Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes H2AZ1
  • Mouse genes H2az1
  • Rat genes H2az1
  • Zfish genes h2az2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set H2az1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031490	chromatin DNA binding	H2AZ1	IDA		Human	PMID:19834540
Molecular Function	GO:0031490	chromatin DNA binding	H2AZ1	IDA		Human	PMID:23637611
Molecular Function	GO:0031492	nucleosomal DNA binding	H2AZ1	IDA		Human	PMID:19633671
Molecular Function	GO:0005515	protein binding	H2AZ1	IPI	UniProtKB:O43257	Human	PMID:20473270
Molecular Function	GO:0005515	protein binding	H2AZ1	IPI	UniProtKB:Q9GZN1	Human	PMID:20473270
Molecular Function	GO:0005515	protein binding	H2AZ1	IPI	UniProtKB:Q8IWS0	Human	PMID:22720776
Molecular Function	GO:0005515	protein binding	H2AZ1	IPI	UniProtKB:O43257	Human	PMID:24463511
Molecular Function	GO:0005515	protein binding	H2AZ1	IPI	UniProtKB:Q9GZN1	Human	PMID:24463511
Molecular Function	GO:0005515	protein binding	H2AZ1	IPI	UniProtKB:P07954	Human	PMID:26237645
Molecular Function	GO:0005515	protein binding	H2AZ1	IPI	UniProtKB:P07954-2	Human	PMID:26237645
Molecular Function	GO:0005515	protein binding	H2AZ1	IPI	UniProtKB:P06899,UniProtKB:Q15906	Human	PMID:26974126
Molecular Function	GO:0005515	protein binding	H2AZ1	IPI	UniProtKB:Q96N64	Human	PMID:28645917
Molecular Function	GO:0005515	protein binding	H2AZ1	IPI	UniProtKB:Q01831	Human	PMID:31527837
Molecular Function	GO:0005515	protein binding	H2AZ1	IPI	UniProtKB:O14656-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	H2AZ1	IPI	UniProtKB:P01023	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	H2AZ1	IPI	UniProtKB:P50570-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	H2az1	IPI	UniProtKB:Q62481	Mouse	MGI:MGI:6287047|PMID:30842416
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	H2AZ1	IDA		Human	PMID:19633671
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	H2AZ1	IDA		Human	PMID:19834540
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	H2AZ1	IDA		Human	PMID:23637611
Molecular Function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	H2AZ1	IDA		Human	PMID:19633671
Molecular Function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	H2AZ1	IDA		Human	PMID:23637611
Cellular Component	GO:0000791	euchromatin	H2AZ1	IDA		Human	PMID:19834540
Cellular Component	GO:0000791	euchromatin	H2AZ1	IDA		Human	PMID:23637611
Cellular Component	GO:0070062	extracellular exosome	H2AZ1	HDA		Human	PMID:23533145
Cellular Component	GO:0000792	heterochromatin	H2AZ1	IDA		Human	PMID:19834540
Cellular Component	GO:0000786	nucleosome	H2AZ1	IPI		Human	PMID:24311584
Cellular Component	GO:0005634	nucleus	H2AZ1	IDA		Human	PMID:11331621
Cellular Component	GO:0005634	nucleus	H2AZ1	IDA		Human	PMID:16319397
Cellular Component	GO:0005634	nucleus	H2AZ1	IDA		Human	PMID:16457589
Cellular Component	GO:0005634	nucleus	H2AZ1	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	H2AZ1	IDA		Human	PMID:22720776
Cellular Component	GO:0005634	nucleus	H2az1	IDA		Mouse	PMID:10716735
Cellular Component	GO:0005634	nucleus	H2az1	IDA		Rat	PMID:24471919|RGD:9588479
Cellular Component	GO:0005634	nucleus	H2az1	IDA		Rat	PMID:2760138|RGD:9588478
Biological Process	GO:0071392	cellular response to estradiol stimulus	H2AZ1	IMP		Human	PMID:23637611
Biological Process	GO:0032869	cellular response to insulin stimulus	H2az1	IDA		Rat	PMID:24471919|RGD:9588479
Biological Process	GO:0043045	DNA methylation involved in embryo development	h2az2b	IMP	ZFIN:ZDB-MRPHLNO-180507-2	Zfish	PMID:29099280
Biological Process	GO:0043045	DNA methylation involved in embryo development	h2az2b	IGI	ZFIN:ZDB-GENE-990714-15	Zfish	PMID:29099280
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	H2AZ1	IMP		Human	PMID:19834540
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	H2AZ1	IMP		Human	PMID:23637611

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern