Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes H1-5
  • Mouse genes H1f5
  • Rat genes H1f5
  • Zfish genes histh1l2,si:ch211-113a14.18,si:ch211-113a14.24,si:ch73-368j24.12,si:dkey-108k21.10,si:dkey-261m9.12,zgc:110216
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set H1f5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031490	chromatin DNA binding	H1-5	IMP		Human	PMID:15911621
Molecular Function	GO:0031490	chromatin DNA binding	H1-5	IMP		Human	PMID:22956909
Molecular Function	GO:0003677	DNA binding	H1f5	IDA		Mouse	PMID:15562002
Molecular Function	GO:0003677	DNA binding	H1f5	IDA		Mouse	PMID:9182532
Molecular Function	GO:0042826	histone deacetylase binding	H1-5	IPI	UniProtKB:Q96EB6	Human	PMID:22956909
Molecular Function	GO:0005515	protein binding	H1-5	IPI	UniProtKB:Q9HC52	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	H1-5	IPI	UniProtKB:Q9HC52	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	H1f5	IPI	PR:P13297	Mouse	PMID:15192231
Molecular Function	GO:0003723	RNA binding	H1-5	HDA		Human	PMID:22658674
Cellular Component	GO:0000785	chromatin	H1-5	IDA		Human	PMID:19882353
Cellular Component	GO:0000785	chromatin	H1-5	IDA		Human	PMID:22956909
Cellular Component	GO:0005694	chromosome	H1-5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000792	heterochromatin	H1-5	IDA		Human	PMID:15911621
Cellular Component	GO:0005730	nucleolus	H1-5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	H1-5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	H1-5	IDA		Human	PMID:21383955
Biological Process	GO:0006325	chromatin organization	H1-5	IMP		Human	PMID:22956909
Biological Process	GO:0071169	establishment of protein localization to chromatin	H1-5	IMP		Human	PMID:22956909
Biological Process	GO:0007517	muscle organ development	H1f5	IPI	PR:P13297	Mouse	PMID:15192231
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	H1-5	IMP		Human	PMID:22956909
Biological Process	GO:0050821	protein stabilization	H1-5	IMP		Human	PMID:22956909

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern