Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes H1-0
  • Mouse genes H1f0
  • Rat genes H1f0
  • Zfish genes h1-0
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set H1f0

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031490	chromatin DNA binding	H1-0	IDA		Human	PMID:15911621
Molecular Function	GO:0003677	DNA binding	H1f0	EXP		Mouse	MGI:MGI:7310011|PMID:11584004
Molecular Function	GO:0003690	double-stranded DNA binding	H1f0	IMP		Mouse	MGI:MGI:5882893|PMID:16006555
Molecular Function	GO:0003680	minor groove of adenine-thymine-rich DNA binding	H1f0	IMP		Mouse	MGI:MGI:5882916|PMID:11413144
Molecular Function	GO:0005515	protein binding	H1-0	IPI	UniProtKB:Q8IYW5	Human	PMID:26503038
Molecular Function	GO:0005515	protein binding	H1-0	IPI	UniProtKB:P04014	Human	PMID:9499053
Molecular Function	GO:0003723	RNA binding	H1-0	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	H1-0	HDA		Human	PMID:22681889
Cellular Component	GO:0015629	actin cytoskeleton	H1-0	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000785	chromatin	H1-0	IDA		Human	PMID:19882353
Cellular Component	GO:0000791	euchromatin	H1-0	IDA		Human	PMID:15911621
Cellular Component	GO:0005794	Golgi apparatus	H1-0	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	H1-0	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	H1-0	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	H1-0	IDA		Human	PMID:21383955
Cellular Component	GO:0005634	nucleus	H1f0	IDA		Mouse	MGI:MGI:5559660|PMID:22868987
Cellular Component	GO:0005634	nucleus	H1f0	IDA		Mouse	PMID:9067599
Cellular Component	GO:0005634	nucleus	H1f0	IDA		Mouse	PMID:12606334
Cellular Component	GO:0017053	transcription repressor complex	H1-0	IDA		Human	PMID:19158276
Biological Process	GO:0031507	heterochromatin formation	H1-0	IGI	UniProtKB:P09429	Human	PMID:19158276
Biological Process	GO:2000679	positive regulation of transcription regulatory region DNA binding	H1-0	IMP		Human	PMID:19158276

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern