Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HADHA
  • Mouse genes Hadha
  • Rat genes Hadha
  • Zfish genes hadhaa,hadhab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hadha

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0018812	3-hydroxyacyl-CoA dehydratase activity	Hadha	IDA		Rat	PMID:1730633|RGD:1600572
Molecular Function	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity	Hadha	IDA		Rat	PMID:1730633|RGD:1600572
Molecular Function	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity	Hadha	IMP		Rat	PMID:8253773|RGD:632874
Molecular Function	GO:0003988	acetyl-CoA C-acyltransferase activity	Hadha	IDA		Rat	PMID:1730633|RGD:1600572
Molecular Function	GO:0004300	enoyl-CoA hydratase activity	Hadha	IDA		Rat	PMID:1730633|RGD:1600572
Molecular Function	GO:0004300	enoyl-CoA hydratase activity	Hadha	IMP		Rat	PMID:8253773|RGD:632874
Molecular Function	GO:0000062	fatty-acyl-CoA binding	Hadha	IDA		Rat	PMID:1730633|RGD:1600572
Molecular Function	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity	Hadha	IDA		Mouse	PMID:15240869
Molecular Function	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity	Hadha	IDA		Rat	PMID:1730633|RGD:1600572
Molecular Function	GO:0051287	NAD binding	Hadha	IDA		Rat	PMID:1730633|RGD:1600572
Molecular Function	GO:0005515	protein binding	HADHA	IPI	UniProtKB:O95166	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	HADHA	IPI	UniProtKB:P60520	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	HADHA	IPI	UniProtKB:Q9GZQ8	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	HADHA	IPI	UniProtKB:Q9H0R8	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	HADHA	IPI	UniProtKB:P55084	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HADHA	IPI	UniProtKB:P55084	Human	PMID:29915090
Molecular Function	GO:0005515	protein binding	HADHA	IPI	UniProtKB:P55084	Human	PMID:30850536
Molecular Function	GO:0005515	protein binding	HADHA	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Hadha	IPI	UniProtKB:Q8BT35	Mouse	MGI:MGI:6278482|PMID:29949755
Molecular Function	GO:0044877	protein-containing complex binding	Hadha	IMP		Rat	PMID:20132223|RGD:5688153
Cellular Component	GO:0016507	mitochondrial fatty acid beta-oxidation multienzyme complex	HADHA	IPI		Human	PMID:29915090
Cellular Component	GO:0016507	mitochondrial fatty acid beta-oxidation multienzyme complex	Hadha	IDA		Rat	PMID:1730633|RGD:1600572
Cellular Component	GO:0005743	mitochondrial inner membrane	HADHA	IDA		Human	PMID:29915090
Cellular Component	GO:0005743	mitochondrial inner membrane	Hadha	HDA		Mouse	PMID:12865426
Cellular Component	GO:0042645	mitochondrial nucleoid	HADHA	IDA		Human	PMID:18063578
Cellular Component	GO:0005739	mitochondrion	HADHA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	HADHA	HDA		Human	PMID:20833797
Cellular Component	GO:0005739	mitochondrion	HADHA	IDA		Human	PMID:23152787
Cellular Component	GO:0005739	mitochondrion	Hadha	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Hadha	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Hadha	IDA		Rat	PMID:1730633|RGD:1600572
Biological Process	GO:0035965	cardiolipin acyl-chain remodeling	HADHA	IDA		Human	PMID:23152787
Biological Process	GO:0006635	fatty acid beta-oxidation	HADHA	IDA		Human	PMID:29915090
Biological Process	GO:0006635	fatty acid beta-oxidation	Hadha	IMP	MGI:MGI:2137697	Mouse	PMID:11390422
Biological Process	GO:0006635	fatty acid beta-oxidation	Hadha	IDA		Rat	PMID:1730633|RGD:1600572
Biological Process	GO:0009617	response to bacterium	hadhaa	IDA		Zfish	PMID:17055441
Biological Process	GO:0032868	response to insulin	Hadha	IMP	MGI:MGI:2137697	Mouse	PMID:15887119
Biological Process	GO:0009410	response to xenobiotic stimulus	Hadha	IDA		Rat	PMID:12176671|RGD:1599883

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern