Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HLA-A,HLA-B,HLA-C,HLA-E,HLA-F,HLA-G,HLA-H
  • Mouse genes H2-Q1
  • Rat genes RT1-A1,RT1-A2,RT1-CE10,RT1-CE15,RT1-CE2,RT1-CE4,RT1-CE7
  • Zfish genes mhc1lea,mhc1zaa,mhc1zba,mhc1zca,mhc1zea,mhc1zfa,mhc1zja,mhc1zka
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set H2-Q1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0071889	14-3-3 protein binding	HLA-F	IDA		Human	PMID:16709803
Molecular Function	GO:0030881	beta-2-microglobulin binding	HLA-H	IMP		Human	PMID:9162021
Molecular Function	GO:0030881	beta-2-microglobulin binding	HLA-A	IMP		Human	PMID:23566939
Molecular Function	GO:0030881	beta-2-microglobulin binding	HLA-A	IDA		Human	PMID:3309677
Molecular Function	GO:0030881	beta-2-microglobulin binding	HLA-A	IDA		Human	PMID:7694806
Molecular Function	GO:0030881	beta-2-microglobulin binding	HLA-A	IDA		Human	PMID:8805302
Molecular Function	GO:0030881	beta-2-microglobulin binding	HLA-A	IDA		Human	PMID:8906788
Molecular Function	GO:0030881	beta-2-microglobulin binding	HLA-E	IMP		Human	PMID:12411439
Molecular Function	GO:0030881	beta-2-microglobulin binding	HLA-E	IDA		Human	PMID:16474394
Molecular Function	GO:0030881	beta-2-microglobulin binding	HLA-E	IDA		Human	PMID:18339401
Molecular Function	GO:0030881	beta-2-microglobulin binding	HLA-E	IDA		Human	PMID:18448674
Molecular Function	GO:0030881	beta-2-microglobulin binding	HLA-E	IDA		Human	PMID:25631937
Molecular Function	GO:0030881	beta-2-microglobulin binding	HLA-E	IDA		Human	PMID:30087334
Molecular Function	GO:0030881	beta-2-microglobulin binding	HLA-F	IDA		Human	PMID:28636952
Molecular Function	GO:0030881	beta-2-microglobulin binding	RT1-A1	IPI	RGD:2189	Rat	PMID:11773898|RGD:2313503
Molecular Function	GO:0042610	CD8 receptor binding	HLA-A	IDA		Human	PMID:2784196
Molecular Function	GO:0042610	CD8 receptor binding	HLA-G	IDA		Human	PMID:12853576
Molecular Function	GO:0042802	identical protein binding	HLA-G	IPI	UniProtKB:P17693	Human	PMID:16455647
Molecular Function	GO:0042802	identical protein binding	HLA-G	IPI	UniProtKB:P17693	Human	PMID:18550825
Molecular Function	GO:0042288	MHC class I protein binding	HLA-E	IDA		Human	PMID:9754572
Molecular Function	GO:0046703	natural killer cell lectin-like receptor binding	HLA-E	IPI	UniProtKB:Q13241	Human	PMID:25631937
Molecular Function	GO:0042605	peptide antigen binding	HLA-B	IDA		Human	PMID:22031944
Molecular Function	GO:0042605	peptide antigen binding	HLA-B	IDA		Human	PMID:23646949
Molecular Function	GO:0042605	peptide antigen binding	HLA-A	IDA		Human	PMID:10435578
Molecular Function	GO:0042605	peptide antigen binding	HLA-A	IDA		Human	PMID:1402688
Molecular Function	GO:0042605	peptide antigen binding	HLA-A	IDA		Human	PMID:17189421
Molecular Function	GO:0042605	peptide antigen binding	HLA-A	IDA		Human	PMID:20364150
Molecular Function	GO:0042605	peptide antigen binding	HLA-A	IDA		Human	PMID:22031944
Molecular Function	GO:0042605	peptide antigen binding	HLA-A	IMP		Human	PMID:23566939
Molecular Function	GO:0042605	peptide antigen binding	HLA-A	IDA		Human	PMID:24643698
Molecular Function	GO:0042605	peptide antigen binding	HLA-A	IDA		Human	PMID:25631937
Molecular Function	GO:0042605	peptide antigen binding	HLA-A	IDA		Human	PMID:7504010
Molecular Function	GO:0042605	peptide antigen binding	HLA-A	IDA		Human	PMID:7694806
Molecular Function	GO:0042605	peptide antigen binding	HLA-A	IDA		Human	PMID:8805302
Molecular Function	GO:0042605	peptide antigen binding	HLA-A	IDA		Human	PMID:8839770
Molecular Function	GO:0042605	peptide antigen binding	HLA-A	IDA		Human	PMID:8906788
Molecular Function	GO:0042605	peptide antigen binding	HLA-A	IDA		Human	PMID:8955188
Molecular Function	GO:0042605	peptide antigen binding	HLA-A	IDA		Human	PMID:9177355
Molecular Function	GO:0042605	peptide antigen binding	HLA-C	IDA		Human	PMID:22031944
Molecular Function	GO:0042605	peptide antigen binding	HLA-E	IDA		Human	PMID:10799855
Molecular Function	GO:0042605	peptide antigen binding	HLA-E	IMP		Human	PMID:12411439
Molecular Function	GO:0042605	peptide antigen binding	HLA-E	IDA		Human	PMID:16474394
Molecular Function	GO:0042605	peptide antigen binding	HLA-E	IDA		Human	PMID:18083576
Molecular Function	GO:0042605	peptide antigen binding	HLA-E	IDA		Human	PMID:18339401
Molecular Function	GO:0042605	peptide antigen binding	HLA-E	IDA		Human	PMID:18448674
Molecular Function	GO:0042605	peptide antigen binding	HLA-E	IDA		Human	PMID:23335510
Molecular Function	GO:0042605	peptide antigen binding	HLA-E	IDA		Human	PMID:25631937
Molecular Function	GO:0042605	peptide antigen binding	HLA-E	IDA		Human	PMID:30087334
Molecular Function	GO:0042605	peptide antigen binding	HLA-E	IDA		Human	PMID:9427624
Molecular Function	GO:0042605	peptide antigen binding	HLA-E	IDA		Human	PMID:9486650
Molecular Function	GO:0042605	peptide antigen binding	HLA-E	IDA		Human	PMID:9754572
Molecular Function	GO:0042605	peptide antigen binding	HLA-G	IDA		Human	PMID:20122941
Molecular Function	GO:0042605	peptide antigen binding	HLA-G	IDA		Human	PMID:7584149
Molecular Function	GO:0042605	peptide antigen binding	HLA-G	IDA		Human	PMID:8805247
Molecular Function	GO:0042605	peptide antigen binding	HLA-F	IDA		Human	PMID:23851683
Molecular Function	GO:0042605	peptide antigen binding	HLA-F	IDA		Human	PMID:28636952
Molecular Function	GO:0042277	peptide binding	RT1-A1	IDA		Rat	PMID:10856297|RGD:2313508
Molecular Function	GO:0005515	protein binding	HLA-B	IPI	UniProtKB:P43628	Human	PMID:19858347
Molecular Function	GO:0005515	protein binding	HLA-B	IPI	UniProtKB:P43632	Human	PMID:19858347
Molecular Function	GO:0005515	protein binding	HLA-B	IPI	UniProtKB:Q9BX59	Human	PMID:26439010
Molecular Function	GO:0005515	protein binding	HLA-B	IPI	UniProtKB:Q14943	Human	PMID:27649529
Molecular Function	GO:0005515	protein binding	HLA-B	IPI	UniProtKB:Q8N423	Human	PMID:27649529
Molecular Function	GO:0005515	protein binding	HLA-B	IPI	UniProtKB:P43626	Human	PMID:28546555
Molecular Function	GO:0005515	protein binding	HLA-H	IPI	UniProtKB:P11142	Human	PMID:29764935
Molecular Function	GO:0005515	protein binding	HLA-A	IPI	UniProtKB:P03406	Human	PMID:12414957
Molecular Function	GO:0005515	protein binding	HLA-A	IPI	UniProtKB:Q15436	Human	PMID:20946353
Molecular Function	GO:0005515	protein binding	HLA-A	IPI	UniProtKB:Q9BX59	Human	PMID:23401559
Molecular Function	GO:0005515	protein binding	HLA-A	IPI	UniProtKB:Q9BX59	Human	PMID:26869717
Molecular Function	GO:0005515	protein binding	HLA-A	IPI	UniProtKB:P01732	Human	PMID:9177355
Molecular Function	GO:0005515	protein binding	HLA-C	IPI	UniProtKB:P43627	Human	PMID:18322206
Molecular Function	GO:0005515	protein binding	HLA-C	IPI	UniProtKB:P43628	Human	PMID:18322206
Molecular Function	GO:0005515	protein binding	HLA-C	IPI	UniProtKB:P43626	Human	PMID:18624290
Molecular Function	GO:0005515	protein binding	HLA-C	IPI	UniProtKB:Q14954	Human	PMID:18624290
Molecular Function	GO:0005515	protein binding	HLA-C	IPI	UniProtKB:F2VZG2	Human	PMID:19858347
Molecular Function	GO:0005515	protein binding	HLA-C	IPI	UniProtKB:P43626	Human	PMID:19858347
Molecular Function	GO:0005515	protein binding	HLA-C	IPI	UniProtKB:P43628	Human	PMID:19858347
Molecular Function	GO:0005515	protein binding	HLA-C	IPI	UniProtKB:P43632	Human	PMID:19858347
Molecular Function	GO:0005515	protein binding	HLA-C	IPI	UniProtKB:Q14943	Human	PMID:27649529
Molecular Function	GO:0005515	protein binding	HLA-C	IPI	UniProtKB:P43626	Human	PMID:28546555
Molecular Function	GO:0005515	protein binding	HLA-C	IPI	UniProtKB:Q14954	Human	PMID:28546555
Molecular Function	GO:0005515	protein binding	HLA-C	IPI	UniProtKB:Q14953	Human	PMID:28685972
Molecular Function	GO:0005515	protein binding	HLA-E	IPI	UniProtKB:Q13241	Human	PMID:18083576
Molecular Function	GO:0005515	protein binding	HLA-E	IPI	UniProtKB:P30511	Human	PMID:20483783
Molecular Function	GO:0005515	protein binding	HLA-E	IPI	UniProtKB:P61769	Human	PMID:9427624
Molecular Function	GO:0005515	protein binding	HLA-E	IPI	UniProtKB:Q03519	Human	PMID:9427624
Molecular Function	GO:0005515	protein binding	HLA-G	IPI	UniProtKB:Q99706	Human	PMID:10190900
Molecular Function	GO:0005515	protein binding	HLA-G	IPI	UniProtKB:P53618	Human	PMID:11520457
Molecular Function	GO:0005515	protein binding	HLA-G	IPI	UniProtKB:P53618	Human	PMID:12582157
Molecular Function	GO:0005515	protein binding	HLA-G	IPI	UniProtKB:P01732	Human	PMID:12853576
Molecular Function	GO:0005515	protein binding	HLA-G	IPI	UniProtKB:Q8N423	Human	PMID:12853576
Molecular Function	GO:0005515	protein binding	HLA-G	IPI	UniProtKB:Q8NHL6	Human	PMID:12853576
Molecular Function	GO:0005515	protein binding	HLA-G	IPI	UniProtKB:Q8NHL6	Human	PMID:12874224
Molecular Function	GO:0005515	protein binding	HLA-G	IPI	UniProtKB:Q99706	Human	PMID:16366734
Molecular Function	GO:0005515	protein binding	HLA-G	IPI	UniProtKB:Q8N423	Human	PMID:16455647
Molecular Function	GO:0005515	protein binding	HLA-G	IPI	UniProtKB:Q8NHL6	Human	PMID:16455647
Molecular Function	GO:0005515	protein binding	HLA-G	IPI	UniProtKB:O95971	Human	PMID:16809620
Molecular Function	GO:0005515	protein binding	HLA-G	IPI	UniProtKB:Q8N423	Human	PMID:17056715
Molecular Function	GO:0005515	protein binding	HLA-G	IPI	UniProtKB:Q8NHL6	Human	PMID:19583775
Molecular Function	GO:0005515	protein binding	HLA-G	IPI	UniProtKB:Q8N423	Human	PMID:24899623
Molecular Function	GO:0005515	protein binding	HLA-G	IPI	UniProtKB:P27797	Human	PMID:9640257
Molecular Function	GO:0005515	protein binding	HLA-F	IPI	UniProtKB:P27797	Human	PMID:10605026
Molecular Function	GO:0005515	protein binding	HLA-F	IPI	UniProtKB:Q8N423	Human	PMID:11169396
Molecular Function	GO:0005515	protein binding	HLA-F	IPI	UniProtKB:Q8NHL6	Human	PMID:11169396
Molecular Function	GO:0005515	protein binding	HLA-F	IPI	UniProtKB:P13747	Human	PMID:20483783
Molecular Function	GO:0005515	protein binding	HLA-F	IPI	UniProtKB:P43630	Human	PMID:24018270
Molecular Function	GO:0005515	protein binding	HLA-F	IPI	UniProtKB:P43632	Human	PMID:24018270
Molecular Function	GO:0005515	protein binding	HLA-F	IPI	UniProtKB:P43629	Human	PMID:27455421
Molecular Function	GO:0005515	protein binding	HLA-F	IPI	UniProtKB:P43630	Human	PMID:27455421
Molecular Function	GO:0005515	protein binding	HLA-F	IPI	UniProtKB:Q14943	Human	PMID:27455421
Molecular Function	GO:0005515	protein binding	HLA-F	IPI	UniProtKB:P43629	Human	PMID:27649529
Molecular Function	GO:0005515	protein binding	HLA-F	IPI	UniProtKB:P43632	Human	PMID:27649529
Molecular Function	GO:0005515	protein binding	HLA-F	IPI	UniProtKB:Q14943	Human	PMID:27649529
Molecular Function	GO:0005515	protein binding	HLA-F	IPI	UniProtKB:Q8NHL6	Human	PMID:28636952
Molecular Function	GO:0005515	protein binding	RT1-A2	IPI	RGD:3818	Rat	PMID:12817008|RGD:2313509
Molecular Function	GO:0005515	protein binding	RT1-A1	IPI	RGD:3818	Rat	PMID:12817008|RGD:2313509
Molecular Function	GO:0042803	protein homodimerization activity	HLA-G	IDA		Human	PMID:12874224
Molecular Function	GO:0042803	protein homodimerization activity	HLA-G	IDA		Human	PMID:22802125
Molecular Function	GO:0044877	protein-containing complex binding	RT1-A1	IPI	RGD:735892	Rat	PMID:8597563|RGD:2313510
Molecular Function	GO:0051087	protein-folding chaperone binding	HLA-B	IPI	UniProtKB:P27797	Human	PMID:15056662
Molecular Function	GO:0003723	RNA binding	HLA-A	HDA		Human	PMID:22658674
Molecular Function	GO:0005102	signaling receptor binding	HLA-B	IPI	UniProtKB:Q8N423	Human	PMID:20008523
Molecular Function	GO:0005102	signaling receptor binding	HLA-B	IPI	UniProtKB:Q13241	Human	PMID:8046333
Molecular Function	GO:0005102	signaling receptor binding	HLA-A	IPI	UniProtKB:Q8N423	Human	PMID:19124746
Molecular Function	GO:0005102	signaling receptor binding	HLA-A	IPI	UniProtKB:Q8NHL6	Human	PMID:19124746
Molecular Function	GO:0005102	signaling receptor binding	HLA-E	IPI	UniProtKB:P26715	Human	PMID:18448674
Molecular Function	GO:0005102	signaling receptor binding	HLA-E	IPI	UniProtKB:P26717	Human	PMID:18448674
Molecular Function	GO:0005102	signaling receptor binding	HLA-E	IPI	UniProtKB:Q13241	Human	PMID:18448674
Molecular Function	GO:0005102	signaling receptor binding	HLA-G	IPI	UniProtKB:Q8N423	Human	PMID:20702625
Molecular Function	GO:0005102	signaling receptor binding	HLA-G	IPI	UniProtKB:Q8NHL6	Human	PMID:20702625
Molecular Function	GO:0005102	signaling receptor binding	HLA-G	IPI	UniProtKB:Q8N423	Human	PMID:22802125
Molecular Function	GO:0042608	T cell receptor binding	HLA-A	IDA		Human	PMID:10435578
Molecular Function	GO:0042608	T cell receptor binding	HLA-A	IDA		Human	PMID:8906788
Molecular Function	GO:0042608	T cell receptor binding	HLA-A	IDA		Human	PMID:8955188
Molecular Function	GO:0042608	T cell receptor binding	HLA-E	IDA		Human	PMID:16474394
Molecular Function	GO:0046977	TAP binding	HLA-B	IDA		Human	PMID:8617941
Molecular Function	GO:0046977	TAP binding	HLA-A	IDA		Human	PMID:8617941
Molecular Function	GO:0046977	TAP binding	HLA-A	IDA		Human	PMID:8805302
Molecular Function	GO:0046977	TAP binding	HLA-C	IDA		Human	PMID:8617941
Molecular Function	GO:0046977	TAP binding	HLA-C	IDA		Human	PMID:8805302
Molecular Function	GO:0062061	TAP complex binding	HLA-A	IDA		Human	PMID:8630735
Molecular Function	GO:0046978	TAP1 binding	HLA-F	IPI	UniProtKB:Q03518	Human	PMID:10605026
Molecular Function	GO:0046979	TAP2 binding	HLA-F	IPI	UniProtKB:Q03519	Human	PMID:10605026
Cellular Component	GO:0009986	cell surface	HLA-B	HDA		Human	PMID:19581412
Cellular Component	GO:0009986	cell surface	HLA-B	IDA		Human	PMID:22031944
Cellular Component	GO:0009986	cell surface	HLA-B	IDA		Human	PMID:9754572
Cellular Component	GO:0009986	cell surface	HLA-H	IMP		Human	PMID:9162021
Cellular Component	GO:0009986	cell surface	HLA-A	IDA		Human	PMID:22031944
Cellular Component	GO:0009986	cell surface	HLA-A	IDA		Human	PMID:8805302
Cellular Component	GO:0009986	cell surface	HLA-A	IDA		Human	PMID:8839770
Cellular Component	GO:0009986	cell surface	HLA-C	IDA		Human	PMID:22031944
Cellular Component	GO:0009986	cell surface	HLA-C	IDA		Human	PMID:9754572
Cellular Component	GO:0009986	cell surface	HLA-E	IDA		Human	PMID:12411439
Cellular Component	GO:0009986	cell surface	HLA-E	IDA		Human	PMID:25631937
Cellular Component	GO:0009986	cell surface	HLA-E	IDA		Human	PMID:9754572
Cellular Component	GO:0009986	cell surface	HLA-F	IDA		Human	PMID:20865824
Cellular Component	GO:0033106	cis-Golgi network membrane	HLA-G	IDA		Human	PMID:12582157
Cellular Component	GO:0005769	early endosome	HLA-G	IDA		Human	PMID:16366734
Cellular Component	GO:0031901	early endosome membrane	HLA-F	IDA		Human	PMID:23851683
Cellular Component	GO:0005783	endoplasmic reticulum	HLA-B	IDA		Human	PMID:20946353
Cellular Component	GO:0005783	endoplasmic reticulum	HLA-A	IDA		Human	PMID:20946353
Cellular Component	GO:0005783	endoplasmic reticulum	HLA-A	IDA		Human	PMID:8805302
Cellular Component	GO:0005783	endoplasmic reticulum	HLA-C	IDA		Human	PMID:20946353
Cellular Component	GO:0005783	endoplasmic reticulum	HLA-F	IDA		Human	PMID:10605026
Cellular Component	GO:0070971	endoplasmic reticulum exit site	HLA-A	IDA		Human	PMID:20946353
Cellular Component	GO:0070062	extracellular exosome	HLA-B	HDA		Human	PMID:12519789
Cellular Component	GO:0070062	extracellular exosome	HLA-B	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	HLA-B	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	HLA-B	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	HLA-A	HDA		Human	PMID:11487543
Cellular Component	GO:0070062	extracellular exosome	HLA-A	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	HLA-A	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	HLA-C	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	HLA-E	HDA		Human	PMID:20458337
Cellular Component	GO:0005794	Golgi apparatus	HLA-B	IDA		Human	PMID:20946353
Cellular Component	GO:0005794	Golgi apparatus	HLA-A	IDA		Human	PMID:20946353
Cellular Component	GO:0005794	Golgi apparatus	HLA-C	IDA		Human	PMID:20946353
Cellular Component	GO:0005797	Golgi medial cisterna	HLA-A	IDA		Human	PMID:8805302
Cellular Component	GO:0000139	Golgi membrane	HLA-F	IDA		Human	PMID:16709803
Cellular Component	GO:0005765	lysosomal membrane	HLA-F	IDA		Human	PMID:23851683
Cellular Component	GO:0016020	membrane	HLA-B	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	HLA-A	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	HLA-C	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	HLA-G	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	HLA-F	HDA		Human	PMID:19946888
Cellular Component	GO:0042824	MHC class I peptide loading complex	HLA-A	IDA		Human	PMID:21263072
Cellular Component	GO:0042612	MHC class I protein complex	HLA-B	IDA		Human	PMID:22031944
Cellular Component	GO:0042612	MHC class I protein complex	HLA-A	IDA		Human	PMID:22031944
Cellular Component	GO:0042612	MHC class I protein complex	HLA-A	IDA		Human	PMID:25631937
Cellular Component	GO:0042612	MHC class I protein complex	HLA-A	IDA		Human	PMID:7694806
Cellular Component	GO:0042612	MHC class I protein complex	HLA-A	IDA		Human	PMID:8805302
Cellular Component	GO:0042612	MHC class I protein complex	HLA-A	IDA		Human	PMID:8906788
Cellular Component	GO:0042612	MHC class I protein complex	HLA-C	IDA		Human	PMID:22031944
Cellular Component	GO:0042612	MHC class I protein complex	HLA-E	IDA		Human	PMID:12411439
Cellular Component	GO:0042612	MHC class I protein complex	HLA-E	IDA		Human	PMID:16474394
Cellular Component	GO:0042612	MHC class I protein complex	HLA-E	IDA		Human	PMID:18448674
Cellular Component	GO:0032398	MHC class Ib protein complex	HLA-E	IDA		Human	PMID:23335510
Cellular Component	GO:0032398	MHC class Ib protein complex	HLA-E	IDA		Human	PMID:25631937
Cellular Component	GO:0032398	MHC class Ib protein complex	HLA-E	IDA		Human	PMID:30087334
Cellular Component	GO:0032398	MHC class Ib protein complex	HLA-E	IDA		Human	PMID:9427624
Cellular Component	GO:0032398	MHC class Ib protein complex	HLA-F	IDA		Human	PMID:28636952
Cellular Component	GO:0005886	plasma membrane	HLA-A	IDA		Human	PMID:2784196
Cellular Component	GO:0005886	plasma membrane	HLA-A	IDA		Human	PMID:8630735
Cellular Component	GO:0005886	plasma membrane	HLA-E	IDA		Human	PMID:17179229
Cellular Component	GO:0005886	plasma membrane	HLA-E	IDA		Human	PMID:9427624
Cellular Component	GO:0005886	plasma membrane	HLA-G	IDA		Human	PMID:11290782
Cellular Component	GO:0005886	plasma membrane	HLA-G	IDA		Human	PMID:12582157
Cellular Component	GO:0005886	plasma membrane	HLA-F	IDA		Human	PMID:16709803
Cellular Component	GO:0005886	plasma membrane	HLA-F	IDA		Human	PMID:23851683
Cellular Component	GO:0005886	plasma membrane	HLA-F	IDA		Human	PMID:27455421
Biological Process	GO:0002250	adaptive immune response	HLA-E	IDA		Human	PMID:25631937
Biological Process	GO:0019731	antibacterial humoral response	HLA-A	IDA		Human	PMID:25631937
Biological Process	GO:0019731	antibacterial humoral response	HLA-E	IDA		Human	PMID:25631937
Biological Process	GO:0019882	antigen processing and presentation	H2-Q1	IMP		Mouse	PMID:20038604
Biological Process	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	HLA-A	IDA		Human	PMID:1402688
Biological Process	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	HLA-A	IDA		Human	PMID:20364150
Biological Process	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	HLA-A	IDA		Human	PMID:24643698
Biological Process	GO:0002485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	HLA-A	IMP		Human	PMID:8630735
Biological Process	GO:0002486	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	HLA-B	IDA		Human	PMID:22031944
Biological Process	GO:0002486	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	HLA-A	IDA		Human	PMID:22031944
Biological Process	GO:0002486	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	HLA-C	IDA		Human	PMID:22031944
Biological Process	GO:0002476	antigen processing and presentation of endogenous peptide antigen via MHC class Ib	HLA-E	IDA		Human	PMID:9754572
Biological Process	GO:0002476	antigen processing and presentation of endogenous peptide antigen via MHC class Ib	HLA-G	IDA		Human	PMID:7584149
Biological Process	GO:0002476	antigen processing and presentation of endogenous peptide antigen via MHC class Ib	HLA-G	IDA		Human	PMID:8805247
Biological Process	GO:0002476	antigen processing and presentation of endogenous peptide antigen via MHC class Ib	HLA-F	IDA		Human	PMID:28636952
Biological Process	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	HLA-A	IDA		Human	PMID:12138174
Biological Process	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	HLA-A	IDA		Human	PMID:7504010
Biological Process	GO:0002477	antigen processing and presentation of exogenous peptide antigen via MHC class Ib	HLA-E	IDA		Human	PMID:30087334
Biological Process	GO:0002477	antigen processing and presentation of exogenous peptide antigen via MHC class Ib	HLA-F	IDA		Human	PMID:23851683
Biological Process	GO:0036037	CD8-positive, alpha-beta T cell activation	HLA-A	IDA		Human	PMID:12138174
Biological Process	GO:0036037	CD8-positive, alpha-beta T cell activation	HLA-A	IDA		Human	PMID:1402688
Biological Process	GO:0036037	CD8-positive, alpha-beta T cell activation	HLA-A	IDA		Human	PMID:17189421
Biological Process	GO:0036037	CD8-positive, alpha-beta T cell activation	HLA-A	IDA		Human	PMID:20364150
Biological Process	GO:0036037	CD8-positive, alpha-beta T cell activation	HLA-A	IDA		Human	PMID:2784196
Biological Process	GO:0036037	CD8-positive, alpha-beta T cell activation	HLA-A	IDA		Human	PMID:7504010
Biological Process	GO:0036037	CD8-positive, alpha-beta T cell activation	HLA-A	IDA		Human	PMID:8630735
Biological Process	GO:0036037	CD8-positive, alpha-beta T cell activation	HLA-E	IDA		Human	PMID:25631937
Biological Process	GO:0050830	defense response to Gram-positive bacterium	HLA-A	IDA		Human	PMID:25631937
Biological Process	GO:0050830	defense response to Gram-positive bacterium	HLA-E	IDA		Human	PMID:25631937
Biological Process	GO:0016045	detection of bacterium	HLA-B	IMP		Human	PMID:22321387
Biological Process	GO:0016045	detection of bacterium	HLA-A	IMP		Human	PMID:22321387
Biological Process	GO:0006955	immune response	HLA-B	IMP		Human	PMID:22321387
Biological Process	GO:0006955	immune response	HLA-A	IMP		Human	PMID:22321387
Biological Process	GO:0002767	immune response-inhibiting cell surface receptor signaling pathway	HLA-G	IDA		Human	PMID:20702625
Biological Process	GO:0002519	natural killer cell tolerance induction	HLA-E	IDA		Human	PMID:9486650
Biological Process	GO:0016525	negative regulation of angiogenesis	HLA-G	IDA		Human	PMID:16809620
Biological Process	GO:2001199	negative regulation of dendritic cell differentiation	HLA-G	IDA		Human	PMID:20702625
Biological Process	GO:0070317	negative regulation of G0 to G1 transition	HLA-G	IDA		Human	PMID:24453251
Biological Process	GO:0002728	negative regulation of natural killer cell cytokine production	HLA-F	IDA		Human	PMID:24018270
Biological Process	GO:0043322	negative regulation of natural killer cell degranulation	HLA-F	IDA		Human	PMID:24018270
Biological Process	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	HLA-E	IDA		Human	PMID:10799855
Biological Process	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	HLA-E	IDA		Human	PMID:17179229
Biological Process	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	HLA-E	IDA		Human	PMID:23335510
Biological Process	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	HLA-E	IDA		Human	PMID:9486650
Biological Process	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	HLA-G	IDA		Human	PMID:10190900
Biological Process	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	HLA-G	IMP		Human	PMID:12874224
Biological Process	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	HLA-F	IDA		Human	PMID:24018270
Biological Process	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	RT1-A1	IMP		Rat	PMID:10837412|RGD:2313500
Biological Process	GO:1901215	negative regulation of neuron death	HLA-F	IDA		Human	PMID:26928464
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	HLA-G	IDA		Human	PMID:24453251
Biological Process	GO:0002725	negative regulation of T cell cytokine production	HLA-F	IDA		Human	PMID:24018270
Biological Process	GO:0001915	negative regulation of T cell mediated cytotoxicity	HLA-G	IDA		Human	PMID:11290782
Biological Process	GO:0042130	negative regulation of T cell proliferation	HLA-G	IDA		Human	PMID:20702625
Biological Process	GO:0002451	peripheral B cell tolerance induction	HLA-G	IDA		Human	PMID:24453251
Biological Process	GO:0001815	positive regulation of antibody-dependent cellular cytotoxicity	HLA-E	IDA		Human	PMID:30134159
Biological Process	GO:2001187	positive regulation of CD8-positive, alpha-beta T cell activation	HLA-A	IDA		Human	PMID:24643698
Biological Process	GO:2001187	positive regulation of CD8-positive, alpha-beta T cell activation	HLA-E	IDA		Human	PMID:28676677
Biological Process	GO:2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation	HLA-A	IDA		Human	PMID:25631937
Biological Process	GO:2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation	HLA-E	IDA		Human	PMID:25631937
Biological Process	GO:2000774	positive regulation of cellular senescence	HLA-G	IDA		Human	PMID:23184984
Biological Process	GO:2000353	positive regulation of endothelial cell apoptotic process	HLA-G	IDA		Human	PMID:16809620
Biological Process	GO:0002639	positive regulation of immunoglobulin production	HLA-E	IDA		Human	PMID:25631937
Biological Process	GO:0032735	positive regulation of interleukin-12 production	HLA-G	IDA		Human	PMID:20702625
Biological Process	GO:0032736	positive regulation of interleukin-13 production	HLA-E	IDA		Human	PMID:25631937
Biological Process	GO:0032753	positive regulation of interleukin-4 production	HLA-E	IDA		Human	PMID:25631937
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	HLA-G	IDA		Human	PMID:19304799
Biological Process	GO:2000568	positive regulation of memory T cell activation	HLA-A	IDA		Human	PMID:22031944
Biological Process	GO:0002729	positive regulation of natural killer cell cytokine production	HLA-E	IDA		Human	PMID:30134159
Biological Process	GO:0002729	positive regulation of natural killer cell cytokine production	HLA-G	IDA		Human	PMID:16366734
Biological Process	GO:0002729	positive regulation of natural killer cell cytokine production	HLA-G	IDA		Human	PMID:19304799
Biological Process	GO:0002729	positive regulation of natural killer cell cytokine production	HLA-G	IDA		Human	PMID:23184984
Biological Process	GO:0002729	positive regulation of natural killer cell cytokine production	HLA-F	IDA		Human	PMID:27455421
Biological Process	GO:0043323	positive regulation of natural killer cell degranulation	HLA-F	IDA		Human	PMID:27455421
Biological Process	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	HLA-E	IDA		Human	PMID:23335510
Biological Process	GO:0002717	positive regulation of natural killer cell mediated immunity	HLA-E	IDA		Human	PMID:9754572
Biological Process	GO:0032819	positive regulation of natural killer cell proliferation	HLA-E	IDA		Human	PMID:30134159
Biological Process	GO:0045591	positive regulation of regulatory T cell differentiation	HLA-G	IMP		Human	PMID:20448110
Biological Process	GO:0002726	positive regulation of T cell cytokine production	HLA-A	IDA		Human	PMID:24643698
Biological Process	GO:0001916	positive regulation of T cell mediated cytotoxicity	HLA-B	IDA		Human	PMID:2420472
Biological Process	GO:0001916	positive regulation of T cell mediated cytotoxicity	HLA-A	IDA		Human	PMID:22031944
Biological Process	GO:0001916	positive regulation of T cell mediated cytotoxicity	HLA-A	IDA		Human	PMID:2420472
Biological Process	GO:0001916	positive regulation of T cell mediated cytotoxicity	HLA-A	IDA		Human	PMID:25631937
Biological Process	GO:0001916	positive regulation of T cell mediated cytotoxicity	HLA-A	IDA		Human	PMID:8805302
Biological Process	GO:0001916	positive regulation of T cell mediated cytotoxicity	HLA-E	IDA		Human	PMID:25631937
Biological Process	GO:0001916	positive regulation of T cell mediated cytotoxicity	HLA-F	IMP		Human	PMID:23851683
Biological Process	GO:0001916	positive regulation of T cell mediated cytotoxicity	RT1-A1	IDA		Rat	PMID:11773898|RGD:2313503
Biological Process	GO:0002666	positive regulation of T cell tolerance induction	HLA-G	IMP		Human	PMID:20448110
Biological Process	GO:0002645	positive regulation of tolerance induction	HLA-G	IMP		Human	PMID:22802125
Biological Process	GO:0002657	positive regulation of tolerance induction to nonself antigen	RT1-A1	IMP		Rat	PMID:16000395|RGD:2313504
Biological Process	GO:0032759	positive regulation of TRAIL production	HLA-E	IDA		Human	PMID:25631937
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	HLA-E	IDA		Human	PMID:25631937
Biological Process	GO:0032729	positive regulation of type II interferon production	HLA-A	IDA		Human	PMID:22031944
Biological Process	GO:0042270	protection from natural killer cell mediated cytotoxicity	HLA-B	IDA		Human	PMID:18502829
Biological Process	GO:0042270	protection from natural killer cell mediated cytotoxicity	HLA-B	IDA		Human	PMID:2784569
Biological Process	GO:0042270	protection from natural killer cell mediated cytotoxicity	HLA-B	IDA		Human	PMID:8046333
Biological Process	GO:0042270	protection from natural killer cell mediated cytotoxicity	HLA-A	IDA		Human	PMID:18502829
Biological Process	GO:0042270	protection from natural killer cell mediated cytotoxicity	HLA-A	IDA		Human	PMID:8839770
Biological Process	GO:0042270	protection from natural killer cell mediated cytotoxicity	HLA-E	IDA		Human	PMID:25631937
Biological Process	GO:0042270	protection from natural killer cell mediated cytotoxicity	HLA-E	IDA		Human	PMID:9754572
Biological Process	GO:0042270	protection from natural killer cell mediated cytotoxicity	HLA-G	IDA		Human	PMID:11290782
Biological Process	GO:0070207	protein homotrimerization	HLA-G	IDA		Human	PMID:12874224
Biological Process	GO:2001198	regulation of dendritic cell differentiation	HLA-B	IMP		Human	PMID:20008523
Biological Process	GO:0032655	regulation of interleukin-12 production	HLA-B	IMP		Human	PMID:20008523
Biological Process	GO:0032675	regulation of interleukin-6 production	HLA-B	IMP		Human	PMID:20008523
Biological Process	GO:0002715	regulation of natural killer cell mediated immunity	HLA-E	IDA		Human	PMID:18448674
Biological Process	GO:0002667	regulation of T cell anergy	HLA-B	IMP		Human	PMID:20008523
Biological Process	GO:0001913	T cell mediated cytotoxicity	HLA-A	IDA		Human	PMID:7504010
Biological Process	GO:0002419	T cell mediated cytotoxicity directed against tumor cell target	HLA-A	IDA		Human	PMID:1402688
Biological Process	GO:0002419	T cell mediated cytotoxicity directed against tumor cell target	HLA-A	IDA		Human	PMID:17189421
Biological Process	GO:0002419	T cell mediated cytotoxicity directed against tumor cell target	HLA-A	IDA		Human	PMID:20364150
Biological Process	GO:0050852	T cell receptor signaling pathway	HLA-A	IDA		Human	PMID:10435578
Biological Process	GO:0002517	T cell tolerance induction	RT1-A1	IMP		Rat	PMID:16000395|RGD:2313504

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern