Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GTF2A1
  • Mouse genes Gtf2a1
  • Rat genes Gtf2a1
  • Zfish genes gtf2a1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gtf2a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	GTF2A1	IDA		Human	PMID:7724559
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:P62380	Human	PMID:24835508
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:P23511	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:P52657	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:P20226	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:P52657	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:P62380	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:P52657	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:P23511-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:P52657	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:P62333	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:P62380	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:P86480	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:Q02446	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:Q96CA5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:D3DTS7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:O75460-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:P01112	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:Q0VDC6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:P20226	Human	PMID:8006019
Molecular Function	GO:0005515	protein binding	GTF2A1	IPI	UniProtKB:P52657	Human	PMID:8626665
Molecular Function	GO:0005515	protein binding	Gtf2a1	IPI	PR:Q8R4I4	Mouse	PMID:15927180
Molecular Function	GO:0005515	protein binding	Gtf2a1	IPI	MGI:MGI:1339946	Mouse	PMID:15927180
Molecular Function	GO:0046982	protein heterodimerization activity	GTF2A1	IPI	UniProtKB:P52657	Human	PMID:8626665
Molecular Function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	GTF2A1	IDA		Human	PMID:29111974
Molecular Function	GO:0016251	RNA polymerase II general transcription initiation factor activity	GTF2A1	IDA		Human	PMID:27193682
Molecular Function	GO:0001091	RNA polymerase II general transcription initiation factor binding	GTF2A1	IPI	UniProtKB:P52657	Human	PMID:8626665
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Gtf2a1	IPI	PR:Q8BIA3	Mouse	PMID:19235719
Molecular Function	GO:0017025	TBP-class protein binding	GTF2A1	IPI	UniProtKB:P20226	Human	PMID:29111974
Molecular Function	GO:0017025	TBP-class protein binding	GTF2A1	IPI	UniProtKB:P20226	Human	PMID:7724559
Cellular Component	GO:0005737	cytoplasm	Gtf2a1	IDA		Mouse	PMID:15927180
Cellular Component	GO:0005829	cytosol	GTF2A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	GTF2A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	GTF2A1	IDA		Human	PMID:10022900
Cellular Component	GO:0005634	nucleus	Gtf2a1	IDA		Mouse	PMID:15927180
Cellular Component	GO:0005672	transcription factor TFIIA complex	GTF2A1	IPI		Human	PMID:8626665
Cellular Component	GO:0005672	transcription factor TFIIA complex	GTF2A1	IDA		Human	PMID:7724559
Cellular Component	GO:0005672	transcription factor TFIIA complex	Gtf2a1	IDA		Mouse	PMID:15927180
Cellular Component	GO:0005669	transcription factor TFIID complex	GTF2A1	IDA		Human	PMID:27193682
Cellular Component	GO:0097550	transcription preinitiation complex	GTF2A1	IDA		Human	PMID:8224850
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	GTF2A1	IDA		Human	PMID:10022900
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	GTF2A1	IDA		Human	PMID:11030333
Biological Process	GO:0006366	transcription by RNA polymerase II	GTF2A1	IDA		Human	PMID:27193682
Biological Process	GO:0006366	transcription by RNA polymerase II	GTF2A1	IDA		Human	PMID:7724559
Biological Process	GO:0006366	transcription by RNA polymerase II	GTF2A1	IDA		Human	PMID:7958900

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern