Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes H1-1
  • Mouse genes H1f1
  • Rat genes H1f1
  • Zfish genes histh1l3,si:ch211-103n10.5,si:ch73-368j24.11,si:dkey-108k21.21,si:dkey-23a13.17,zgc:110425,zgc:153405,zgc:163061
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set H1f1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031490	chromatin DNA binding	H1-1	IMP		Human	PMID:15911621
Molecular Function	GO:0003677	DNA binding	H1f1	IDA		Mouse	PMID:15562002
Molecular Function	GO:0008201	heparin binding	H1f1	IDA		Mouse	MGI:MGI:5882919|PMID:9664069
Molecular Function	GO:0005515	protein binding	H1-1	IPI	UniProtKB:Q57V41	Human	PMID:19895577
Molecular Function	GO:0005515	protein binding	H1-1	IPI	UniProtKB:O94811	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	H1-1	IPI	UniProtKB:Q8IUE6	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	H1-1	IPI	UniProtKB:O94811	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	H1-1	IPI	UniProtKB:Q8IUE6	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	H1f1	IPI	UniProtKB:P01267	Mouse	MGI:MGI:5882919|PMID:9664069
Molecular Function	GO:0005515	protein binding	H1f1	IPI	PR:Q99MD9	Mouse	PMID:10893414
Cellular Component	GO:0009986	cell surface	H1f1	IDA		Mouse	MGI:MGI:5882919|PMID:9664069
Cellular Component	GO:0000785	chromatin	H1-1	IDA		Human	PMID:19882353
Cellular Component	GO:0000791	euchromatin	H1-1	IDA		Human	PMID:15911621
Cellular Component	GO:0005654	nucleoplasm	H1-1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	H1f1	IDA		Mouse	MGI:MGI:5882919|PMID:9664069
Cellular Component	GO:0031982	vesicle	H1f1	IDA		Mouse	MGI:MGI:5882919|PMID:9664069
Biological Process	GO:0048260	positive regulation of receptor-mediated endocytosis	H1f1	IDA		Mouse	MGI:MGI:5882919|PMID:9664069
Biological Process	GO:0007283	spermatogenesis	H1f1	IGI	MGI:MGI:96945	Mouse	PMID:15051954

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern