Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HBE1,HBG1,HBG2
  • Mouse genes Hbb-bh1
  • Rat genes Hbg1
  • Zfish genes hbba2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hbb-bh1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0020037	heme binding	Hbg1	IDA		Rat	PMID:8882731|RGD:1600581
Molecular Function	GO:0031721	hemoglobin alpha binding	Hbg1	IDA		Rat	PMID:8882731|RGD:1600581
Molecular Function	GO:0005344	oxygen carrier activity	HBG1	IDA		Human	PMID:22096240
Molecular Function	GO:0005344	oxygen carrier activity	HBG2	IDA		Human	PMID:19065339
Molecular Function	GO:0005515	protein binding	HBE1	IPI	UniProtKB:P02008	Human	PMID:11159543
Molecular Function	GO:0005515	protein binding	HBE1	IPI	UniProtKB:P69905	Human	PMID:11159543
Molecular Function	GO:0005515	protein binding	HBE1	IPI	UniProtKB:P02008	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HBE1	IPI	UniProtKB:P09105	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HBE1	IPI	UniProtKB:P69905	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HBG2	IPI	UniProtKB:P09105	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HBG2	IPI	UniProtKB:P69905	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HBG2	IPI	UniProtKB:Q6B0K9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HBG2	IPI	UniProtKB:Q9NQW7-3	Human	PMID:32296183
Molecular Function	GO:0044877	protein-containing complex binding	Hbg1	IDA		Rat	PMID:8882731|RGD:1600581
Cellular Component	GO:0072562	blood microparticle	HBE1	HDA		Human	PMID:22516433
Cellular Component	GO:0072562	blood microparticle	HBG2	HDA		Human	PMID:22516433
Cellular Component	GO:0005833	hemoglobin complex	HBE1	IPI		Human	PMID:11159543
Cellular Component	GO:0005833	hemoglobin complex	HBE1	IPI		Human	PMID:9665850
Cellular Component	GO:0005833	hemoglobin complex	HBG1	IPI		Human	PMID:11514664
Cellular Component	GO:0005833	hemoglobin complex	HBG1	IPI		Human	PMID:6683087
Cellular Component	GO:0005833	hemoglobin complex	HBG1	IPI		Human	PMID:881729
Cellular Component	GO:0005833	hemoglobin complex	HBG2	IPI		Human	PMID:6683087
Cellular Component	GO:0005833	hemoglobin complex	HBG2	IPI		Human	PMID:881729
Cellular Component	GO:0005833	hemoglobin complex	Hbg1	IDA		Rat	PMID:8882731|RGD:1600581
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hbb-bh1	IGI	MGI:MGI:96027	Mouse	PMID:17077320
Biological Process	GO:0015671	oxygen transport	HBE1	IDA		Human	PMID:11159543
Biological Process	GO:0015671	oxygen transport	HBG1	IDA		Human	PMID:22096240
Biological Process	GO:0015671	oxygen transport	HBG1	IDA		Human	PMID:7543751
Biological Process	GO:0015671	oxygen transport	HBG2	IDA		Human	PMID:19065339
Biological Process	GO:0015671	oxygen transport	HBG2	IDA		Human	PMID:7543751

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern