Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Hdac4

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes HDAC4
- Mouse genes Hdac4
- Rat genes Hdac4
- Zfish genes hdac4
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hdac4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Hdac4	IDA		Mouse	PMID:24768298
Molecular Function	GO:0003677	DNA binding	Hdac4	IDA		Mouse	PMID:16260608
Molecular Function	GO:0140297	DNA-binding transcription factor binding	HDAC4	IPI	UniProtKB:Q8CFN5	Human	PMID:10983972
Molecular Function	GO:0140297	DNA-binding transcription factor binding	HDAC4	IPI	UniProtKB:O75376	Human	PMID:11804585
Molecular Function	GO:0140297	DNA-binding transcription factor binding	Hdac4	IPI	UniProtKB:Q02078	Mouse	MGI:MGI:5009201\|PMID:10748098
Molecular Function	GO:0004407	histone deacetylase activity	HDAC4	IDA		Human	PMID:10220385
Molecular Function	GO:0004407	histone deacetylase activity	HDAC4	IDA		Human	PMID:10869435
Molecular Function	GO:0042826	histone deacetylase binding	HDAC4	IPI	UniProtKB:O15379	Human	PMID:10869435
Molecular Function	GO:0042826	histone deacetylase binding	HDAC4	IPI	UniProtKB:Q9UKV0	Human	PMID:12590135
Molecular Function	GO:0042802	identical protein binding	HDAC4	IPI	UniProtKB:P56524	Human	PMID:17360518
Molecular Function	GO:0060090	molecular adaptor activity	HDAC4	IDA		Human	PMID:31127039
Molecular Function	GO:0030955	potassium ion binding	HDAC4	IDA		Human	PMID:18614528
Molecular Function	GO:1990841	promoter-specific chromatin binding	Hdac4	IDA		Rat	PMID:21586557\|RGD:7241147
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P31946	Human	PMID:10869435
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P52292	Human	PMID:10869435
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P62258	Human	PMID:10869435
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P31946	Human	PMID:10958686
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q505F1	Human	PMID:11463856
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P61981	Human	PMID:11504882
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P62258	Human	PMID:11504882
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P63104	Human	PMID:11504882
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q9Y618	Human	PMID:11804585
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P63104	Human	PMID:15161933
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P08393	Human	PMID:15194749
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P31947	Human	PMID:15778465
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P63104	Human	PMID:15964851
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P41182	Human	PMID:16147992
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P63279	Human	PMID:16166628
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P31947	Human	PMID:16767219
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q9HCU9	Human	PMID:16919237
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P61981	Human	PMID:17159145
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q8AZK7	Human	PMID:17159145
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q04917	Human	PMID:17979178
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P27348	Human	PMID:18045992
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P61981	Human	PMID:18045992
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P62258	Human	PMID:18045992
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q04917	Human	PMID:18045992
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:O54946-2	Human	PMID:18163532
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P15336	Human	PMID:20116378
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P62258	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P10275	Human	PMID:21242980
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:A9UHW6	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q9H9E1,UniProtKB:Q9UQL6	Human	PMID:22649097
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P27348	Human	PMID:23752268
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P31946	Human	PMID:23752268
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P31947	Human	PMID:23752268
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P61981	Human	PMID:23752268
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P62258	Human	PMID:23752268
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P63104	Human	PMID:23752268
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q04917	Human	PMID:23752268
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q13761	Human	PMID:24229708
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P31946	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q09472	Human	PMID:24413532
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:O76015	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:O95751	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:O95967	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P61981	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q01850	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q15323	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q5JR59	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q6A162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q6NUQ1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q8ND90	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q96JN2-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q9H9E1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q04917	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P0DMV8	Human	PMID:27708256
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P0DMV9	Human	PMID:27708256
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P27348	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P61981	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P63104	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q04917	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:P31946	Human	PMID:33537682
Molecular Function	GO:0005515	protein binding	HDAC4	IPI	UniProtKB:Q9H9E1	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Hdac4	IPI	UniProtKB:Q64321	Mouse	MGI:MGI:5446998\|PMID:22730529
Molecular Function	GO:0005515	protein binding	Hdac4	IPI	UniProtKB:P23242	Mouse	MGI:MGI:4939823\|PMID:21282606
Molecular Function	GO:0005515	protein binding	Hdac4	IPI	UniProtKB:Q8VIM5	Mouse	MGI:MGI:3525929\|PMID:15601857
Molecular Function	GO:0005515	protein binding	Hdac4	IPI	UniProtKB:Q8VHK9	Mouse	MGI:MGI:5559667\|PMID:21590736
Molecular Function	GO:0005515	protein binding	Hdac4	IPI	PR:Q02591	Mouse	PMID:17568773
Molecular Function	GO:0005515	protein binding	Hdac4	IPI	PR:Q6P4S6	Mouse	PMID:22318228
Molecular Function	GO:0005515	protein binding	Hdac4	IPI	PR:O89114	Mouse	PMID:18555775
Molecular Function	GO:0005515	protein binding	Hdac4	IPI	PR:Q08775	Mouse	PMID:15537544
Molecular Function	GO:0005515	protein binding	Hdac4	IPI	PR:O54946	Mouse	PMID:16260608
Molecular Function	GO:0005515	protein binding	Hdac4	IPI	PR:Q9Z2V6	Mouse	PMID:18332106
Molecular Function	GO:0005515	protein binding	Hdac4	IPI	PR:Q9DAR1	Mouse	PMID:14576337
Molecular Function	GO:0005515	protein binding	Hdac4	IPI	PR:O54946	Mouse	PMID:18163532
Molecular Function	GO:0005515	protein binding	Hdac4	IPI	PR:Q8BUN5	Mouse	PMID:15990875
Molecular Function	GO:0005515	protein binding	Hdac4	IPI	RGD:621199	Rat	PMID:21464227\|RGD:7327144
Molecular Function	GO:0019901	protein kinase binding	Hdac4	IPI	UniProtKB:Q60670	Mouse	MGI:MGI:3712602\|PMID:17468767
Molecular Function	GO:0033558	protein lysine deacetylase activity	HDAC4	IDA		Human	PMID:18614528
Molecular Function	GO:0033558	protein lysine deacetylase activity	Hdac4	IDA		Mouse	PMID:18250163
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	HDAC4	IDA		Human	PMID:24413532
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	HDAC4	IPI	UniProtKB:P08047	Human	PMID:18850004
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	HDAC4	IPI	UniProtKB:Q61221	Human	PMID:19071119
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	HDAC4	IPI	UniProtKB:Q9NP62	Human	PMID:23867755
Molecular Function	GO:0043565	sequence-specific DNA binding	HDAC4	IDA		Human	PMID:19276356
Molecular Function	GO:0019789	SUMO transferase activity	HDAC4	EXP		Human	PMID:17218271
Molecular Function	GO:0000976	transcription cis-regulatory region binding	HDAC4	IDA		Human	PMID:18850004
Molecular Function	GO:0003714	transcription corepressor activity	Hdac4	IGI	MGI:MGI:1201674	Mouse	PMID:15990875
Molecular Function	GO:0008270	zinc ion binding	HDAC4	IDA		Human	PMID:18614528
Cellular Component	GO:0031672	A band	Hdac4	IDA		Rat	PMID:18250163\|RGD:2306453
Cellular Component	GO:0042641	actomyosin	Hdac4	IDA		Mouse	PMID:18250163
Cellular Component	GO:0000785	chromatin	HDAC4	IDA		Human	PMID:31127039
Cellular Component	GO:0005737	cytoplasm	HDAC4	IDA		Human	PMID:10869435
Cellular Component	GO:0005737	cytoplasm	HDAC4	IDA		Human	PMID:19281832
Cellular Component	GO:0005737	cytoplasm	Hdac4	IMP		Mouse	MGI:MGI:4365327\|PMID:19109424
Cellular Component	GO:0005737	cytoplasm	Hdac4	IDA		Mouse	PMID:22318228
Cellular Component	GO:0005737	cytoplasm	Hdac4	IDA		Rat	PMID:16767219\|RGD:2306455
Cellular Component	GO:0005829	cytosol	HDAC4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Hdac4	IDA		Mouse	PMID:17761942
Cellular Component	GO:0005829	cytosol	Hdac4	IDA		Rat	PMID:22360269\|RGD:7241148
Cellular Component	GO:0000118	histone deacetylase complex	HDAC4	IDA		Human	PMID:11804585
Cellular Component	GO:0031594	neuromuscular junction	Hdac4	IDA		Mouse	PMID:17873280
Cellular Component	GO:0016607	nuclear speck	HDAC4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HDAC4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	HDAC4	IDA		Human	PMID:10869435
Cellular Component	GO:0005634	nucleus	HDAC4	IDA		Human	PMID:19281832
Cellular Component	GO:0005634	nucleus	HDAC4	IDA		Human	PMID:23867755
Cellular Component	GO:0005634	nucleus	HDAC4	IDA		Human	PMID:26019235
Cellular Component	GO:0005634	nucleus	Hdac4	IMP		Mouse	MGI:MGI:4365327\|PMID:19109424
Cellular Component	GO:0005634	nucleus	Hdac4	IDA		Mouse	PMID:22318228
Cellular Component	GO:0005634	nucleus	Hdac4	IDA		Rat	PMID:16767219\|RGD:2306455
Cellular Component	GO:0005634	nucleus	Hdac4	IDA		Rat	PMID:22360269\|RGD:7241148
Cellular Component	GO:0032991	protein-containing complex	Hdac4	IDA		Rat	PMID:22360269\|RGD:7241148
Cellular Component	GO:0030017	sarcomere	Hdac4	IDA		Rat	PMID:18250163\|RGD:2306453
Cellular Component	GO:0017053	transcription repressor complex	HDAC4	IDA		Human	PMID:11804585
Cellular Component	GO:0030018	Z disc	Hdac4	IDA		Rat	PMID:18250163\|RGD:2306453
Biological Process	GO:0008283	cell population proliferation	Hdac4	IMP	MGI:MGI:3525071	Mouse	PMID:15537544
Biological Process	GO:0008283	cell population proliferation	Hdac4	IDA		Mouse	PMID:15537544
Biological Process	GO:0071260	cellular response to mechanical stimulus	Hdac4	IEP		Rat	PMID:19261284\|RGD:9590196
Biological Process	GO:0071374	cellular response to parathyroid hormone stimulus	Hdac4	IEP		Rat	PMID:20097749\|RGD:9681006
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Hdac4	IEP		Rat	PMID:22389387\|RGD:9681445
Biological Process	GO:0006338	chromatin remodeling	HDAC4	IDA		Human	PMID:18850004
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	hdac4	IMP	ZFIN:ZDB-MRPHLNO-120905-3,ZFIN:ZDB-MRPHLNO-120905-4	Zfish	PMID:22676467
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	hdac4	IMP	ZFIN:ZDB-MRPHLNO-120905-3	Zfish	PMID:22676467
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	hdac4	IMP	ZFIN:ZDB-MRPHLNO-120905-4	Zfish	PMID:22676467
Biological Process	GO:0040029	epigenetic regulation of gene expression	HDAC4	IMP		Human	PMID:24413532
Biological Process	GO:0016575	histone deacetylation	HDAC4	IDA		Human	PMID:10869435
Biological Process	GO:0016575	histone deacetylation	HDAC4	IMP		Human	PMID:18850004
Biological Process	GO:0070932	histone H3 deacetylation	HDAC4	IDA		Human	PMID:12590135
Biological Process	GO:0070933	histone H4 deacetylation	HDAC4	IDA		Human	PMID:12590135
Biological Process	GO:0008285	negative regulation of cell population proliferation	Hdac4	IMP	MGI:MGI:3525071	Mouse	PMID:15537544
Biological Process	GO:0008285	negative regulation of cell population proliferation	Hdac4	IDA		Mouse	PMID:15537544
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	HDAC4	IMP		Human	PMID:18850004
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	HDAC4	IDA		Human	PMID:10869435
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	HDAC4	IMP		Human	PMID:19276356
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Hdac4	IDA		Mouse	PMID:16260608
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Hdac4	IMP		Mouse	PMID:14576337
Biological Process	GO:0045820	negative regulation of glycolytic process	Hdac4	IMP		Mouse	MGI:MGI:4365327\|PMID:19109424
Biological Process	GO:1902894	negative regulation of miRNA transcription	Hdac4	IMP		Mouse	MGI:MGI:5754467\|PMID:24675724
Biological Process	GO:1902894	negative regulation of miRNA transcription	Hdac4	IGI	UniProtKB:P70288	Mouse	MGI:MGI:5754467\|PMID:24675724
Biological Process	GO:0010832	negative regulation of myotube differentiation	HDAC4	IMP		Human	PMID:10983972
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	Hdac4	IMP		Mouse	PMID:15990875
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	HDAC4	IGI	UniProtKB:P10085	Human	PMID:15743821
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	HDAC4	IGI	UniProtKB:P20695	Human	PMID:15743821
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	HDAC4	IGI	UniProtKB:Q8CFN5	Human	PMID:15743821
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	HDAC4	IDA		Human	PMID:16236793
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	HDAC4	IDA		Human	PMID:10869435
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	HDAC4	IMP		Human	PMID:18850004
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	HDAC4	IMP		Human	PMID:19276356
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hdac4	IGI	MGI:MGI:98725	Mouse	PMID:15990875
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hdac4	IDA		Mouse	PMID:17873280
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hdac4	IGI	MGI:MGI:99829	Mouse	PMID:15537544
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hdac4	IGI	MGI:MGI:2137495	Mouse	PMID:15601857
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hdac4	IGI	MGI:MGI:99458	Mouse	PMID:17336904
Biological Process	GO:0001755	neural crest cell migration	hdac4	IMP	ZFIN:ZDB-MRPHLNO-120905-4	Zfish	PMID:22676467
Biological Process	GO:0001755	neural crest cell migration	hdac4	IMP	ZFIN:ZDB-MRPHLNO-120905-3	Zfish	PMID:22676467
Biological Process	GO:0001755	neural crest cell migration	hdac4	IMP	ZFIN:ZDB-MRPHLNO-120905-3,ZFIN:ZDB-MRPHLNO-120905-4	Zfish	PMID:22676467
Biological Process	GO:0002076	osteoblast development	Hdac4	IMP		Mouse	PMID:15990875
Biological Process	GO:0001649	osteoblast differentiation	Hdac4	IMP		Mouse	PMID:15990875
Biological Process	GO:0034983	peptidyl-lysine deacetylation	HDAC4	IDA		Human	PMID:18614528
Biological Process	GO:0036073	perichondral ossification	hdac4	IMP	ZFIN:ZDB-GENO-191010-5	Zfish	PMID:30643696
Biological Process	GO:0036073	perichondral ossification	hdac4	IMP	ZFIN:ZDB-GENO-191011-3	Zfish	PMID:30643696
Biological Process	GO:0008284	positive regulation of cell population proliferation	HDAC4	IMP		Human	PMID:18850004
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	HDAC4	IMP		Human	PMID:19071119
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Hdac4	IMP		Mouse	MGI:MGI:4365327\|PMID:19109424
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	Hdac4	IMP		Rat	PMID:24166750\|RGD:9681442
Biological Process	GO:1902437	positive regulation of male mating behavior	Hdac4	IMP		Rat	PMID:21586557\|RGD:7241147
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Hdac4	IMP		Rat	PMID:23925573\|RGD:9681446
Biological Process	GO:0033235	positive regulation of protein sumoylation	HDAC4	IDA		Human	PMID:17696781
Biological Process	GO:1903428	positive regulation of reactive oxygen species biosynthetic process	Hdac4	IMP		Rat	PMID:24166750\|RGD:9681442
Biological Process	GO:0014911	positive regulation of smooth muscle cell migration	Hdac4	IMP		Rat	PMID:24166750\|RGD:9681442
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	Hdac4	IMP		Rat	PMID:24166750\|RGD:9681442
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HDAC4	IMP		Human	PMID:19071119
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hdac4	IMP		Mouse	MGI:MGI:4365327\|PMID:19109424
Biological Process	GO:0072114	pronephros morphogenesis	hdac4	IMP	ZFIN:ZDB-MRPHLNO-180926-6	Zfish	PMID:29633426
Biological Process	GO:0006476	protein deacetylation	HDAC4	IDA		Human	PMID:27708256
Biological Process	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	Hdac4	IMP		Mouse	PMID:18250163
Biological Process	GO:0090299	regulation of neural crest formation	hdac4	IMP	ZFIN:ZDB-MRPHLNO-120905-3	Zfish	PMID:22676467
Biological Process	GO:0090299	regulation of neural crest formation	hdac4	IMP	ZFIN:ZDB-MRPHLNO-120905-3,ZFIN:ZDB-MRPHLNO-120905-4	Zfish	PMID:22676467
Biological Process	GO:0090299	regulation of neural crest formation	hdac4	IMP	ZFIN:ZDB-MRPHLNO-120905-4	Zfish	PMID:22676467
Biological Process	GO:0043393	regulation of protein binding	HDAC4	IMP		Human	PMID:19071119
Biological Process	GO:0048742	regulation of skeletal muscle fiber development	Hdac4	IGI	MGI:MGI:1931221	Mouse	PMID:17786239
Biological Process	GO:0048742	regulation of skeletal muscle fiber development	Hdac4	IGI	MGI:MGI:1333784	Mouse	PMID:17786239
Biological Process	GO:1902809	regulation of skeletal muscle fiber differentiation	Hdac4	IGI	MGI:MGI:1333784	Mouse	PMID:17786239
Biological Process	GO:1902809	regulation of skeletal muscle fiber differentiation	Hdac4	IGI	MGI:MGI:1931221	Mouse	PMID:17786239
Biological Process	GO:0014894	response to denervation involved in regulation of muscle adaptation	Hdac4	IMP		Mouse	MGI:MGI:4365327\|PMID:19109424
Biological Process	GO:0070555	response to interleukin-1	HDAC4	IMP		Human	PMID:19281832
Biological Process	GO:0009410	response to xenobiotic stimulus	Hdac4	IDA		Rat	PMID:16767219\|RGD:2306455
Biological Process	GO:0001501	skeletal system development	Hdac4	IMP	MGI:MGI:3525071	Mouse	PMID:15537544
Biological Process	GO:0060337	type I interferon-mediated signaling pathway	HDAC4	IDA		Human	PMID:31127039

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.