Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GSTO1
  • Mouse genes Gsto1
  • Rat genes Gsto1
  • Zfish genes gsto1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gsto1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045174	glutathione dehydrogenase (ascorbate) activity	GSTO1	IDA		Human	PMID:11511179
Molecular Function	GO:0045174	glutathione dehydrogenase (ascorbate) activity	Gsto1	IDA		Rat	PMID:9786866|RGD:70644
Molecular Function	GO:0004364	glutathione transferase activity	GSTO1	IDA		Human	PMID:11511179
Molecular Function	GO:0016491	oxidoreductase activity	GSTO1	IDA		Human	PMID:11511179
Molecular Function	GO:0005515	protein binding	GSTO1	IPI	UniProtKB:P04792	Human	PMID:25277244
Cellular Component	GO:0030424	axon	Gsto1	IDA		Rat	PMID:11311527|RGD:5490519
Cellular Component	GO:0005604	basement membrane	Gsto1	IDA		Rat	PMID:11311527|RGD:5490519
Cellular Component	GO:0044297	cell body	Gsto1	IDA		Rat	PMID:11311527|RGD:5490519
Cellular Component	GO:0005737	cytoplasm	GSTO1	IDA		Human	PMID:11511179
Cellular Component	GO:0005737	cytoplasm	Gsto1	IDA		Rat	PMID:11311527|RGD:5490519
Cellular Component	GO:0005829	cytosol	Gsto1	IDA		Rat	PMID:9786866|RGD:70644
Cellular Component	GO:0070062	extracellular exosome	GSTO1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	GSTO1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	GSTO1	HDA		Human	PMID:23533145
Cellular Component	GO:0043209	myelin sheath	Gsto1	IDA		Rat	PMID:11311527|RGD:5490519
Cellular Component	GO:0031965	nuclear membrane	Gsto1	IDA		Rat	PMID:11311527|RGD:5490519
Biological Process	GO:0071243	cellular response to arsenic-containing substance	GSTO1	IDA		Human	PMID:11511179
Biological Process	GO:0019853	L-ascorbic acid biosynthetic process	Gsto1	IMP		Rat	PMID:9786866|RGD:70644
Biological Process	GO:0019852	L-ascorbic acid metabolic process	GSTO1	IDA		Human	PMID:11511179
Biological Process	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	GSTO1	IDA		Human	PMID:11035031
Biological Process	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity	GSTO1	IDA		Human	PMID:11035031
Biological Process	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	GSTO1	IDA		Human	PMID:11035031
Biological Process	GO:0042178	xenobiotic catabolic process	GSTO1	IDA		Human	PMID:12928150

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern