Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HELT
  • Mouse genes Helt
  • Rat genes Helt
  • Zfish genes helt
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Helt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Helt	IDA		Mouse	PMID:14764602
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Helt	IDA		Mouse	PMID:14764602
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Helt	IDA		Mouse	MGI:MGI:3040538|PMID:14764602
Molecular Function	GO:0042802	identical protein binding	Helt	IPI	PR:Q7TS99	Mouse	PMID:14764602
Molecular Function	GO:0005515	protein binding	Helt	IPI	PR:Q9QUS4	Mouse	PMID:14764602
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Helt	IDA		Mouse	MGI:MGI:3040538|PMID:14764602
Cellular Component	GO:0005634	nucleus	Helt	IDA		Mouse	PMID:16644143
Cellular Component	GO:0005667	transcription regulator complex	Helt	IDA		Mouse	PMID:14764602
Biological Process	GO:0007417	central nervous system development	Helt	IMP	MGI:MGI:3703237	Mouse	PMID:16968817
Biological Process	GO:0097154	GABAergic neuron differentiation	Helt	IGI	MGI:MGI:96919	Mouse	PMID:15071116
Biological Process	GO:0021858	GABAergic neuron differentiation in basal ganglia	Helt	IMP	MGI:MGI:3703237	Mouse	PMID:16968817
Biological Process	GO:0010467	gene expression	Helt	IMP	MGI:MGI:3703237	Mouse	PMID:16968817
Biological Process	GO:0035264	multicellular organism growth	Helt	IMP	MGI:MGI:3703237	Mouse	PMID:16968817
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Helt	IDA		Mouse	PMID:14764602
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Helt	IMP		Mouse	PMID:22920256
Biological Process	GO:0009791	post-embryonic development	Helt	IMP	MGI:MGI:3703237	Mouse	PMID:16968817
Biological Process	GO:0001967	suckling behavior	Helt	IMP	MGI:MGI:3703237	Mouse	PMID:16968817
Biological Process	GO:0006366	transcription by RNA polymerase II	Helt	IMP		Mouse	PMID:22920256

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern