Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GSTM4
  • Mouse genes Gstm4
  • Rat genes Gstm4
  • Zfish genes gstm.1,gstm.2,gstm.3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gstm4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	GSTM4	IPI	UniProtKB:Q03013	Human	PMID:8373352
Molecular Function	GO:0043295	glutathione binding	GSTM4	IDA		Human	PMID:8373352
Molecular Function	GO:0004364	glutathione transferase activity	GSTM4	IDA		Human	PMID:8203914
Molecular Function	GO:0004364	glutathione transferase activity	GSTM4	IDA		Human	PMID:8373352
Molecular Function	GO:0004364	glutathione transferase activity	Gstm4	IDA		Mouse	PMID:12069689
Molecular Function	GO:0004364	glutathione transferase activity	gstm.1	IDA		Zfish	PMID:25461745
Molecular Function	GO:0004364	glutathione transferase activity	gstm.3	IDA		Zfish	PMID:25461745
Molecular Function	GO:0004464	leukotriene-C4 synthase activity	GSTM4	IDA		Human	PMID:27791009
Molecular Function	GO:0005515	protein binding	GSTM4	IPI	UniProtKB:Q6FGJ9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GSTM4	IPI	UniProtKB:P21266	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	GSTM4	IPI	UniProtKB:P21266	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GSTM4	IPI	UniProtKB:P46439	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GSTM4	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0042803	protein homodimerization activity	GSTM4	IPI	UniProtKB:Q03013	Human	PMID:8373352
Cellular Component	GO:0005737	cytoplasm	GSTM4	IDA		Human	PMID:8373352
Cellular Component	GO:0005829	cytosol	GSTM4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045171	intercellular bridge	GSTM4	IDA		Human	GO_REF:0000052
Biological Process	GO:0006749	glutathione metabolic process	GSTM4	IDA		Human	PMID:8373352
Biological Process	GO:0042759	long-chain fatty acid biosynthetic process	GSTM4	IDA		Human	PMID:27791009
Biological Process	GO:0018916	nitrobenzene metabolic process	Gstm4	IDA		Mouse	PMID:12069689
Biological Process	GO:0042178	xenobiotic catabolic process	GSTM4	IDA		Human	PMID:8373352
Biological Process	GO:0042178	xenobiotic catabolic process	Gstm4	IDA		Mouse	PMID:12069689

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern