Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GTF2H2,GTF2H2C,GTF2H2C_2
  • Mouse genes Gtf2h2
  • Rat genes Gtf2h2
  • Zfish genes gtf2h2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gtf2h2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	GTF2H2	IPI	UniProtKB:P18074	Human	PMID:11445587
Molecular Function	GO:0005515	protein binding	GTF2H2	IPI	UniProtKB:Q6ZYL4	Human	PMID:16669699
Molecular Function	GO:0005515	protein binding	GTF2H2	IPI	UniProtKB:P61201	Human	PMID:17438371
Molecular Function	GO:0005515	protein binding	GTF2H2	IPI	UniProtKB:Q6ZYL4	Human	PMID:19172752
Molecular Function	GO:0005515	protein binding	GTF2H2	IPI	UniProtKB:P18074	Human	PMID:19934020
Molecular Function	GO:0005515	protein binding	GTF2H2	IPI	UniProtKB:P32780	Human	PMID:19934020
Molecular Function	GO:0005515	protein binding	GTF2H2	IPI	UniProtKB:P32780	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	GTF2H2	IPI	UniProtKB:Q6ZYL4	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	GTF2H2	IPI	UniProtKB:P18074	Human	PMID:27193682
Molecular Function	GO:0005515	protein binding	GTF2H2	IPI	UniProtKB:Q6ZYL4	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	GTF2H2	IPI	UniProtKB:Q13216-1	Human	PMID:7664335
Molecular Function	GO:0005515	protein binding	GTF2H2	IPI	UniProtKB:P18074	Human	PMID:8652557
Molecular Function	GO:0005515	protein binding	GTF2H2	IPI	UniProtKB:P19447	Human	PMID:8652557
Molecular Function	GO:0005515	protein binding	GTF2H2	IPI	UniProtKB:P28715	Human	PMID:8652557
Molecular Function	GO:0005515	protein binding	GTF2H2	IPI	UniProtKB:Q13889	Human	PMID:8652557
Molecular Function	GO:0005515	protein binding	GTF2H2	IPI	UniProtKB:P51948	Human	PMID:8692842
Molecular Function	GO:0005515	protein binding	GTF2H2C	IPI	UniProtKB:Q13889	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	GTF2H2C	IPI	UniProtKB:P18074	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GTF2H2C	IPI	UniProtKB:Q13889	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GTF2H2C	IPI	UniProtKB:Q86Y13	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GTF2H2C	IPI	UniProtKB:Q13889	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	GTF2H2C	IPI	UniProtKB:O00482-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GTF2H2C	IPI	UniProtKB:Q8N2R8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GTF2H2C	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0016251	RNA polymerase II general transcription initiation factor activity	GTF2H2	IDA		Human	PMID:10924514
Molecular Function	GO:0016251	RNA polymerase II general transcription initiation factor activity	GTF2H2	IDA		Human	PMID:27193682
Cellular Component	GO:0000438	core TFIIH complex portion of holo TFIIH complex	GTF2H2	IDA		Human	PMID:27193682
Cellular Component	GO:0016607	nuclear speck	GTF2H2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	GTF2H2C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	GTF2H2	IDA		Human	PMID:27193682
Cellular Component	GO:0005669	transcription factor TFIID complex	GTF2H2	IDA		Human	PMID:27193682
Cellular Component	GO:0000439	transcription factor TFIIH core complex	GTF2H2	IDA		Human	PMID:11445587
Cellular Component	GO:0005675	transcription factor TFIIH holo complex	GTF2H2	IDA		Human	PMID:9852112
Biological Process	GO:0002031	G protein-coupled receptor internalization	GTF2H2	IMP		Human	PMID:15775968
Biological Process	GO:1905776	positive regulation of DNA helicase activity	GTF2H2	IDA		Human	PMID:11445587
Biological Process	GO:0006366	transcription by RNA polymerase II	GTF2H2	IDA		Human	PMID:27193682
Biological Process	GO:0006366	transcription by RNA polymerase II	GTF2H2	IDA		Human	PMID:9852112
Biological Process	GO:0006367	transcription initiation at RNA polymerase II promoter	GTF2H2	IDA		Human	PMID:10924514

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern