Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HACL1
  • Mouse genes Hacl1
  • Rat genes Hacl1
  • Zfish genes hacl1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hacl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0106360	2-hydroxy-3-methylhexadecanoyl-CoA lyase activity	HACL1	IMP		Human	PMID:21708296
Molecular Function	GO:0005524	ATP binding	HACL1	IDA		Human	PMID:15644336
Molecular Function	GO:0016830	carbon-carbon lyase activity	HACL1	IDA		Human	PMID:10468558
Molecular Function	GO:0016830	carbon-carbon lyase activity	HACL1	IDA		Human	PMID:15644336
Molecular Function	GO:0016830	carbon-carbon lyase activity	HACL1	IMP		Human	PMID:28289220
Molecular Function	GO:0016830	carbon-carbon lyase activity	Hacl1	IMP		Mouse	MGI:MGI:6105330|PMID:28629946
Molecular Function	GO:0016830	carbon-carbon lyase activity	Hacl1	IDA		Rat	PMID:10468558|RGD:708588
Molecular Function	GO:0042802	identical protein binding	HACL1	IPI	UniProtKB:Q9UJ83	Human	PMID:16189514
Molecular Function	GO:0042802	identical protein binding	HACL1	IPI	UniProtKB:Q9UJ83	Human	PMID:21708296
Molecular Function	GO:0042802	identical protein binding	HACL1	IPI	UniProtKB:Q9UJ83	Human	PMID:25416956
Molecular Function	GO:0016829	lyase activity	Hacl1	IDA		Mouse	PMID:11171065
Molecular Function	GO:0000287	magnesium ion binding	HACL1	IDA		Human	PMID:15644336
Molecular Function	GO:0005515	protein binding	HACL1	IPI	UniProtKB:Q96E35	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	HACL1	IPI	UniProtKB:Q8N7X4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HACL1	IPI	UniProtKB:Q96E35	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HACL1	IPI	UniProtKB:Q96E35	Human	PMID:32296183
Molecular Function	GO:0030976	thiamine pyrophosphate binding	HACL1	IDA		Human	PMID:10468558
Molecular Function	GO:0030976	thiamine pyrophosphate binding	HACL1	IMP		Human	PMID:21708296
Molecular Function	GO:0030976	thiamine pyrophosphate binding	Hacl1	IDA		Rat	PMID:10468558|RGD:708588
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	HACL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HACL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005777	peroxisome	HACL1	IDA		Human	PMID:10468558
Cellular Component	GO:0005777	peroxisome	HACL1	IDA		Human	PMID:14561759
Cellular Component	GO:0005777	peroxisome	HACL1	IDA		Human	PMID:21708296
Cellular Component	GO:0005777	peroxisome	HACL1	IDA		Human	PMID:28289220
Cellular Component	GO:0005777	peroxisome	Hacl1	IDA		Rat	PMID:10468558|RGD:708588
Biological Process	GO:0001561	fatty acid alpha-oxidation	HACL1	IDA		Human	PMID:10468558
Biological Process	GO:0001561	fatty acid alpha-oxidation	HACL1	IDA		Human	PMID:15644336
Biological Process	GO:0001561	fatty acid alpha-oxidation	HACL1	IDA		Human	PMID:21708296
Biological Process	GO:0001561	fatty acid alpha-oxidation	HACL1	IDA		Human	PMID:28289220
Biological Process	GO:0001561	fatty acid alpha-oxidation	Hacl1	IMP		Mouse	MGI:MGI:6105330|PMID:28629946
Biological Process	GO:0001561	fatty acid alpha-oxidation	Hacl1	IDA		Rat	PMID:10468558|RGD:708588
Biological Process	GO:0006631	fatty acid metabolic process	HACL1	IDA		Human	PMID:28289220
Biological Process	GO:0006629	lipid metabolic process	Hacl1	IDA		Mouse	PMID:11171065
Biological Process	GO:0097089	methyl-branched fatty acid metabolic process	HACL1	IDA		Human	PMID:21708296
Biological Process	GO:0097089	methyl-branched fatty acid metabolic process	HACL1	IDA		Human	PMID:28289220
Biological Process	GO:0097089	methyl-branched fatty acid metabolic process	Hacl1	IDA		Rat	PMID:10468558|RGD:708588
Biological Process	GO:1903512	phytanic acid metabolic process	HACL1	IDA		Human	PMID:28289220
Biological Process	GO:0006625	protein targeting to peroxisome	HACL1	IMP		Human	PMID:10468558

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern