Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes H1-2
  • Mouse genes H1f2
  • Rat genes H1f2
  • Zfish genes histh1l1,histh1l2,histh1l3,si:ch211-103n10.5,si:ch211-113a14.18,si:ch211-113a14.24,si:ch73-368j24.11,si:dkey-108k21.10,si:dkey-108k21.21,si:dkey-23a13.17,si:dkey-261m9.12,zgc:110216,zgc:110425,zgc:153405,zgc:163061
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set H1f2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031490	chromatin DNA binding	H1-2	IDA		Human	PMID:15911621
Molecular Function	GO:0003677	DNA binding	H1f2	IDA		Mouse	PMID:15562002
Molecular Function	GO:0005515	protein binding	H1-2	IPI	UniProtKB:Q8IWS0	Human	PMID:22720776
Molecular Function	GO:0005515	protein binding	H1f2	IPI	UniProtKB:O41974	Mouse	MGI:MGI:5787727|PMID:26581985
Molecular Function	GO:0005515	protein binding	H1f2	IPI	PR:Q99MD9	Mouse	PMID:10893414
Molecular Function	GO:0005515	protein binding	H1f2	IPI	PR:Q09XV5	Mouse	PMID:22083958
Molecular Function	GO:0003723	RNA binding	H1-2	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	H1-2	HDA		Human	PMID:22681889
Molecular Function	GO:0030527	structural constituent of chromatin	H1f2	IMP	MGI:MGI:2665852	Mouse	PMID:12808097
Cellular Component	GO:0000791	euchromatin	H1-2	IDA		Human	PMID:15911621
Cellular Component	GO:0000791	euchromatin	H1f2	IDA		Mouse	PMID:22083958
Cellular Component	GO:0005634	nucleus	H1-2	IDA		Human	PMID:21383955
Cellular Component	GO:0005634	nucleus	H1-2	IDA		Human	PMID:22720776
Biological Process	GO:0006325	chromatin organization	H1f2	IMP	MGI:MGI:2665852	Mouse	PMID:12808097
Biological Process	GO:0098532	histone H3-K27 trimethylation	H1f2	IGI	MGI:MGI:107502	Mouse	PMID:22701719
Biological Process	GO:0098532	histone H3-K27 trimethylation	H1f2	IGI	MGI:MGI:1931527	Mouse	PMID:22701719
Biological Process	GO:0080182	histone H3-K4 trimethylation	H1f2	IGI	MGI:MGI:1931527	Mouse	PMID:22701719
Biological Process	GO:0080182	histone H3-K4 trimethylation	H1f2	IGI	MGI:MGI:107502	Mouse	PMID:22701719
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	H1f2	IGI	MGI:MGI:1931527	Mouse	PMID:22083958
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	H1f2	IGI	MGI:MGI:107502	Mouse	PMID:22083958
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	H1f2	IMP		Mouse	PMID:22701719

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern