Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HCFC1
  • Mouse genes Hcfc1
  • Rat genes Hcfc1
  • Zfish genes hcfc1a,hcfc1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hcfc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	HCFC1	HDA		Human	PMID:25468996
Molecular Function	GO:0003682	chromatin binding	HCFC1	IDA		Human	PMID:21285374
Molecular Function	GO:0031490	chromatin DNA binding	Hcfc1	IDA		Mouse	PMID:22878500
Molecular Function	GO:0140297	DNA-binding transcription factor binding	HCFC1	IPI	UniProtKB:P08047	Human	PMID:10976766
Molecular Function	GO:0140297	DNA-binding transcription factor binding	HCFC1	IPI	UniProtKB:P06492	Human	PMID:9199328
Molecular Function	GO:0042802	identical protein binding	HCFC1	IPI	UniProtKB:P51610	Human	PMID:12670868
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:O43889	Human	PMID:10629049
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:P14859	Human	PMID:10629049
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q06546	Human	PMID:10675337
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q06547	Human	PMID:10675337
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q06547-2	Human	PMID:10675337
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:O43889	Human	PMID:10871379
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q9NS37	Human	PMID:10871379
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:P08047	Human	PMID:10976766
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q13105	Human	PMID:12244100
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:O15047	Human	PMID:12670868
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:O15294	Human	PMID:12670868
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:O75182	Human	PMID:12670868
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:O75446	Human	PMID:12670868
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:P08047	Human	PMID:12670868
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:P61964	Human	PMID:12670868
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q13547	Human	PMID:12670868
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q92769	Human	PMID:12670868
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q96ST3	Human	PMID:12670868
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q9H7L9	Human	PMID:12670868
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q9UBL3	Human	PMID:12670868
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:P11161	Human	PMID:14532282
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q16254	Human	PMID:14532282
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:O43889	Human	PMID:15705566
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q9NS37	Human	PMID:15705566
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:P61964	Human	PMID:15960975
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:O15047	Human	PMID:17998332
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:O43889-2	Human	PMID:18391022
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q9NS37	Human	PMID:18391022
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q96EK4	Human	PMID:18585351
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q92560	Human	PMID:19188440
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q92560	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q92560	Human	PMID:19815555
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q9UPP1	Human	PMID:20622854
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:O15294	Human	PMID:21285374
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:O15294	Human	PMID:21295698
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:O43524	Human	PMID:21909281
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q96EB6	Human	PMID:21909281
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:O43151	Human	PMID:23353889
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q6N021	Human	PMID:23353889
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q01094|UniProtKB:Q8IZD2	Human	PMID:23629655
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q9UBL3	Human	PMID:23870121
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q92560	Human	PMID:24211834
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:P61964	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q9UBL3	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:O15294	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:P61964	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q92560	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:Q9NVV9	Human	PMID:28486698
Molecular Function	GO:0005515	protein binding	HCFC1	IPI	UniProtKB:O43889-2	Human	PMID:9271389
Molecular Function	GO:0005515	protein binding	Hcfc1	IPI	UniProtKB:Q3URK3	Mouse	MGI:MGI:5487471|PMID:23352454
Molecular Function	GO:0005515	protein binding	Hcfc1	IPI	UniProtKB:Q99PU7	Mouse	PMID:22878500
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	HCFC1	IPI	UniProtKB:Q01094,UniProtKB:Q8IZD2	Human	PMID:23629655
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Hcfc1	IDA		Mouse	PMID:18836447
Molecular Function	GO:0003713	transcription coactivator activity	HCFC1	IMP		Human	PMID:10675337
Molecular Function	GO:0003713	transcription coactivator activity	HCFC1	IMP		Human	PMID:23629655
Cellular Component	GO:0030424	axon	Hcfc1	IDA		Rat	PMID:22383875|RGD:9588483
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Hcfc1	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Hcfc1	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0005737	cytoplasm	HCFC1	IDA		Human	PMID:10623756
Cellular Component	GO:0005737	cytoplasm	HCFC1	IDA		Human	PMID:20091349
Cellular Component	GO:0005737	cytoplasm	Hcfc1	IDA		Mouse	MGI:MGI:3687690|PMID:9990006
Cellular Component	GO:0005737	cytoplasm	Hcfc1	IDA		Rat	PMID:22383875|RGD:9588483
Cellular Component	GO:0030425	dendrite	Hcfc1	IDA		Rat	PMID:22383875|RGD:9588483
Cellular Component	GO:0000123	histone acetyltransferase complex	HCFC1	IDA		Human	PMID:20018852
Cellular Component	GO:0016020	membrane	HCFC1	HDA		Human	PMID:19946888
Cellular Component	GO:0071339	MLL1 complex	HCFC1	IPI		Human	PMID:23508102
Cellular Component	GO:0071339	MLL1 complex	HCFC1	IDA		Human	PMID:15960975
Cellular Component	GO:0044665	MLL1/2 complex	HCFC1	IPI		Human	PMID:23508102
Cellular Component	GO:0043025	neuronal cell body	HCFC1	IDA		Human	PMID:20091349
Cellular Component	GO:0044545	NSL complex	HCFC1	IDA		Human	PMID:20018852
Cellular Component	GO:0000228	nuclear chromosome	Hcfc1	IDA		Rat	PMID:24250814|RGD:151356618
Cellular Component	GO:0005654	nucleoplasm	HCFC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	HCFC1	IDA		Human	PMID:10623756
Cellular Component	GO:0005634	nucleus	HCFC1	IDA		Human	PMID:19188440
Cellular Component	GO:0005634	nucleus	HCFC1	IDA		Human	PMID:20091349
Cellular Component	GO:0005634	nucleus	HCFC1	IDA		Human	PMID:21285374
Cellular Component	GO:0005634	nucleus	HCFC1	IDA		Human	PMID:23629655
Cellular Component	GO:0005634	nucleus	HCFC1	IDA		Human	PMID:7876203
Cellular Component	GO:0005634	nucleus	Hcfc1	IDA		Mouse	MGI:MGI:3687690|PMID:9990006
Cellular Component	GO:0005634	nucleus	Hcfc1	IDA		Mouse	MGI:MGI:5568315|PMID:24250814
Cellular Component	GO:0005634	nucleus	Hcfc1	IDA		Rat	PMID:22383875|RGD:9588483
Cellular Component	GO:0032991	protein-containing complex	HCFC1	IDA		Human	PMID:23629655
Cellular Component	GO:0048188	Set1C/COMPASS complex	HCFC1	IPI		Human	PMID:23508102
Cellular Component	GO:0048188	Set1C/COMPASS complex	HCFC1	IDA		Human	PMID:17998332
Cellular Component	GO:0048188	Set1C/COMPASS complex	HCFC1	IDA		Human	PMID:18838538
Biological Process	GO:0001835	blastocyst hatching	Hcfc1	IMP		Mouse	PMID:27869233
Biological Process	GO:0007420	brain development	hcfc1a	IMP	ZFIN:ZDB-GENO-210824-1	Zfish	PMID:32522152
Biological Process	GO:0071407	cellular response to organic cyclic compound	Hcfc1	IEP		Rat	PMID:22383875|RGD:9588483
Biological Process	GO:0002062	chondrocyte differentiation	hcfc1b	IMP	ZFIN:ZDB-MRPHLNO-150309-3	Zfish	PMID:25281006
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	hcfc1b	IMP	ZFIN:ZDB-MRPHLNO-150309-3	Zfish	PMID:25281006
Biological Process	GO:0043984	histone H4-K16 acetylation	HCFC1	IDA		Human	PMID:20018852
Biological Process	GO:0043981	histone H4-K5 acetylation	HCFC1	IDA		Human	PMID:20018852
Biological Process	GO:0043982	histone H4-K8 acetylation	HCFC1	IDA		Human	PMID:20018852
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hcfc1	IMP		Rat	PMID:21909281|RGD:8553379
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	HCFC1	IMP		Human	PMID:23629655
Biological Process	GO:0010628	positive regulation of gene expression	HCFC1	IDA		Human	PMID:21285374
Biological Process	GO:0051571	positive regulation of histone H3-K4 methylation	HCFC1	IDA		Human	PMID:24244196
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Hcfc1	IMP		Rat	PMID:24250814|RGD:151356618
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HCFC1	IDA		Human	PMID:20200153
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hcfc1	IMP		Rat	PMID:24250814|RGD:151356618
Biological Process	GO:0050821	protein stabilization	HCFC1	IDA		Human	PMID:21285374
Biological Process	GO:0006355	regulation of DNA-templated transcription	HCFC1	IDA		Human	PMID:12670868
Biological Process	GO:1900095	regulation of dosage compensation by inactivation of X chromosome	Hcfc1	IDA		Mouse	MGI:MGI:6207704|PMID:24842875
Biological Process	GO:0043254	regulation of protein-containing complex assembly	HCFC1	IDA		Human	PMID:10675337
Biological Process	GO:0019046	release from viral latency	Hcfc1	IDA		Mouse	MGI:MGI:3687690|PMID:9990006

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern