Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GSTM1,GSTM5
  • Mouse genes Gstm1
  • Rat genes Gstm1
  • Zfish genes gstm.1,gstm.2,gstm.3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gstm1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	GSTM1	IPI	UniProtKB:P09488	Human	PMID:8373352
Molecular Function	GO:0043295	glutathione binding	GSTM1	IDA		Human	PMID:8373352
Molecular Function	GO:0043295	glutathione binding	Gstm1	IDA		Rat	PMID:17112229|RGD:12793043
Molecular Function	GO:0004364	glutathione transferase activity	GSTM1	IDA		Human	PMID:8373352
Molecular Function	GO:0004364	glutathione transferase activity	GSTM1	IDA		Human	PMID:9084911
Molecular Function	GO:0004364	glutathione transferase activity	GSTM5	IDA		Human	PMID:10587441
Molecular Function	GO:0004364	glutathione transferase activity	Gstm1	IDA		Rat	PMID:10229687|RGD:70307
Molecular Function	GO:0004364	glutathione transferase activity	Gstm1	IDA		Rat	PMID:17112229|RGD:12793043
Molecular Function	GO:0004364	glutathione transferase activity	gstm.1	IDA		Zfish	PMID:25461745
Molecular Function	GO:0004364	glutathione transferase activity	gstm.3	IDA		Zfish	PMID:25461745
Molecular Function	GO:0042802	identical protein binding	GSTM5	IPI	UniProtKB:P46439	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	GSTM5	IPI	UniProtKB:P46439	Human	PMID:32296183
Molecular Function	GO:0042802	identical protein binding	Gstm1	IPI	PR:P10649	Mouse	PMID:2689439
Molecular Function	GO:0042802	identical protein binding	Gstm1	IPI	RGD:2755	Rat	PMID:11015213|RGD:2293821
Molecular Function	GO:0016151	nickel cation binding	Gstm1	IDA		Rat	PMID:7831282|RGD:7771537
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:Q6FGJ9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:Q9Y2J4-4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:P21266	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:P28161	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:P21266	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:Q9Y2J4	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:P21266	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:P28161	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:Q03013	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:Q92917	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:Q9Y2J4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Gstm1	IPI	PR:P15626	Mouse	PMID:2689439
Molecular Function	GO:0005515	protein binding	Gstm1	IPI	PR:Q8CDK3	Mouse	PMID:19706271
Molecular Function	GO:0042803	protein homodimerization activity	GSTM1	IPI	UniProtKB:P09488	Human	PMID:8373352
Molecular Function	GO:0019901	protein kinase binding	Gstm1	IPI	RGD:620905	Rat	PMID:23741294|RGD:10401936
Molecular Function	GO:0005496	steroid binding	Gstm1	IPI	PubChem_Substance:4594	Rat	PMID:10229687|RGD:70307
Molecular Function	GO:0005496	steroid binding	Gstm1	IPI	PubChem_Substance:5757	Rat	PMID:10229687|RGD:70307
Cellular Component	GO:0005737	cytoplasm	GSTM1	IDA		Human	PMID:8373352
Cellular Component	GO:0005829	cytosol	GSTM1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	GSTM5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Gstm1	IDA		Rat	PMID:17112229|RGD:12793043
Cellular Component	GO:0005576	extracellular region	Gstm1	IDA		Rat	PMID:10229687|RGD:70307
Cellular Component	GO:0045171	intercellular bridge	GSTM1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045171	intercellular bridge	GSTM5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043209	myelin sheath	Gstm1	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0032991	protein-containing complex	Gstm1	IDA		Rat	PMID:11015213|RGD:2293821
Biological Process	GO:0007568	aging	Gstm1	IEP		Rat	PMID:30444463|RGD:14701004
Biological Process	GO:0070458	cellular detoxification of nitrogen compound	GSTM1	IDA		Human	PMID:8373352
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Gstm1	IDA		Mouse	PMID:8512323
Biological Process	GO:1901687	glutathione derivative biosynthetic process	GSTM1	IDA		Human	PMID:9084911
Biological Process	GO:0006749	glutathione metabolic process	GSTM1	IDA		Human	PMID:8373352
Biological Process	GO:0006749	glutathione metabolic process	GSTM5	IDA		Human	PMID:10587441
Biological Process	GO:0006749	glutathione metabolic process	Gstm1	IDA		Rat	PMID:10229687|RGD:70307
Biological Process	GO:0006749	glutathione metabolic process	Gstm1	IMP		Rat	PMID:12027896|RGD:2302181
Biological Process	GO:0051122	hepoxilin biosynthetic process	GSTM1	IDA		Human	PMID:21046276
Biological Process	GO:0018916	nitrobenzene metabolic process	GSTM1	IDA		Human	PMID:8373352
Biological Process	GO:0006693	prostaglandin metabolic process	GSTM1	IDA		Human	PMID:9084911
Biological Process	GO:0043200	response to amino acid	Gstm1	IEP		Rat	PMID:11040448|RGD:2293820
Biological Process	GO:0046677	response to antibiotic	Gstm1	IEP		Rat	PMID:8773182|RGD:2293822
Biological Process	GO:0048678	response to axon injury	Gstm1	IEP		Rat	PMID:20298122|RGD:7771530
Biological Process	GO:0045471	response to ethanol	Gstm1	IEP		Rat	PMID:22545783|RGD:7495839
Biological Process	GO:0010288	response to lead ion	Gstm1	IEP		Rat	PMID:9750042|RGD:7495837
Biological Process	GO:0010226	response to lithium ion	Gstm1	IEP		Rat	PMID:18082333|RGD:2293846
Biological Process	GO:0010038	response to metal ion	Gstm1	IEP		Rat	PMID:23470461|RGD:7495836
Biological Process	GO:0009410	response to xenobiotic stimulus	Gstm1	IEP		Rat	PMID:18754104|RGD:2303374
Biological Process	GO:0042178	xenobiotic catabolic process	GSTM1	IDA		Human	PMID:8373352
Biological Process	GO:0042178	xenobiotic catabolic process	Gstm1	IDA		Rat	PMID:17112229|RGD:12793043

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern