Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GSTM1,GSTM5
  • Mouse genes Gstm2
  • Rat genes Gstm2
  • Zfish genes gstm.1,gstm.2,gstm.3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gstm2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	GSTM1	IPI	UniProtKB:P09488	Human	PMID:8373352
Molecular Function	GO:0043295	glutathione binding	GSTM1	IDA		Human	PMID:8373352
Molecular Function	GO:0043295	glutathione binding	Gstm2	IDA		Rat	PMID:17112229|RGD:12793043
Molecular Function	GO:0004364	glutathione transferase activity	GSTM1	IDA		Human	PMID:8373352
Molecular Function	GO:0004364	glutathione transferase activity	GSTM1	IDA		Human	PMID:9084911
Molecular Function	GO:0004364	glutathione transferase activity	GSTM5	IDA		Human	PMID:10587441
Molecular Function	GO:0004364	glutathione transferase activity	Gstm2	IDA		Mouse	PMID:8442656
Molecular Function	GO:0004364	glutathione transferase activity	Gstm2	IDA		Rat	PMID:17112229|RGD:12793043
Molecular Function	GO:0004364	glutathione transferase activity	gstm.1	IDA		Zfish	PMID:25461745
Molecular Function	GO:0004364	glutathione transferase activity	gstm.3	IDA		Zfish	PMID:25461745
Molecular Function	GO:0042802	identical protein binding	GSTM5	IPI	UniProtKB:P46439	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	GSTM5	IPI	UniProtKB:P46439	Human	PMID:32296183
Molecular Function	GO:0042802	identical protein binding	Gstm2	IPI	PR:P15626	Mouse	PMID:2689439
Molecular Function	GO:0042802	identical protein binding	Gstm2	IPI	RGD:2756	Rat	PMID:11015213|RGD:2293821
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:Q6FGJ9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:Q9Y2J4-4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:P21266	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:P28161	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:P21266	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:Q9Y2J4	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:P21266	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:P28161	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:Q03013	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:Q92917	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GSTM5	IPI	UniProtKB:Q9Y2J4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Gstm2	IPI	PR:P10649	Mouse	PMID:2689439
Molecular Function	GO:0042803	protein homodimerization activity	GSTM1	IPI	UniProtKB:P09488	Human	PMID:8373352
Cellular Component	GO:0005737	cytoplasm	GSTM1	IDA		Human	PMID:8373352
Cellular Component	GO:0005829	cytosol	GSTM1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	GSTM5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Gstm2	IDA		Rat	PMID:17112229|RGD:12793043
Cellular Component	GO:0005829	cytosol	Gstm2	IDA		Rat	PMID:8968379|RGD:7242738
Cellular Component	GO:0045171	intercellular bridge	GSTM1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045171	intercellular bridge	GSTM5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Gstm2	IDA		Rat	PMID:11684093|RGD:2302183
Cellular Component	GO:0032991	protein-containing complex	Gstm2	IDA		Rat	PMID:11015213|RGD:2293821
Biological Process	GO:0007568	aging	Gstm2	IEP		Rat	PMID:16029322|RGD:2302179
Biological Process	GO:0070458	cellular detoxification of nitrogen compound	GSTM1	IDA		Human	PMID:8373352
Biological Process	GO:1901687	glutathione derivative biosynthetic process	GSTM1	IDA		Human	PMID:9084911
Biological Process	GO:0006749	glutathione metabolic process	GSTM1	IDA		Human	PMID:8373352
Biological Process	GO:0006749	glutathione metabolic process	GSTM5	IDA		Human	PMID:10587441
Biological Process	GO:0006749	glutathione metabolic process	Gstm2	IMP		Rat	PMID:12027896|RGD:2302181
Biological Process	GO:0051122	hepoxilin biosynthetic process	GSTM1	IDA		Human	PMID:21046276
Biological Process	GO:0018916	nitrobenzene metabolic process	GSTM1	IDA		Human	PMID:8373352
Biological Process	GO:0006693	prostaglandin metabolic process	GSTM1	IDA		Human	PMID:9084911
Biological Process	GO:1902168	response to catechin	Gstm2	IEP		Rat	PMID:10927022|RGD:2302182
Biological Process	GO:0033595	response to genistein	Gstm2	IEP		Rat	PMID:19451092|RGD:7495843
Biological Process	GO:0010038	response to metal ion	Gstm2	IEP		Rat	PMID:23470461|RGD:7495836
Biological Process	GO:0014070	response to organic cyclic compound	Gstm2	IEP		Rat	PMID:14646352|RGD:2302180
Biological Process	GO:0042178	xenobiotic catabolic process	GSTM1	IDA		Human	PMID:8373352
Biological Process	GO:0042178	xenobiotic catabolic process	Gstm2	IDA		Rat	PMID:17112229|RGD:12793043

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern