Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HES1
  • Mouse genes Hes1
  • Rat genes Hes1
  • Zfish genes her6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hes1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Hes1	IDA		Rat	PMID:15607978|RGD:9685371
Molecular Function	GO:0003677	DNA binding	Hes1	IDA		Mouse	PMID:14764602
Molecular Function	GO:0003677	DNA binding	Hes1	IDA		Mouse	PMID:10851137
Molecular Function	GO:0003677	DNA binding	Hes1	IDA		Rat	PMID:9389649|RGD:9685378
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Hes1	IDA		Mouse	PMID:15870295
Molecular Function	GO:0001217	DNA-binding transcription repressor activity	Hes1	IDA		Mouse	MGI:MGI:4821067|PMID:17681138
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Hes1	IDA		Mouse	MGI:MGI:5285519|PMID:21259317
Molecular Function	GO:0070888	E-box binding	Hes1	IDA		Mouse	MGI:MGI:1859234|PMID:10851137
Molecular Function	GO:0070888	E-box binding	Hes1	IDA		Rat	PMID:19670267|RGD:9685170
Molecular Function	GO:0042826	histone deacetylase binding	HES1	IPI	UniProtKB:Q96EB6	Human	PMID:12535671
Molecular Function	GO:0043398	HLH domain binding	Hes1	IDA		Mouse	MGI:MGI:4821067|PMID:17681138
Molecular Function	GO:0042802	identical protein binding	Hes1	IPI	RGD:62081	Rat	PMID:9389649|RGD:9685378
Molecular Function	GO:0008432	JUN kinase binding	Hes1	IPI	RGD:621506	Rat	PMID:22302822|RGD:9685391
Molecular Function	GO:0071820	N-box binding	Hes1	IDA		Mouse	MGI:MGI:1859234|PMID:10851137
Molecular Function	GO:0071820	N-box binding	Hes1	IDA		Mouse	MGI:MGI:4821067|PMID:17681138
Molecular Function	GO:0071820	N-box binding	Hes1	IDA		Rat	PMID:22302822|RGD:9685391
Molecular Function	GO:0005515	protein binding	HES1	IPI	UniProtKB:Q96EB6	Human	PMID:12535671
Molecular Function	GO:0005515	protein binding	Hes1	IPI	UniProtKB:P42227|UniProtKB:Q62120	Mouse	MGI:MGI:5284803|PMID:15156153
Molecular Function	GO:0005515	protein binding	Hes1	IPI	UniProtKB:P41136	Mouse	MGI:MGI:4821067|PMID:17681138
Molecular Function	GO:0005515	protein binding	Hes1	IPI	UniProtKB:P35428|UniProtKB:Q62440|UniProtKB:Q9DBX7	Mouse	MGI:MGI:5285519|PMID:21259317
Molecular Function	GO:0005515	protein binding	Hes1	IPI	UniProtKB:P20067|UniProtKB:P41133	Mouse	MGI:MGI:4821067|PMID:17681138
Molecular Function	GO:0005515	protein binding	Hes1	IPI	UniProtKB:Q9QUS4	Rat	PMID:11486045|RGD:8553415
Molecular Function	GO:0005515	protein binding	Hes1	IPI	RGD:1319465	Rat	PMID:8687460|RGD:8553567
Molecular Function	GO:0042803	protein homodimerization activity	Hes1	IDA		Mouse	MGI:MGI:5285519|PMID:21259317
Molecular Function	GO:0044877	protein-containing complex binding	Hes1	IDA		Rat	PMID:11238932|RGD:9685363
Molecular Function	GO:0051087	protein-folding chaperone binding	Hes1	IDA		Mouse	PMID:16314515
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Hes1	IPI	UniProtKB:Q9JHE6	Mouse	MGI:MGI:1859234|PMID:10851137
Molecular Function	GO:0043565	sequence-specific DNA binding	Hes1	IDA		Rat	PMID:11486045|RGD:8553415
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HES1	IDA		Human	PMID:28473536
Molecular Function	GO:0001222	transcription corepressor binding	Hes1	IPI	UniProtKB:Q04724	Rat	PMID:8687460|RGD:8553567
Cellular Component	GO:0000785	chromatin	Hes1	IDA		Rat	PMID:15607978|RGD:9685371
Cellular Component	GO:0005737	cytoplasm	Hes1	IDA		Mouse	PMID:15645444
Cellular Component	GO:0005622	intracellular anatomical structure	Hes1	IDA		Mouse	PMID:16489008
Cellular Component	GO:0016363	nuclear matrix	Hes1	IDA		Rat	PMID:11035023|RGD:9685356
Cellular Component	GO:0005654	nucleoplasm	HES1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Hes1	IDA		Mouse	MGI:MGI:5284803|PMID:15156153
Cellular Component	GO:0005634	nucleus	Hes1	IDA		Mouse	MGI:MGI:2655020|PMID:12666205
Cellular Component	GO:0005634	nucleus	Hes1	IDA		Mouse	PMID:17079689
Cellular Component	GO:0005634	nucleus	Hes1	IDA		Mouse	PMID:15645444
Cellular Component	GO:0005634	nucleus	Hes1	IDA		Mouse	PMID:10952889
Cellular Component	GO:0005634	nucleus	Hes1	IDA		Mouse	PMID:23284756
Cellular Component	GO:0032991	protein-containing complex	Hes1	IDA		Mouse	MGI:MGI:4821067|PMID:17681138
Biological Process	GO:0021984	adenohypophysis development	Hes1	IMP	MGI:MGI:3808031	Mouse	PMID:18996108
Biological Process	GO:0035881	amacrine cell differentiation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:16038893
Biological Process	GO:0009952	anterior/posterior pattern specification	her6	IMP		Zfish	PMID:15023930
Biological Process	GO:0035909	aorta morphogenesis	Hes1	IMP		Mouse	MGI:MGI:4453944|PMID:20122914
Biological Process	GO:0048844	artery morphogenesis	Hes1	IMP		Mouse	MGI:MGI:4453944|PMID:20122914
Biological Process	GO:0035910	ascending aorta morphogenesis	Hes1	IMP		Mouse	MGI:MGI:4354447|PMID:19609448
Biological Process	GO:0030509	BMP signaling pathway	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:18579678
Biological Process	GO:0021870	Cajal-Retzius cell differentiation	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:18579678
Biological Process	GO:0061309	cardiac neural crest cell development involved in outflow tract morphogenesis	Hes1	IMP		Mouse	PMID:19609448
Biological Process	GO:0007155	cell adhesion	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:15496443
Biological Process	GO:0045165	cell fate commitment	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:10952889
Biological Process	GO:0001709	cell fate determination	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:11425898
Biological Process	GO:0048469	cell maturation	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:15496443
Biological Process	GO:0016477	cell migration	Hes1	IGI	MGI:MGI:109330	Mouse	PMID:18996108
Biological Process	GO:0048667	cell morphogenesis involved in neuron differentiation	Hes1	IGI	MGI:MGI:104877	Mouse	PMID:11500373
Biological Process	GO:0008283	cell population proliferation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:16038893
Biological Process	GO:0008283	cell population proliferation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:17426285
Biological Process	GO:0071398	cellular response to fatty acid	Hes1	IEP		Rat	PMID:19272428|RGD:9685381
Biological Process	GO:0071347	cellular response to interleukin-1	Hes1	IEP		Rat	PMID:23589286|RGD:9685382
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Hes1	IMP		Rat	PMID:9389649|RGD:9685378
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Hes1	IEP		Rat	PMID:23589286|RGD:9685382
Biological Process	GO:0090102	cochlea development	Hes1	IGI	MGI:MGI:1341884	Mouse	PMID:18302773
Biological Process	GO:0090102	cochlea development	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:18302773
Biological Process	GO:0072049	comma-shaped body morphogenesis	Hes1	IEP		Mouse	MGI:MGI:3576186|PMID:15821257
Biological Process	GO:0061009	common bile duct development	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:19619492
Biological Process	GO:0003143	embryonic heart tube morphogenesis	Hes1	IMP		Mouse	MGI:MGI:4354447|PMID:19609448
Biological Process	GO:0035883	enteroendocrine cell differentiation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:18173746
Biological Process	GO:0090162	establishment of epithelial cell polarity	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:21300049
Biological Process	GO:0090162	establishment of epithelial cell polarity	Hes1	IGI	MGI:MGI:1341800	Mouse	PMID:21300049
Biological Process	GO:0021861	forebrain radial glial cell differentiation	Hes1	IDA		Rat	PMID:11399758|RGD:8554692
Biological Process	GO:0072012	glomerulus vasculature development	Hes1	IEP		Mouse	MGI:MGI:3576186|PMID:15821257
Biological Process	GO:0035315	hair cell differentiation	Hes1	IMP		Rat	PMID:11023859|RGD:9685386
Biological Process	GO:0021575	hindbrain morphogenesis	Hes1	IGI	MGI:MGI:104877	Mouse	PMID:11500373
Biological Process	GO:0001701	in utero embryonic development	Hes1	IGI	MGI:MGI:104877	Mouse	PMID:11500373
Biological Process	GO:0002085	inhibition of neuroepithelial cell differentiation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:10952889
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	Hes1	IGI	MGI:MGI:1341800	Mouse	PMID:21300049
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:21300049
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	Hes1	IGI	MGI:MGI:1341800	Mouse	PMID:21300049
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:21300049
Biological Process	GO:0060716	labyrinthine layer blood vessel development	Hes1	IMP		Mouse	MGI:MGI:4453944|PMID:20122914
Biological Process	GO:0046331	lateral inhibition	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:10804175
Biological Process	GO:0001889	liver development	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:15578515
Biological Process	GO:0030324	lung development	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:10952889
Biological Process	GO:0072282	metanephric nephron tubule morphogenesis	Hes1	IEP		Mouse	MGI:MGI:3056024|PMID:15465493
Biological Process	GO:0030901	midbrain development	Hes1	IGI	MGI:MGI:104877	Mouse	PMID:11500373
Biological Process	GO:0021555	midbrain-hindbrain boundary morphogenesis	Hes1	IGI	MGI:MGI:104877	Mouse	PMID:11500373
Biological Process	GO:1902870	negative regulation of amacrine cell differentiation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:16038893
Biological Process	GO:0090281	negative regulation of calcium ion import	Hes1	IMP		Rat	PMID:22302822|RGD:9685391
Biological Process	GO:0045596	negative regulation of cell differentiation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:17426285
Biological Process	GO:1905934	negative regulation of cell fate determination	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:11425898
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	Hes1	IDA		Mouse	MGI:MGI:1859234|PMID:10851137
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	HES1	IDA		Human	PMID:12535671
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Hes1	IMP		Mouse	MGI:MGI:3625195|PMID:12208538
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Hes1	IDA		Rat	PMID:22302822|RGD:9685391
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Hes1	IDA		Rat	PMID:8649374|RGD:8553741
Biological Process	GO:2000978	negative regulation of forebrain neuron differentiation	Hes1	IDA		Rat	PMID:11399758|RGD:8554692
Biological Process	GO:0010629	negative regulation of gene expression	Hes1	IMP		Rat	PMID:19670267|RGD:9685170
Biological Process	GO:0060253	negative regulation of glial cell proliferation	Hes1	IDA		Mouse	MGI:MGI:2655020|PMID:12666205
Biological Process	GO:0045608	negative regulation of inner ear auditory receptor cell differentiation	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:21300049
Biological Process	GO:0045608	negative regulation of inner ear auditory receptor cell differentiation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:11425898
Biological Process	GO:0045608	negative regulation of inner ear auditory receptor cell differentiation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:11023859
Biological Process	GO:0045608	negative regulation of inner ear auditory receptor cell differentiation	Hes1	IGI	MGI:MGI:1341800	Mouse	PMID:21300049
Biological Process	GO:2000981	negative regulation of inner ear receptor cell differentiation	Hes1	IMP		Mouse	MGI:MGI:3625195|PMID:12208538
Biological Process	GO:0050768	negative regulation of neurogenesis	Hes1	IMP		Rat	PMID:11399758|RGD:8554692
Biological Process	GO:0045665	negative regulation of neuron differentiation	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:18579678
Biological Process	GO:0045665	negative regulation of neuron differentiation	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:15496443
Biological Process	GO:0045665	negative regulation of neuron differentiation	Hes1	IGI	MGI:MGI:97363	Mouse	PMID:10205173
Biological Process	GO:0045665	negative regulation of neuron differentiation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:16038893
Biological Process	GO:0045665	negative regulation of neuron differentiation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:10205173
Biological Process	GO:0045665	negative regulation of neuron differentiation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:10952889
Biological Process	GO:0045665	negative regulation of neuron differentiation	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:10205173
Biological Process	GO:0010977	negative regulation of neuron projection development	Hes1	IMP		Rat	PMID:9389649|RGD:9685378
Biological Process	GO:0048715	negative regulation of oligodendrocyte differentiation	Hes1	IDA		Mouse	MGI:MGI:2655020|PMID:12666205
Biological Process	GO:0048715	negative regulation of oligodendrocyte differentiation	Hes1	IMP		Rat	PMID:12666205|RGD:9685388
Biological Process	GO:2000227	negative regulation of pancreatic A cell differentiation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:10615124
Biological Process	GO:2000974	negative regulation of pro-B cell differentiation	HES1	IMP		Human	PMID:12032823
Biological Process	GO:2000737	negative regulation of stem cell differentiation	HES1	IMP		Human	PMID:19682396
Biological Process	GO:0061106	negative regulation of stomach neuroendocrine cell differentiation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:18173746
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	HES1	IDA		Human	PMID:12032823
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	HES1	IDA		Human	PMID:12535671
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hes1	IMP		Mouse	MGI:MGI:4354447|PMID:19609448
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hes1	IDA		Mouse	MGI:MGI:1859234|PMID:10851137
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hes1	IMP		Mouse	MGI:MGI:4453944|PMID:20122914
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hes1	IDA		Mouse	MGI:MGI:5285519|PMID:21259317
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hes1	IDA		Mouse	PMID:15870295
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:15870295
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:19050759
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hes1	IGI	MGI:MGI:104877	Mouse	PMID:19050759
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hes1	IDA		Mouse	PMID:16314515
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hes1	IDA		Mouse	PMID:11260262
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hes1	IMP		Rat	PMID:11486045|RGD:8553415
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hes1	IMP		Rat	PMID:19670267|RGD:9685170
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hes1	IDA		Rat	PMID:8649374|RGD:8553741
Biological Process	GO:0021915	neural tube development	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:10804175
Biological Process	GO:0021915	neural tube development	Hes1	IGI	MGI:MGI:104877	Mouse	PMID:11500373
Biological Process	GO:0061101	neuroendocrine cell differentiation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:10952889
Biological Process	GO:0030182	neuron differentiation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:16038893
Biological Process	GO:0030182	neuron differentiation	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:15496443
Biological Process	GO:0030182	neuron differentiation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:10205173
Biological Process	GO:0030182	neuron differentiation	Hes1	IGI	MGI:MGI:97363	Mouse	PMID:10205173
Biological Process	GO:0030182	neuron differentiation	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:10205173
Biological Process	GO:0030182	neuron differentiation	Hes1	IEP		Rat	PMID:9634594|RGD:9685379
Biological Process	GO:0097150	neuronal stem cell population maintenance	HES1	IEP		Human	PMID:19682396
Biological Process	GO:0097150	neuronal stem cell population maintenance	Hes1	IMP		Mouse	MGI:MGI:5142379|PMID:11399758
Biological Process	GO:0097150	neuronal stem cell population maintenance	Hes1	IDA		Rat	PMID:11399758|RGD:8554692
Biological Process	GO:0007219	Notch signaling pathway	HES1	IDA		Human	PMID:16160079
Biological Process	GO:0007219	Notch signaling pathway	HES1	IMP		Human	PMID:19682396
Biological Process	GO:0007219	Notch signaling pathway	Hes1	IDA		Mouse	PMID:25535395
Biological Process	GO:0007219	Notch signaling pathway	her6	IMP		Zfish	PMID:15023930
Biological Process	GO:0021557	oculomotor nerve development	Hes1	IGI	MGI:MGI:104877	Mouse	PMID:11500373
Biological Process	GO:0003151	outflow tract morphogenesis	Hes1	IMP		Mouse	MGI:MGI:4453944|PMID:20122914
Biological Process	GO:0003151	outflow tract morphogenesis	Hes1	IMP		Mouse	PMID:19609448
Biological Process	GO:0031016	pancreas development	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:19619492
Biological Process	GO:0003310	pancreatic A cell differentiation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:10615124
Biological Process	GO:0007389	pattern specification process	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:18302773
Biological Process	GO:0007389	pattern specification process	Hes1	IGI	MGI:MGI:1341884	Mouse	PMID:18302773
Biological Process	GO:0061626	pharyngeal arch artery morphogenesis	Hes1	IMP		Mouse	MGI:MGI:4453944|PMID:20122914
Biological Process	GO:0021983	pituitary gland development	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:17015435
Biological Process	GO:0021983	pituitary gland development	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:17426285
Biological Process	GO:0021983	pituitary gland development	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:17426285
Biological Process	GO:0048711	positive regulation of astrocyte differentiation	Hes1	IDA		Mouse	MGI:MGI:2655020|PMID:12666205
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:18579678
Biological Process	GO:0008284	positive regulation of cell population proliferation	Hes1	IMP		Mouse	MGI:MGI:4453944|PMID:20122914
Biological Process	GO:0008284	positive regulation of cell population proliferation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:17426285
Biological Process	GO:0008284	positive regulation of cell population proliferation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:16038893
Biological Process	GO:0043388	positive regulation of DNA binding	Hes1	IDA		Mouse	MGI:MGI:5284803|PMID:15156153
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Hes1	IMP		Mouse	MGI:MGI:3625195|PMID:12208538
Biological Process	GO:0010628	positive regulation of gene expression	Hes1	IMP		Rat	PMID:15607978|RGD:9685371
Biological Process	GO:0045687	positive regulation of glial cell differentiation	Hes1	IMP		Rat	PMID:10839357|RGD:704354
Biological Process	GO:0045977	positive regulation of mitotic cell cycle, embryonic	Hes1	IMP		Mouse	MGI:MGI:4354447|PMID:19609448
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	Hes1	IMP		Mouse	MGI:MGI:3625195|PMID:12208538
Biological Process	GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT	Hes1	IDA		Mouse	MGI:MGI:5284803|PMID:15156153
Biological Process	GO:0042102	positive regulation of T cell proliferation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:15870295
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hes1	IMP		Mouse	MGI:MGI:4453944|PMID:20122914
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hes1	IMP		Mouse	MGI:MGI:4354447|PMID:19609448
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:19050759
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hes1	IGI	MGI:MGI:104877	Mouse	PMID:19050759
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hes1	IGI	MGI:MGI:104877	Mouse	PMID:11500373
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	Hes1	IDA		Mouse	MGI:MGI:5284803|PMID:15156153
Biological Process	GO:0065003	protein-containing complex assembly	Hes1	IDA		Mouse	MGI:MGI:5284803|PMID:15156153
Biological Process	GO:0050678	regulation of epithelial cell proliferation	Hes1	IGI	MGI:MGI:1341800	Mouse	PMID:21300049
Biological Process	GO:0050678	regulation of epithelial cell proliferation	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:21300049
Biological Process	GO:0045598	regulation of fat cell differentiation	Hes1	IMP		Mouse	PMID:15060169
Biological Process	GO:0050767	regulation of neurogenesis	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:10804175
Biological Process	GO:0050767	regulation of neurogenesis	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:19050759
Biological Process	GO:0050767	regulation of neurogenesis	Hes1	IGI	MGI:MGI:104877	Mouse	PMID:19050759
Biological Process	GO:0050767	regulation of neurogenesis	her6	IMP	ZFIN:ZDB-MRPHLNO-120605-2	Zfish	PMID:22595676
Biological Process	GO:0045664	regulation of neuron differentiation	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:10804175
Biological Process	GO:0045664	regulation of neuron differentiation	her6	IMP	ZFIN:ZDB-MRPHLNO-100104-1	Zfish	PMID:19903880
Biological Process	GO:0043254	regulation of protein-containing complex assembly	Hes1	IDA		Rat	PMID:22302822|RGD:9685391
Biological Process	GO:0046425	regulation of receptor signaling pathway via JAK-STAT	Hes1	IDA		Mouse	MGI:MGI:5284803|PMID:15156153
Biological Process	GO:0003266	regulation of secondary heart field cardioblast proliferation	Hes1	IMP		Mouse	PMID:19609448
Biological Process	GO:0048505	regulation of timing of cell differentiation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:8543157
Biological Process	GO:0048505	regulation of timing of cell differentiation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:17015435
Biological Process	GO:0060164	regulation of timing of neuron differentiation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:8543157
Biological Process	GO:0060164	regulation of timing of neuron differentiation	Hes1	IGI	MGI:MGI:104877	Mouse	PMID:11500373
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Hes1	IGI	MGI:MGI:1341884	Mouse	PMID:20628571
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Hes1	IGI	MGI:MGI:99414	Mouse	PMID:20628571
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Hes1	IGI	MGI:MGI:99829	Mouse	PMID:20628571
Biological Process	GO:0072141	renal interstitial fibroblast development	Hes1	IEP		Mouse	MGI:MGI:3576186|PMID:15821257
Biological Process	GO:0043279	response to alkaloid	Hes1	IEP		Rat	PMID:23545940|RGD:9685361
Biological Process	GO:0014070	response to organic cyclic compound	Hes1	IEP		Rat	PMID:15862623|RGD:9685384
Biological Process	GO:0097066	response to thyroid hormone	Hes1	IEP		Rat	PMID:15862623|RGD:9685384
Biological Process	GO:0072050	S-shaped body morphogenesis	Hes1	IEP		Mouse	MGI:MGI:3576186|PMID:15821257
Biological Process	GO:0007224	smoothened signaling pathway	Hes1	IDA		Mouse	PMID:19124651
Biological Process	GO:0035019	somatic stem cell population maintenance	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:10615124
Biological Process	GO:0001757	somite specification	her6	IMP		Zfish	PMID:15023930
Biological Process	GO:0061102	stomach neuroendocrine cell differentiation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:18173746
Biological Process	GO:0042098	T cell proliferation	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:15870295
Biological Process	GO:0021537	telencephalon development	Hes1	IGI	MGI:MGI:104876	Mouse	PMID:18579678
Biological Process	GO:0021537	telencephalon development	Hes1	IMP	MGI:MGI:2149672	Mouse	PMID:19050759
Biological Process	GO:0021794	thalamus development	her6	IMP	ZFIN:ZDB-MRPHLNO-100104-1	Zfish	PMID:19903880
Biological Process	GO:0048538	thymus development	Hes1	IMP		Mouse	MGI:MGI:4453944|PMID:20122914
Biological Process	GO:0021558	trochlear nerve development	Hes1	IGI	MGI:MGI:104877	Mouse	PMID:11500373
Biological Process	GO:0060675	ureteric bud morphogenesis	Hes1	IEP		Mouse	MGI:MGI:3576186|PMID:15821257
Biological Process	GO:0097084	vascular associated smooth muscle cell development	Hes1	IMP		Mouse	MGI:MGI:4453944|PMID:20122914
Biological Process	GO:0003281	ventricular septum development	Hes1	IMP		Mouse	MGI:MGI:4453944|PMID:20122914
Biological Process	GO:0060412	ventricular septum morphogenesis	Hes1	IMP		Mouse	MGI:MGI:4354447|PMID:19609448

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern