Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HELQ
  • Mouse genes Helq
  • Rat genes Helq
  • Zfish genes helq
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Helq

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	HELQ	IPI	UniProtKB:O43502	Human	PMID:24005329
Molecular Function	GO:1990518	single-stranded 3'-5' DNA helicase activity	HELQ	IDA		Human	PMID:11751861
Molecular Function	GO:1990518	single-stranded 3'-5' DNA helicase activity	HELQ	IDA		Human	PMID:34316696
Molecular Function	GO:1990518	single-stranded 3'-5' DNA helicase activity	HELQ	IDA		Human	PMID:34937945
Cellular Component	GO:0005634	nucleus	HELQ	IDA		Human	PMID:34937945
Cellular Component	GO:0090734	site of DNA damage	HELQ	IDA		Human	PMID:34937945
Biological Process	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	HELQ	IDA		Human	PMID:34937945
Biological Process	GO:0097681	double-strand break repair via alternative nonhomologous end joining	HELQ	IDA		Human	PMID:34937945
Biological Process	GO:0000724	double-strand break repair via homologous recombination	HELQ	IMP		Human	PMID:19995904
Biological Process	GO:0045003	double-strand break repair via synthesis-dependent strand annealing	HELQ	IDA		Human	PMID:34937945
Biological Process	GO:1905168	positive regulation of double-strand break repair via homologous recombination	Helq	IDA		Mouse	MGI:MGI:5547892|PMID:24005329

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern