Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HDC
  • Mouse genes Hdc
  • Rat genes Hdc
  • Zfish genes hdc
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hdc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016597	amino acid binding	Hdc	IDA		Rat	PMID:12204113|RGD:2303734
Molecular Function	GO:0016597	amino acid binding	Hdc	IDA		Rat	PMID:14622303|RGD:2303733
Molecular Function	GO:0016597	amino acid binding	Hdc	IDA		Rat	PMID:4449071|RGD:2303726
Molecular Function	GO:0016597	amino acid binding	Hdc	IDA		Rat	PMID:5898|RGD:2303727
Molecular Function	GO:0016597	amino acid binding	Hdc	IDA		Rat	PMID:7075603|RGD:2303728
Molecular Function	GO:0016597	amino acid binding	Hdc	IDA		Rat	PMID:9525922|RGD:2303735
Molecular Function	GO:0004398	histidine decarboxylase activity	HDC	IDA		Human	PMID:22767596
Molecular Function	GO:0004398	histidine decarboxylase activity	Hdc	IMP	MGI:MGI:2182618	Mouse	PMID:11478947
Molecular Function	GO:0004398	histidine decarboxylase activity	Hdc	IDA		Rat	PMID:12204113|RGD:2303734
Molecular Function	GO:0004398	histidine decarboxylase activity	Hdc	IDA		Rat	PMID:14622303|RGD:2303733
Molecular Function	GO:0004398	histidine decarboxylase activity	Hdc	IDA		Rat	PMID:4449071|RGD:2303726
Molecular Function	GO:0004398	histidine decarboxylase activity	Hdc	IDA		Rat	PMID:5898|RGD:2303727
Molecular Function	GO:0004398	histidine decarboxylase activity	Hdc	IDA		Rat	PMID:7075603|RGD:2303728
Molecular Function	GO:0004398	histidine decarboxylase activity	Hdc	IDA		Rat	PMID:9525922|RGD:2303735
Molecular Function	GO:0042802	identical protein binding	Hdc	IPI	RGD:2790	Rat	PMID:14622303|RGD:2303733
Molecular Function	GO:0005515	protein binding	HDC	IPI	UniProtKB:Q86UW9	Human	PMID:25416956
Molecular Function	GO:0030170	pyridoxal phosphate binding	Hdc	IDA		Rat	PMID:12204113|RGD:2303734
Molecular Function	GO:0030170	pyridoxal phosphate binding	Hdc	IDA		Rat	PMID:14622303|RGD:2303733
Molecular Function	GO:0030170	pyridoxal phosphate binding	Hdc	IDA		Rat	PMID:4449071|RGD:2303726
Molecular Function	GO:0030170	pyridoxal phosphate binding	Hdc	IDA		Rat	PMID:5898|RGD:2303727
Molecular Function	GO:0030170	pyridoxal phosphate binding	Hdc	IDA		Rat	PMID:7075603|RGD:2303728
Molecular Function	GO:0030170	pyridoxal phosphate binding	Hdc	IDA		Rat	PMID:9525922|RGD:2303735
Cellular Component	GO:0005829	cytosol	Hdc	IDA		Rat	PMID:9525922|RGD:2303735
Cellular Component	GO:0030425	dendrite	Hdc	IDA		Rat	PMID:2458167|RGD:2303729
Cellular Component	GO:0043025	neuronal cell body	Hdc	IDA		Rat	PMID:2458167|RGD:2303729
Cellular Component	GO:0045202	synapse	hdc	IMP	ZFIN:ZDB-MRPHLNO-120110-1	Zfish	PMID:21885652|ZFIN:ZDB-PUB-110907-18
Biological Process	GO:0007411	axon guidance	hdc	IMP	ZFIN:ZDB-MRPHLNO-120110-1	Zfish	PMID:21885652
Biological Process	GO:0007420	brain development	hdc	IMP	ZFIN:ZDB-MRPHLNO-120110-1	Zfish	PMID:21885652
Biological Process	GO:0007268	chemical synaptic transmission	hdc	IMP	ZFIN:ZDB-MRPHLNO-120110-1	Zfish	PMID:21885652
Biological Process	GO:0001694	histamine biosynthetic process	HDC	IDA		Human	PMID:22767596
Biological Process	GO:0001694	histamine biosynthetic process	Hdc	IMP	MGI:MGI:2182618	Mouse	PMID:11478947
Biological Process	GO:0001692	histamine metabolic process	Hdc	IDA		Rat	PMID:4449071|RGD:2303726
Biological Process	GO:0001692	histamine metabolic process	Hdc	IDA		Rat	PMID:5898|RGD:2303727
Biological Process	GO:0001692	histamine metabolic process	Hdc	IDA		Rat	PMID:7075603|RGD:2303728
Biological Process	GO:0001692	histamine metabolic process	Hdc	IDA		Rat	PMID:9525922|RGD:2303735
Biological Process	GO:0006548	histidine catabolic process	HDC	IDA		Human	PMID:22767596
Biological Process	GO:0006548	histidine catabolic process	Hdc	IMP		Mouse	PMID:11478947
Biological Process	GO:0006547	histidine metabolic process	Hdc	IDA		Rat	PMID:12204113|RGD:2303734
Biological Process	GO:0006547	histidine metabolic process	Hdc	IDA		Rat	PMID:14622303|RGD:2303733
Biological Process	GO:0006547	histidine metabolic process	Hdc	IDA		Rat	PMID:4449071|RGD:2303726
Biological Process	GO:0006547	histidine metabolic process	Hdc	IDA		Rat	PMID:5898|RGD:2303727
Biological Process	GO:0006547	histidine metabolic process	Hdc	IDA		Rat	PMID:7075603|RGD:2303728
Biological Process	GO:0006547	histidine metabolic process	Hdc	IDA		Rat	PMID:9525922|RGD:2303735
Biological Process	GO:0009416	response to light stimulus	hdc	IMP	ZFIN:ZDB-MRPHLNO-120110-1	Zfish	PMID:21885652

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern