Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HBP1
  • Mouse genes Hbp1
  • Rat genes Hbp1
  • Zfish genes hbp1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hbp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Hbp1	IDA		Rat	PMID:15024088|RGD:12911006
Molecular Function	GO:0005515	protein binding	HBP1	IPI	UniProtKB:P06400	Human	PMID:23859194
Molecular Function	GO:0005515	protein binding	Hbp1	IPI	UniProtKB:P13405	Mouse	MGI:MGI:3687408|PMID:9178770
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Hbp1	IDA		Rat	PMID:15024088|RGD:12911006
Cellular Component	GO:0016607	nuclear speck	HBP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HBP1	IDA		Human	GO_REF:0000052
Biological Process	GO:0032369	negative regulation of lipid transport	Hbp1	IDA		Mouse	MGI:MGI:5754467|PMID:24675724
Biological Process	GO:1903427	negative regulation of reactive oxygen species biosynthetic process	Hbp1	IDA		Mouse	MGI:MGI:5754467|PMID:24675724
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hbp1	IDA		Rat	PMID:15024088|RGD:12911006
Biological Process	GO:0043268	positive regulation of potassium ion transport	Hbp1	IDA		Rat	PMID:7937077|RGD:632907

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern