Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes H2BC11
  • Mouse genes H2bc21
  • Rat genes Hist2h2be
  • Zfish genes hist2h2l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set H2bc21

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001530	lipopolysaccharide binding	H2BC11	IDA		Human	PMID:11859126
Molecular Function	GO:0005515	protein binding	H2BC11	IPI	UniProtKB:P04908	Human	PMID:20498094
Molecular Function	GO:0005515	protein binding	H2BC11	IPI	UniProtKB:P04908	Human	PMID:21743476
Molecular Function	GO:0005515	protein binding	H2BC11	IPI	UniProtKB:P0C0S5,UniProtKB:Q15906	Human	PMID:26974126
Molecular Function	GO:0005515	protein binding	H2BC11	IPI	UniProtKB:P04908	Human	PMID:31142837
Molecular Function	GO:0005515	protein binding	H2bc21	IPI	PR:Q80ZK9	Mouse	PMID:17767906
Cellular Component	GO:0043505	CENP-A containing nucleosome	H2BC11	IPI		Human	PMID:21743476
Cellular Component	GO:0000785	chromatin	hist2h2l	IDA		Zfish	PMID:22155959
Cellular Component	GO:0005829	cytosol	H2BC11	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005615	extracellular space	H2BC11	IDA		Human	PMID:11859126
Cellular Component	GO:0005615	extracellular space	H2BC11	IDA		Human	PMID:12860195
Cellular Component	GO:0005654	nucleoplasm	H2BC11	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000786	nucleosome	H2BC11	IPI		Human	PMID:20498094
Cellular Component	GO:0000786	nucleosome	H2BC11	IPI		Human	PMID:21812398
Cellular Component	GO:0000786	nucleosome	H2BC11	IPI		Human	PMID:24311584
Cellular Component	GO:0000786	nucleosome	H2BC11	IPI		Human	PMID:26694698
Cellular Component	GO:0005634	nucleus	H2BC11	IDA		Human	PMID:16319397
Cellular Component	GO:0005634	nucleus	H2BC11	HDA		Human	PMID:21630459
Cellular Component	GO:0005886	plasma membrane	H2BC11	IDA		Human	PMID:11859126
Biological Process	GO:0019731	antibacterial humoral response	H2BC11	IDA		Human	PMID:12860195
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	H2BC11	IDA		Human	PMID:11859126
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	H2BC11	IDA		Human	PMID:12860195
Biological Process	GO:0050829	defense response to Gram-negative bacterium	H2BC11	IDA		Human	PMID:11859126
Biological Process	GO:0050830	defense response to Gram-positive bacterium	H2BC11	IDA		Human	PMID:11859126
Biological Process	GO:0050830	defense response to Gram-positive bacterium	H2BC11	IDA		Human	PMID:12860195
Biological Process	GO:0002227	innate immune response in mucosa	H2BC11	IDA		Human	PMID:12860195
Biological Process	GO:0031640	killing of cells of another organism	H2BC11	IDA		Human	PMID:11859126
Biological Process	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	H2BC11	IDA		Human	PMID:11859126

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern