Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HEXA
  • Mouse genes Hexa
  • Rat genes Hexa
  • Zfish genes hexa
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hexa

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008375	acetylglucosaminyltransferase activity	HEXA	IDA		Human	PMID:25645918
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	HEXA	IDA		Human	PMID:8123671
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	HEXA	IDA		Human	PMID:8672428
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	HEXA	IDA		Human	PMID:9694901
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexa	IGI	MGI:MGI:96074	Mouse	PMID:22451654
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexa	IGI	MGI:MGI:96074	Mouse	PMID:11707436
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexa	IMP	MGI:MGI:3581540	Mouse	PMID:10196372
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexa	IMP	MGI:MGI:3581540	Mouse	PMID:8747922
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexa	IDA		Mouse	PMID:1914521
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexa	IDA		Mouse	PMID:8747922
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexa	IMP	MGI:MGI:2429698	Mouse	PMID:8789434
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexa	IDA		Mouse	PMID:9417048
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexa	IGI	MGI:MGI:96074	Mouse	PMID:8896570
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexa	IDA		Mouse	PMID:28728022
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexa	IMP	MGI:MGI:1857181	Mouse	PMID:7937929
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Hexa	IDA		Mouse	PMID:11854359
Molecular Function	GO:0005515	protein binding	HEXA	IPI	UniProtKB:P07686	Human	PMID:16698036
Molecular Function	GO:0005515	protein binding	HEXA	IPI	UniProtKB:P07686	Human	PMID:28514442
Molecular Function	GO:0046982	protein heterodimerization activity	HEXA	IDA		Human	PMID:6230359
Cellular Component	GO:0042582	azurophil granule	HEXA	IDA		Human	PMID:25645918
Cellular Component	GO:1905379	beta-N-acetylhexosaminidase complex	HEXA	IDA		Human	PMID:11707436
Cellular Component	GO:1905379	beta-N-acetylhexosaminidase complex	HEXA	IPI		Human	PMID:16698036
Cellular Component	GO:0005829	cytosol	HEXA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	HEXA	HDA		Human	PMID:23533145
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	HEXA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005764	lysosome	Hexa	IMP	MGI:MGI:2429698	Mouse	PMID:22451654
Cellular Component	GO:0005764	lysosome	Hexa	IDA		Mouse	PMID:9645704
Cellular Component	GO:0005764	lysosome	Hexa	IDA		Mouse	PMID:11854359
Cellular Component	GO:0016020	membrane	HEXA	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Hexa	IDA		Mouse	PMID:11854359
Biological Process	GO:0007628	adult walking behavior	Hexa	IMP	MGI:MGI:2429698	Mouse	PMID:14972652
Biological Process	GO:0048667	cell morphogenesis involved in neuron differentiation	Hexa	IMP	MGI:MGI:2429698	Mouse	PMID:14972652
Biological Process	GO:0030209	dermatan sulfate catabolic process	Hexa	IGI	MGI:MGI:96074	Mouse	PMID:11707436
Biological Process	GO:0006689	ganglioside catabolic process	HEXA	IDA		Human	PMID:8123671
Biological Process	GO:0006689	ganglioside catabolic process	HEXA	IDA		Human	PMID:8672428
Biological Process	GO:0006689	ganglioside catabolic process	HEXA	IDA		Human	PMID:9694901
Biological Process	GO:0006689	ganglioside catabolic process	Hexa	IMP	MGI:MGI:2429698	Mouse	PMID:9645704
Biological Process	GO:0006689	ganglioside catabolic process	Hexa	IMP	MGI:MGI:1857181	Mouse	PMID:9223328
Biological Process	GO:0006689	ganglioside catabolic process	Hexa	IMP	MGI:MGI:1857181	Mouse	PMID:7937929
Biological Process	GO:0006689	ganglioside catabolic process	Hexa	IMP	MGI:MGI:2429698	Mouse	PMID:8789434
Biological Process	GO:0006024	glycosaminoglycan biosynthetic process	HEXA	IDA		Human	PMID:25645918
Biological Process	GO:0030203	glycosaminoglycan metabolic process	HEXA	IDA		Human	PMID:11707436
Biological Process	GO:0030203	glycosaminoglycan metabolic process	HEXA	IDA		Human	PMID:25645918
Biological Process	GO:0030203	glycosaminoglycan metabolic process	Hexa	IMP		Mouse	MGI:MGI:3722584|PMID:11707436
Biological Process	GO:0030203	glycosaminoglycan metabolic process	Hexa	IGI	MGI:MGI:96074	Mouse	PMID:8896570
Biological Process	GO:0030214	hyaluronan catabolic process	Hexa	IMP	MGI:MGI:2429698	Mouse	PMID:22451654
Biological Process	GO:0019915	lipid storage	Hexa	IMP	MGI:MGI:2429698	Mouse	PMID:14972652
Biological Process	GO:0019915	lipid storage	Hexa	IMP	MGI:MGI:1857181	Mouse	PMID:9223328
Biological Process	GO:0019915	lipid storage	Hexa	IMP	MGI:MGI:1857181	Mouse	PMID:10021458
Biological Process	GO:0007626	locomotory behavior	Hexa	IGI	MGI:MGI:96074	Mouse	PMID:8896570
Biological Process	GO:0007040	lysosome organization	Hexa	IGI	MGI:MGI:96074	Mouse	PMID:8896570
Biological Process	GO:0007040	lysosome organization	Hexa	IGI	MGI:MGI:96074	Mouse	PMID:9184660
Biological Process	GO:0007040	lysosome organization	Hexa	IMP	MGI:MGI:2429698	Mouse	PMID:14972652
Biological Process	GO:0007040	lysosome organization	Hexa	IMP	MGI:MGI:2429698	Mouse	PMID:10591619
Biological Process	GO:0007040	lysosome organization	Hexa	IMP	MGI:MGI:2429698	Mouse	PMID:9645704
Biological Process	GO:0007040	lysosome organization	Hexa	IMP	MGI:MGI:1857181	Mouse	PMID:7937929
Biological Process	GO:0007040	lysosome organization	Hexa	IMP	MGI:MGI:2429698	Mouse	PMID:9302266
Biological Process	GO:0007040	lysosome organization	Hexa	IMP	MGI:MGI:3581540	Mouse	PMID:8747922
Biological Process	GO:0007040	lysosome organization	Hexa	IMP	MGI:MGI:1857181	Mouse	PMID:9103204
Biological Process	GO:0051651	maintenance of location in cell	Hexa	IMP	MGI:MGI:2429698	Mouse	PMID:14972652
Biological Process	GO:0051651	maintenance of location in cell	Hexa	IMP	MGI:MGI:1857181	Mouse	PMID:9223328
Biological Process	GO:0042552	myelination	Hexa	IGI	MGI:MGI:96074	Mouse	PMID:9184660
Biological Process	GO:0050885	neuromuscular process controlling balance	Hexa	IGI	MGI:MGI:96074	Mouse	PMID:8896570
Biological Process	GO:0050884	neuromuscular process controlling posture	Hexa	IMP	MGI:MGI:2429698	Mouse	PMID:14972652
Biological Process	GO:0007605	sensory perception of sound	Hexa	IGI	MGI:MGI:96074	Mouse	PMID:8896570
Biological Process	GO:0019953	sexual reproduction	Hexa	IMP	MGI:MGI:2429698	Mouse	PMID:9645704
Biological Process	GO:0001501	skeletal system development	Hexa	IGI	MGI:MGI:96074	Mouse	PMID:8896570
Biological Process	GO:0001501	skeletal system development	Hexa	IGI	MGI:MGI:96074	Mouse	PMID:9184660
Biological Process	GO:0060395	SMAD protein signal transduction	Hexa	IDA		Mouse	PMID:23390484

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern