599340
Molecular Function	GO:0043295	glutathione binding	GSS	IDA		Human	PMID:10369661
Molecular Function	GO:0043295	glutathione binding	Gss	IDA		Rat	PMID:10964706|RGD:1599340
Molecular Function	GO:0004363	glutathione synthase activity	Gss	IDA		Mouse	PMID:8660701
Molecular Function	GO:0004363	glutathione synthase activity	Gss	IDA		Rat	PMID:10964706|RGD:1599340
Molecular Function	GO:0004363	glutathione synthase activity	Gss	IDA		Rat	PMID:7862666|RGD:69853
Molecular Function	GO:0016594	glycine binding	Gss	IDA		Rat	PMID:10964706|RGD:1599340
Molecular Function	GO:0042802	identical protein binding	GSS	IPI	UniProtKB:P48637	Human	PMID:21988832
Molecular Function	GO:0042802	identical protein binding	GSS	IPI	UniProtKB:P48637	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	GSS	IPI	UniProtKB:P48637	Human	PMID:26871637
Molecular Function	GO:0042802	identical protein binding	GSS	IPI	UniProtKB:P48637	Human	PMID:32296183
Molecular Function	GO:0042802	identical protein binding	Gss	IPI	RGD:2752	Rat	PMID:7862666|RGD:69853
Molecular Function	GO:0000287	magnesium ion binding	GSS	IDA		Human	PMID:10369661
Molecular Function	GO:0042277	peptide binding	Gss	IPI	CHEBI:17515	Rat	PMID:10964706|RGD:1599340
Molecular Function	GO:0042277	peptide binding	Gss	IPI	PubChem_Compound:193514	Rat	PMID:10964706|RGD:1599340
Molecular Function	GO:0005515	protein binding	GSS	IPI	UniProtKB:P54274	Human	PMID:21044950
Molecular Function	GO:0042803	protein homodimerization activity	GSS	IDA		Human	PMID:10369661
Cellular Component	GO:0005829	cytosol	Gss	IDA		Rat	PMID:12044560|RGD:11353818
Cellular Component	GO:0070062	extracellular exosome	GSS	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	GSS	HDA		Human	PMID:23533145
Biological Process	GO:0007568	aging	Gss	IEP		Rat	PMID:18653662|RGD:2301454
Biological Process	GO:0006750	glutathione biosynthetic process	Gss	IDA		Mouse	MGI:MGI:81780|PMID:8660701
Biological Process	GO:0006750	glutathione biosynthetic process	Gss	IDA		Rat	PMID:10964706|RGD:1599340
Biological Process	GO:0043200	response to amino acid	Gss	IEP		Rat	PMID:19212806|RGD:2307430
Biological Process	GO:0046686	response to cadmium ion	Gss	IDA		Mouse	PMID:8660701
Biological Process	GO:0031667	response to nutrient levels	Gss	IEP		Rat	PMID:19212806|RGD:2307430
Biological Process	GO:0034612	response to tumor necrosis factor	Gss	IEP		Rat	PMID:16011481|RGD:2316556
Biological Process	GO:0009410	response to xenobiotic stimulus	Gss	IEP		Rat	PMID:18653662|RGD:2301454

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern