Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HCAR2,HCAR3
  • Mouse genes Hcar2
  • Rat genes Hcar2
  • Zfish genes hcar1-3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hcar2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004930	G protein-coupled receptor activity	Hcar2	IDA		Mouse	PMID:19047060
Molecular Function	GO:0005525	GTP binding	Hcar2	IDA		Mouse	PMID:12646212
Molecular Function	GO:0070553	nicotinic acid receptor activity	Hcar2	IDA		Rat	PMID:19141678|RGD:8553927
Molecular Function	GO:0001614	purinergic nucleotide receptor activity	Hcar2	IDA		Mouse	PMID:12646212
Cellular Component	GO:0030054	cell junction	HCAR3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030054	cell junction	HCAR2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	Hcar2	IDA		Mouse	PMID:19047060
Cellular Component	GO:0016020	membrane	Hcar2	IDA		Mouse	PMID:12646212
Cellular Component	GO:0005886	plasma membrane	HCAR2	IDA		Human	PMID:17932499
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Hcar2	IDA		Mouse	PMID:19047060
Biological Process	GO:0050995	negative regulation of lipid catabolic process	Hcar2	IDA		Rat	PMID:19141678|RGD:8553927
Biological Process	GO:0001781	neutrophil apoptotic process	HCAR2	IDA		Human	PMID:17932499
Biological Process	GO:0070165	positive regulation of adiponectin secretion	Hcar2	IDA		Rat	PMID:19141678|RGD:8553927
Biological Process	GO:0033031	positive regulation of neutrophil apoptotic process	HCAR2	IDA		Human	PMID:17932499

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern