Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GUSB
  • Mouse genes Gusb
  • Rat genes Gusb
  • Zfish genes gusb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gusb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004566	beta-glucuronidase activity	Gusb	IMP		Mouse	PMID:20385825
Molecular Function	GO:0004566	beta-glucuronidase activity	Gusb	IDA		Mouse	PMID:8200966
Molecular Function	GO:0004566	beta-glucuronidase activity	Gusb	IMP	MGI:MGI:1856041	Mouse	PMID:11273777
Molecular Function	GO:0004566	beta-glucuronidase activity	Gusb	IMP	MGI:MGI:2152564	Mouse	PMID:9774663
Molecular Function	GO:0004566	beta-glucuronidase activity	Gusb	IDA		Mouse	PMID:4777306
Molecular Function	GO:0004566	beta-glucuronidase activity	Gusb	IDA		Mouse	PMID:4841576
Molecular Function	GO:0004566	beta-glucuronidase activity	Gusb	IDA		Mouse	PMID:1914521
Molecular Function	GO:0004566	beta-glucuronidase activity	Gusb	IDA		Mouse	PMID:19751987
Molecular Function	GO:0004566	beta-glucuronidase activity	Gusb	IDA		Mouse	PMID:7203014
Molecular Function	GO:0004566	beta-glucuronidase activity	Gusb	IDA		Rat	PMID:3355537|RGD:728562
Molecular Function	GO:0004566	beta-glucuronidase activity	Gusb	IDA		Rat	PMID:8702598|RGD:1625498
Molecular Function	GO:0004566	beta-glucuronidase activity	Gusb	IMP		Rat	PMID:8717430|RGD:1625507
Molecular Function	GO:0030246	carbohydrate binding	Gusb	IDA		Rat	PMID:8702598|RGD:1625498
Molecular Function	GO:0016787	hydrolase activity	Gusb	IDA		Mouse	PMID:19710420
Molecular Function	GO:0019904	protein domain specific binding	GUSB	IPI	UniProtKB:P08169	Human	PMID:20028034
Molecular Function	GO:0005102	signaling receptor binding	GUSB	IPI	UniProtKB:P08169	Human	PMID:20028034
Cellular Component	GO:0070062	extracellular exosome	GUSB	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	GUSB	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	GUSB	IDA		Human	PMID:25645918
Cellular Component	GO:0005615	extracellular space	Gusb	IDA		Mouse	PMID:19710420
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	GUSB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043202	lysosomal lumen	Gusb	IDA		Mouse	PMID:8200966
Cellular Component	GO:0043202	lysosomal lumen	Gusb	IMP	MGI:MGI:1856041	Mouse	PMID:23897660
Cellular Component	GO:0005764	lysosome	Gusb	IDA		Mouse	PMID:4841576
Cellular Component	GO:0005764	lysosome	Gusb	IDA		Mouse	PMID:9774663
Cellular Component	GO:0005764	lysosome	Gusb	IDA		Mouse	PMID:29514215
Cellular Component	GO:0005764	lysosome	Gusb	IDA		Rat	PMID:8702598|RGD:1625498
Cellular Component	GO:0016020	membrane	GUSB	HDA		Human	PMID:19946888
Biological Process	GO:0005975	carbohydrate metabolic process	Gusb	IDA		Mouse	PMID:4841576
Biological Process	GO:0030207	chondroitin sulfate catabolic process	Gusb	IMP	MGI:MGI:1856041	Mouse	PMID:23897660
Biological Process	GO:0019391	glucuronoside catabolic process	Gusb	IDA		Mouse	PMID:19751987
Biological Process	GO:0030200	heparan sulfate proteoglycan catabolic process	Gusb	IMP	MGI:MGI:1856041	Mouse	PMID:11273777
Biological Process	GO:0030200	heparan sulfate proteoglycan catabolic process	Gusb	IMP	MGI:MGI:1856041	Mouse	PMID:23897660
Biological Process	GO:0030214	hyaluronan catabolic process	Gusb	IMP		Mouse	PMID:20385825

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern