Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HCRTR1
  • Mouse genes Hcrtr1
  • Rat genes Hcrtr1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hcrtr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016499	orexin receptor activity	HCRTR1	IDA		Human	PMID:26950369
Molecular Function	GO:0016499	orexin receptor activity	Hcrtr1	IDA		Rat	PMID:12890892|RGD:1642020
Molecular Function	GO:0017046	peptide hormone binding	Hcrtr1	IDA		Rat	PMID:12890892|RGD:1642020
Molecular Function	GO:0005515	protein binding	Hcrtr1	IPI	PR:P56387	Mouse	PMID:22028875
Molecular Function	GO:0005515	protein binding	Hcrtr1	IPI	PR:P51807	Mouse	PMID:22028875
Cellular Component	GO:0005886	plasma membrane	HCRTR1	IDA		Human	PMID:26950369
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Hcrtr1	IDA		Rat	PMID:12890892|RGD:1642020
Biological Process	GO:0007218	neuropeptide signaling pathway	HCRTR1	IDA		Human	PMID:26950369
Biological Process	GO:0007218	neuropeptide signaling pathway	Hcrtr1	IDA		Rat	PMID:12697296|RGD:730811
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Hcrtr1	IDA		Mouse	PMID:22028875
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	HCRTR1	IDA		Human	PMID:26950369

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern