Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GTF2I
  • Mouse genes Gtf2i
  • Rat genes Gtf2i
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gtf2i

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	GTF2I	IDA		Human	PMID:9334314
Molecular Function	GO:0005515	protein binding	GTF2I	IPI	UniProtKB:Q06187	Human	PMID:19214191
Molecular Function	GO:0005515	protein binding	GTF2I	IPI	UniProtKB:P38398	Human	PMID:21407215
Molecular Function	GO:0005515	protein binding	GTF2I	IPI	UniProtKB:Q06187	Human	PMID:9012831
Molecular Function	GO:0005515	protein binding	Gtf2i	IPI	PR:Q99NI3	Mouse	PMID:22899722
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	GTF2I	IPI	UniProtKB:P54821	Human	PMID:9334314
Cellular Component	GO:0016020	membrane	GTF2I	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	GTF2I	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	GTF2I	IDA		Human	PMID:19242469
Cellular Component	GO:0005634	nucleus	Gtf2i	IDA		Mouse	PMID:22899722
Biological Process	GO:0009790	embryo development	Gtf2i	IMP	MGI:MGI:3831527	Mouse	PMID:19109438
Biological Process	GO:0016525	negative regulation of angiogenesis	GTF2I	IDA		Human	PMID:19242469
Biological Process	GO:0051481	negative regulation of cytosolic calcium ion concentration	Gtf2i	IMP		Rat	PMID:17023658|RGD:2306422
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	GTF2I	IDA		Human	PMID:9334314

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern