Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Hap1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes HAP1
- Mouse genes Hap1
- Rat genes Hap1
- Zfish genes hap1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hap1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0048403	brain-derived neurotrophic factor binding	Hap1	IDA		Rat	PMID:19996106\|RGD:10047154
Molecular Function	GO:0048403	brain-derived neurotrophic factor binding	Hap1	IDA		Rat	PMID:21357693\|RGD:10047187
Molecular Function	GO:0042802	identical protein binding	Hap1	IPI	UniProtKB:P54256	Rat	PMID:9361024\|RGD:10047270
Molecular Function	GO:0042802	identical protein binding	Hap1	IPI	UniProtKB:P54256	Rat	PMID:9798945\|RGD:10047369
Molecular Function	GO:0042802	identical protein binding	Hap1	IPI	UniProtKB:P54256-1	Rat	PMID:9798945\|RGD:10047369
Molecular Function	GO:0042802	identical protein binding	Hap1	IPI	UniProtKB:P54256-2	Rat	PMID:9798945\|RGD:10047369
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:P42858	Human	PMID:20515468
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:P54252-1	Human	PMID:21386698
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q8N157	Human	PMID:23532844
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q9H0I3	Human	PMID:25074808
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:A6NI15	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:O14964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:P09067	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:P56524-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:P60520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q07002	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q15973	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q16512	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q53TS8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q5T619	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q6NYC8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q6P2D0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q7Z3I7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q86XF7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q8IYE1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q8TAB5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q8TCX5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q8WTP8-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q8WWY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q96NC0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q9BWG6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q9ULM2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q9Y247	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:Q9Y2P0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HAP1	IPI	UniProtKB:P42858	Human	PMID:7477378
Molecular Function	GO:0005515	protein binding	Hap1	IPI	UniProtKB:Q8K3E5	Mouse	MGI:MGI:5498436\|PMID:23532844
Molecular Function	GO:0005515	protein binding	Hap1	IPI	UniProtKB:B2GV74	Mouse	MGI:MGI:5284788\|PMID:16339760
Molecular Function	GO:0005515	protein binding	Hap1	IPI	UniProtKB:Q8K3E5	Mouse	MGI:MGI:4939576\|PMID:21146532
Molecular Function	GO:0005515	protein binding	Hap1	IPI	PR:O08788	Mouse	PMID:15242649
Molecular Function	GO:0005515	protein binding	Hap1	IPI	PR:P42859	Mouse	PMID:15242649
Molecular Function	GO:0005515	protein binding	Hap1	IPI	PR:P42859	Mouse	PMID:9599014
Molecular Function	GO:0005515	protein binding	Hap1	IPI	UniProtKB:Q9JJ50	Rat	PMID:12021262\|RGD:625566
Molecular Function	GO:0005515	protein binding	Hap1	IPI	UniProtKB:P29994	Rat	PMID:12873381\|RGD:6482800
Molecular Function	GO:0005515	protein binding	Hap1	IPI	UniProtKB:P63104	Rat	PMID:17166838\|RGD:10047162
Molecular Function	GO:0005515	protein binding	Hap1	IPI	UniProtKB:P42858	Rat	PMID:18615096\|RGD:10047351
Molecular Function	GO:0005515	protein binding	Hap1	IPI	UniProtKB:Q14203	Rat	PMID:18615096\|RGD:10047351
Molecular Function	GO:0005515	protein binding	Hap1	IPI	RGD:1303040	Rat	PMID:23658157\|RGD:11537396
Molecular Function	GO:0005515	protein binding	Hap1	IPI	RGD:621865	Rat	PMID:9285789\|RGD:728800
Molecular Function	GO:0005515	protein binding	Hap1	IPI	UniProtKB:P42858	Rat	PMID:9285789\|RGD:728800
Molecular Function	GO:0005515	protein binding	Hap1	IPI	UniProtKB:P97924	Rat	PMID:9285789\|RGD:728800
Molecular Function	GO:0005515	protein binding	Hap1	IPI	UniProtKB:Q14203	Rat	PMID:9361024\|RGD:10047270
Molecular Function	GO:0005515	protein binding	Hap1	IPI	UniProtKB:Q15154	Rat	PMID:9361024\|RGD:10047270
Molecular Function	GO:0005515	protein binding	Hap1	IPI	RGD:68337	Rat	PMID:9454836\|RGD:10403028
Molecular Function	GO:0005515	protein binding	Hap1	IPI	UniProtKB:P42858	Rat	PMID:9798945\|RGD:10047369
Molecular Function	GO:0019904	protein domain specific binding	Hap1	IPI	RGD:2933	Rat	PMID:12873381\|RGD:6482800
Molecular Function	GO:0005102	signaling receptor binding	Hap1	IPI	RGD:2933	Rat	PMID:12873381\|RGD:6482800
Molecular Function	GO:0044325	transmembrane transporter binding	Hap1	IDA		Rat	PMID:12873381\|RGD:6482800
Cellular Component	GO:0005776	autophagosome	Hap1	IDA		Mouse	MGI:MGI:5553183\|PMID:24453320
Cellular Component	GO:0043679	axon terminus	Hap1	IDA		Rat	PMID:10924259\|RGD:728841
Cellular Component	GO:0005814	centriole	Hap1	IDA		Mouse	PMID:21985783
Cellular Component	GO:0005813	centrosome	Hap1	IDA		Mouse	MGI:MGI:5298413\|PMID:21985783
Cellular Component	GO:0005737	cytoplasm	Hap1	IDA		Rat	PMID:17166838\|RGD:10047162
Cellular Component	GO:0031410	cytoplasmic vesicle	Hap1	IDA		Mouse	PMID:15242649
Cellular Component	GO:0005829	cytosol	HAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030425	dendrite	Hap1	IDA		Rat	PMID:10924259\|RGD:728841
Cellular Component	GO:0098982	GABA-ergic synapse	Hap1	IDA		Rat	PMID:15310851\|RGD:13702182
Cellular Component	GO:0098982	GABA-ergic synapse	Hap1	IMP		Rat	PMID:15310851\|RGD:13702182
Cellular Component	GO:0030426	growth cone	Hap1	IDA		Rat	PMID:10924259\|RGD:728841
Cellular Component	GO:0016234	inclusion body	HAP1	IDA		Human	PMID:21386698
Cellular Component	GO:0043005	neuron projection	Hap1	IDA		Rat	PMID:10924259\|RGD:728841
Cellular Component	GO:0005730	nucleolus	HAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Hap1	IDA		Rat	PMID:10924259\|RGD:728841
Cellular Component	GO:0099524	postsynaptic cytosol	Hap1	IDA		Rat	PMID:9742138\|RGD:13702459
Cellular Component	GO:0099523	presynaptic cytosol	Hap1	IDA		Rat	PMID:9742138\|RGD:13702459
Biological Process	GO:0008089	anterograde axonal transport	Hap1	IMP		Mouse	MGI:MGI:5560429\|PMID:24355921
Biological Process	GO:0008089	anterograde axonal transport	Hap1	IMP		Rat	PMID:19996106\|RGD:10047154
Biological Process	GO:0008089	anterograde axonal transport	Hap1	IMP		Rat	PMID:22731248\|RGD:10047200
Biological Process	GO:0071363	cellular response to growth factor stimulus	Hap1	IEP		Rat	PMID:10924259\|RGD:728841
Biological Process	GO:0021549	cerebellum development	Hap1	IMP		Mouse	MGI:MGI:3814764\|PMID:18636121
Biological Process	GO:0021979	hypothalamus cell differentiation	Hap1	IMP		Mouse	MGI:MGI:5560429\|PMID:24355921
Biological Process	GO:1902430	negative regulation of amyloid-beta formation	Hap1	IMP		Rat	PMID:22731248\|RGD:10047200
Biological Process	GO:0022008	neurogenesis	Hap1	IMP		Mouse	MGI:MGI:3814764\|PMID:18636121
Biological Process	GO:0031175	neuron projection development	Hap1	IDA		Rat	PMID:17166838\|RGD:10047162
Biological Process	GO:0048011	neurotrophin TRK receptor signaling pathway	Hap1	IMP		Mouse	MGI:MGI:5560429\|PMID:24355921
Biological Process	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	Hap1	IMP		Rat	PMID:12890790\|RGD:10047165
Biological Process	GO:0090261	positive regulation of inclusion body assembly	Hap1	IDA		Rat	PMID:9798945\|RGD:10047369
Biological Process	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	Hap1	IMP		Mouse	MGI:MGI:3603715\|PMID:15379999
Biological Process	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	Hap1	IDA		Rat	PMID:12873381\|RGD:6482800
Biological Process	GO:0050769	positive regulation of neurogenesis	Hap1	IMP		Mouse	MGI:MGI:5560429\|PMID:24355921
Biological Process	GO:0010976	positive regulation of neuron projection development	Hap1	IDA		Rat	PMID:10924259\|RGD:728841
Biological Process	GO:0032901	positive regulation of neurotrophin production	Hap1	IMP		Rat	PMID:19996106\|RGD:10047154
Biological Process	GO:0032901	positive regulation of neurotrophin production	Hap1	IDA		Rat	PMID:21357693\|RGD:10047187
Biological Process	GO:1902857	positive regulation of non-motile cilium assembly	Hap1	IMP		Mouse	PMID:21985783
Biological Process	GO:0032230	positive regulation of synaptic transmission, GABAergic	Hap1	IDA		Rat	PMID:20152113\|RGD:10047142
Biological Process	GO:0032230	positive regulation of synaptic transmission, GABAergic	Hap1	IMP		Rat	PMID:20152113\|RGD:10047142
Biological Process	GO:0008104	protein localization	HAP1	IMP		Human	PMID:18922795
Biological Process	GO:0017157	regulation of exocytosis	Hap1	IMP		Mouse	MGI:MGI:5583012\|PMID:24366265
Biological Process	GO:1902513	regulation of organelle transport along microtubule	Hap1	IMP		Mouse	MGI:MGI:5553183\|PMID:24453320
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Hap1	IDA		Rat	PMID:15310851\|RGD:13702182
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Hap1	IEP		Rat	PMID:15310851\|RGD:13702182
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Hap1	IMP		Rat	PMID:15310851\|RGD:13702182
Biological Process	GO:0008090	retrograde axonal transport	Hap1	IMP		Rat	PMID:19996106\|RGD:10047154
Biological Process	GO:0008090	retrograde axonal transport	Hap1	IMP		Rat	PMID:22731248\|RGD:10047200
Biological Process	GO:0047496	vesicle transport along microtubule	Hap1	IMP		Mouse	PMID:15242649

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.