Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes H2BC10,H2BC5,H2BC6,H2BC8
  • Mouse genes H2bc4
  • Rat genes Hist1h2bc,Hist1h2bo,Hist1h2bq,LOC100364835,LOC100365043,LOC100910200,LOC684797
  • Zfish genes hist2h2l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set H2bc4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	H2BC10	IPI	UniProtKB:P62807	Human	PMID:25954010
Molecular Function	GO:0005515	protein binding	H2BC5	IPI	UniProtKB:P16104	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	H2BC5	IPI	UniProtKB:P16104	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	H2BC10	IPI	UniProtKB:Q13625-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	H2BC10	IPI	UniProtKB:Q12888	Human	PMID:27462807
Molecular Function	GO:0005515	protein binding	H2BC10	IPI	UniProtKB:Q96CW1	Human	PMID:32296183
Cellular Component	GO:0000785	chromatin	hist2h2l	IDA		Zfish	PMID:22155959
Cellular Component	GO:0005829	cytosol	H2BC5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	H2BC10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	H2BC5	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	H2BC10	HDA		Human	PMID:20458337
Cellular Component	GO:0005615	extracellular space	H2BC10	IDA		Human	PMID:12860195
Cellular Component	GO:0005654	nucleoplasm	H2BC5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	H2BC10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	H2BC5	IDA		Human	PMID:16319397
Cellular Component	GO:0005634	nucleus	H2BC5	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	H2BC10	HDA		Human	PMID:21630459
Biological Process	GO:0019731	antibacterial humoral response	H2BC10	IDA		Human	PMID:12860195
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	H2BC10	IDA		Human	PMID:12860195
Biological Process	GO:0050830	defense response to Gram-positive bacterium	H2BC10	IDA		Human	PMID:12860195
Biological Process	GO:0002227	innate immune response in mucosa	H2BC10	IDA		Human	PMID:12860195

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern